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Ryan P Murelli

from Belleville, NJ
Age ~43

Ryan Murelli Phones & Addresses

  • 169 Beech St, Belleville, NJ 07109
  • North Bergen, NJ
  • 361 Chestnut Hill Rd, Torrington, CT 06790
  • 1909 Beacon St, Brookline, MA 02445

Work

Company: Brooklyn college Aug 2019 Position: Professor

Education

Degree: Doctorates, Doctor of Philosophy School / High School: Boston College 2002 to 2007 Specialities: Philosophy, Organic Chemistry

Skills

University Teaching • Synthetic Organic Chemistry • Medicinal Chemistry • Organic Chemistry • Chemical Biology • Organic Synthesis

Industries

Higher Education

Resumes

Resumes

Ryan Murelli Photo 1

Professor

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Location:
365 5Th Ave, New York, NY 10001
Industry:
Higher Education
Work:
Brooklyn College
Professor

Brooklyn College 2017 - Aug 2019
Associate Professor

Brooklyn College Sep 2010 - Aug 2017
Assistant Professor

Yale University Sep 2007 - Aug 2010
Postdoctoral Research Associate

The Graduate Center, City University of New York (Cuny) Sep 2007 - Aug 2010
Joint Appointment , Chair of Organic Subdiscipline
Education:
Boston College 2002 - 2007
Doctorates, Doctor of Philosophy, Philosophy, Organic Chemistry
Hamilton College 1998 - 2002
Bachelors, Bachelor of Arts, Chemistry
Skills:
University Teaching
Synthetic Organic Chemistry
Medicinal Chemistry
Organic Chemistry
Chemical Biology
Organic Synthesis

Publications

Us Patents

Chimeric Small Molecules For The Recruitment Of Antibodies To Cancer Cells

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US Patent:
20120034295, Feb 9, 2012
Filed:
Jun 30, 2011
Appl. No.:
13/173480
Inventors:
David Spiegel - New Haven CT, US
Ryan Murelli - Torrington CT, US
Andrew Zhang - New Haven CT, US
International Classification:
A61K 9/127
US Classification:
424450
Abstract:
The present invention relates to chimeric chemical compounds which are used to recruit antibodies to cancer cells, in particular, prostate cancer cells or metastasized prostate cancer cells. The compounds according to the present invention comprise an antibody binding terminus (ABT) moiety covalently bonded to a cell binding terminus (CBT) through a linker and optionally, a connector molecule.

Chimeric Small Molecules For The Recruitment Of Antibodies To Cancer Cells

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US Patent:
20110201563, Aug 18, 2011
Filed:
May 13, 2009
Appl. No.:
12/991926
Inventors:
David Spiegel - New Haven CT, US
Ryan Murelli - Torrington CT, US
Andrew Zhang - New Haven CT, US
Assignee:
YALE UNIVERSITY - New Haven CT
International Classification:
A61K 31/702
A61K 31/675
A61K 31/66
A61K 31/4192
A61K 31/195
C07H 99/00
C07F 9/28
C07D 249/04
C07C 321/00
C07D 403/14
A61P 35/02
A61P 35/00
US Classification:
514 25, 514 93, 514114, 514359, 514562, 536 179, 548119, 548255, 562426, 564 15
Abstract:
The present invention relates to chimeric chemical compounds which are used to recruit antibodies to cancer cells, in particular, prostate cancer cells or metastasized prostate cancer cells. The compounds according to the present invention comprise an antibody binding terminus (ABT) moiety covalently bonded to a cell binding terminus (CBT) through a linker and optionally, a connector molecule.

Sulfur And Amide Tropolone Inhibitors Of Nucleotidyl Transferases And Uses Therefor

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US Patent:
20220348546, Nov 3, 2022
Filed:
May 3, 2020
Appl. No.:
17/608256
Inventors:
- St. Louis MO, US
- New York NY, US
Maureen Jeanette DONLIN - Kirkwood MO, US
Ryan P. MURELLI - Belleville NJ, US
Assignee:
Saint Louis University - St. Louis MO
Research Foundation of the City University of New York - New York NY
International Classification:
C07D 229/02
C07C 233/58
C07D 295/185
C07D 213/75
C07D 277/22
C07C 233/63
C07D 209/20
C07D 307/68
C07D 333/20
C07D 413/04
C07D 211/26
C07C 233/60
C07D 317/28
C07C 271/22
C07C 311/18
C07D 319/20
C07D 333/34
C07D 271/12
C07D 239/42
C07C 317/24
A61P 31/12
Abstract:
The present disclosure provides inhibitors of microorganisms including viruses and fungi of the formula (I) or (II) wherein the variables are defined herein. Also provided are methods of treatment using these agents in the treatment of infections of microorganisms such as viruses and fungi.

