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Ralph Ballerstadt Phones & Addresses

  • 9425 62Nd Ave, Portland, OR 97219 (503) 245-4042

Publications

Us Patents

Device And Method For Measuring Analytes

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US Patent:
8216854, Jul 10, 2012
Filed:
Nov 1, 2006
Appl. No.:
11/591065
Inventors:
Ralph Ballerstadt - Portland OR, US
Roger McNichols - Pearland TX, US
Ashok Gowda - Houston TX, US
Assignee:
BioTex, Inc. - Houston TX
International Classification:
G01N 33/543
US Classification:
436518, 436528, 436535, 436164, 436172, 435 71, 4352831, 4352871, 4352887, 422 50, 422400, 422 681, 422 8205, 422 8208
Abstract:
The present invention is directed to a system, device and method for measuring the concentration of an analyte in a fluid or matrix. A thermodynamically stabilized analyte binding ligand for use in the system, device and method is disclosed. The thermodynamically stabilized analyte binding ligand is resistant to degradation at physiological temperatures and its use within the device provides a minimally invasive sensor for monitoring the concentration of an analyte in a fluid or matrix as are present in the body of an animal.

Methods And Devices For Enhanced Biocompatibility

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US Patent:
20090148493, Jun 11, 2009
Filed:
Dec 5, 2008
Appl. No.:
12/329527
Inventors:
Ralph Ballerstadt - Portland OR, US
George Jackson - Pearland TX, US
Assignee:
BIOTEX, INC. - Houston TX
International Classification:
A61F 2/00
B05D 1/00
A61K 31/7088
A61K 31/7105
A61K 31/711
US Classification:
424423, 427 224, 514 44
Abstract:
The present invention is directed to devices with enhanced biocompatibility and methods for generating and utilizing such devices. The present invention is further directed to enhanced biocompatibility utilizing oligonucleotide functionalization. In one aspect, a device for implantation and/or prolonged exposure to the body tissues includes a functionalized surface. The functionalized surface generally enhances the biocompatibility of the device with body tissues. In some embodiments, the functionalized surface includes substances for controlling interaction between the device and the body tissues. Substances for controlling interactions may include, but are not limited to, polymeric materials, biomolecules, ions and/or ion-releasing substances, and/or any other appropriate substance or combination thereof. In exemplary embodiments, the functionalized surface includes oligonucleotides for controlling interaction between the device and the body tissues. In some exemplary embodiments, the oligonucleotides are aptamers.

Device And Method For Measuring Analytes

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US Patent:
20130034915, Feb 7, 2013
Filed:
Jun 6, 2012
Appl. No.:
13/490392
Inventors:
Ralph Ballerstadt - Portland OR, US
Roger McNichols - Pearland TX, US
Ashok Gowda - Houston TX, US
Assignee:
BIOTEX, INC. - Houston TX
International Classification:
G01N 21/64
G01N 21/63
US Classification:
436501
Abstract:
The present invention is directed to a system, device and method for measuring the concentration of an analyte in a fluid or matrix. A thermodynamically stabilized analyte binding ligand for use in the system, device and method is disclosed. The thermodynamically stabilized analyte binding ligand is resistant to degradation at physiological temperatures and its use within the device provides a minimally invasive sensor for monitoring the concentration of an analyte in a fluid or matrix as are present in the body of an animal.
Ralph D Ballerstadt from Portland, OR Get Report