Inhibitors Of Bunyaviridae And Uses Thereof

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US Patent:
20210393548, Dec 23, 2021
Filed:
May 12, 2021
Appl. No.:
17/318329
Inventors:
- St. Louis MO, US
- New York NY, US
- Athens, GR
James BRIEN - St. Louis MO, US
Ryan MURELLI - Belleville NJ, US
Assignee:
Saint Louis University - St. Louis MO
Research Foundation of The City University of New York - New York NY
National and Kapodistrian University of Athens - Athens NY
International Classification:
A61K 31/122
A61K 31/4412
A61K 31/454
A61K 31/341
A61K 31/381
A61K 31/215
A61K 31/165
A61P 31/14
Abstract:
The present disclosure provides inhibitors of bunyavirus of the formula:wherein the variables are defined herein. These inhibitors may be used to treat an infection of Rift Valley phlebovirus, hantavirus, and La Crosse virus, or Crimean-Congo Hemorrhagic fever

Chimeric Small Molecules For The Recruitment Of Antibodies To Cancer Cells

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US Patent:
20200354476, Nov 12, 2020
Filed:
May 22, 2020
Appl. No.:
16/881111
Inventors:
- New Haven CT, US
Ryan Murelli - Belleville NJ, US
Andrew Zhang - Waltham MA, US
International Classification:
C07K 16/44
C07K 16/30
A61K 47/54
A61K 47/68
A61K 31/4192
A61K 45/06
C07D 249/04
A61K 9/00
A61K 47/64
A61K 47/55
Abstract:
The present invention relates to chimeric chemical compounds which are used to recruit antibodies to cancer cells, in particular, prostate cancer cells or metastasized prostate cancer cells. The compounds according to the present invention comprise an antibody binding terminus (ABT) moiety covalently bonded to a cell binding terminus (CBT) through a linker and optionally, a connector molecule.

Chimeric Small Molecules For The Recruitment Of Antibodies To Cancer Cells

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US Patent:
20190127487, May 2, 2019
Filed:
Jul 26, 2018
Appl. No.:
16/045855
Inventors:
- NEW HAVEN CT, US
Ryan Murelli - Belleville NJ, US
Andrew Zhang - Waltham MA, US
International Classification:
C07K 16/44
A61K 9/00
A61K 47/68
A61K 45/06
A61K 31/4192
C07D 249/04
C07K 16/30
A61K 47/54
A61K 47/55
A61K 47/64
Abstract:
The present invention relates to chimeric chemical compounds which are used to recruit antibodies to cancer cells, in particular, prostate cancer cells or metastasized prostate cancer cells. The compounds according to the present invention comprise an antibody binding terminus (ABT) moiety covalently bonded to a cell binding terminus (CBT) through a linker and optionally, a connector molecule.

Anti-Fungal Compounds

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US Patent:
20190099385, Apr 4, 2019
Filed:
Apr 19, 2017
Appl. No.:
16/094682
Inventors:
- St. Louis MO, US
- New york NY, US
Ryan MURELLI - Belleville NJ, US
Marvin J. MEYERS - Wentzville MO, US
Assignee:
SAINT LOUIS UNIVERSITY - St. Louis MO
Research Foundation of the City University of New York - New York NY
International Classification:
A61K 31/122
A61K 31/341
A61K 31/365
A61K 31/381
A61K 31/4418
A61K 31/4375
A61P 31/10
A61K 31/7048
A61K 31/513
A61K 31/4196
A61K 31/496
A61K 31/506
Abstract:
The present disclosure provides compounds of the formula (I), (II), (III), wherein the variables are as defined herein for use in the treatment of fungal infections. In some embodiments, the fungal infection is an infection of fungus. Also provided herein are compositions comprising a compound of formula I, II, or III and a second anti-fungal agent.

Hydroxylated Tropolone Inhibitors Of Nucleotidyl Transferases In Herpesvirus And Hepatitis B And Uses Therefor

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US Patent:
20180297924, Oct 18, 2018
Filed:
Jun 10, 2016
Appl. No.:
15/735195
Inventors:
- St. Louis MO, US
- New York NY, US
Ryan P. MURELLI - Belleville NJ, US
Assignee:
Saint Louis University - St. Louis MO
The City University of New York - New York NY
International Classification:
C07C 49/717
C07C 49/733
C07C 69/757
A61K 9/00
A61P 31/22
Abstract:
The present disclosure relates to inhibitors of herpesvirus nucleic acid metabolism and inhibitors of Hepatitis B virus. Also provided are methods of treatment using these agents.
Ryan P Murelli from Belleville, NJ, age ~43 Get Report