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Mehmet Hanay Phones & Addresses

  • Ann Arbor, MI
  • 1028 Del Mar Ave, Pasadena, CA 91106 (626) 795-0515
  • La Canada, CA
  • 355 S Marengo Ave APT 310, Pasadena, CA 91101

Work

Position: Professional/Technical

Education

Degree: Associate degree or higher

Publications

Us Patents

Single Molecule Mass Spectroscopy Enabled By Nanoelectromechanical Systems (Nems-Ms)

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US Patent:
20090261241, Oct 22, 2009
Filed:
Jan 23, 2009
Appl. No.:
12/358807
Inventors:
Michael L. ROUKES - Pasadena CA, US
Akshay Naik - Pasadena CA, US
Mehmet Selim Hanay - Pasadena CA, US
International Classification:
H01J 49/26
US Classification:
250282, 250288
Abstract:
The present invention relates to an apparatus for measuring a mass of a sample, using a nanoelectromechanical system (NEMS) arranged to receive the sample added onto a resonator of the NEMS and a microfluidic sample delivery and sample ionization system. The nanoelectromechanical system is located at an output of the ionization system. The nanoelectromechanical resonator system is highly sensitive and is capable of detecting masses in the single Dalton range.

Shape Analysis And Mass Spectrometry Of Individual Molecules By Nanomechanical Systems

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US Patent:
20140244180, Aug 28, 2014
Filed:
Sep 27, 2013
Appl. No.:
14/040294
Inventors:
- Pasedena CA, US
John E. Sader - Victoria, AU
Scott I. Kelber - Pasadena CA, US
Mehmet Selim Hanay - Pasadena CA, US
International Classification:
H01J 49/00
US Classification:
702 19, 702 23
Abstract:
The spatial distribution of mass within an individual analyte can be imaged—in real time and with molecular-scale resolution—when it adsorbs onto a nanomechanical resonator. Each single-molecule adsorption event induces discrete, time-correlated perturbations to the modal frequencies of the device. By continuous monitoring of multiple vibrational modes, the spatial moments of mass distribution can be deduced for individual analytes, one-by-one, as they adsorb. This new method was validated for inertial imaging using both experimental multimode frequency-shift data and finite-element simulations—to analyze the inertial mass, position-of-adsorption, and the shape of individual analytes. Unlike conventional imaging, the spatial resolution of nanomechanical inertial imaging is not limited by wavelength-dependent diffraction phenomena; instead frequency fluctuation processes determine the ultimate attainable resolution. Advanced NEMS devices can provide atomic-scale resolution.

Single-Protein Nanomechanical Mass Spectrometry In Real Time

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US Patent:
20140156224, Jun 5, 2014
Filed:
May 8, 2013
Appl. No.:
13/890087
Inventors:
- Pasadena CA, US
Mehmet Selim HANAY - Pasadena CA, US
Scott KELBER - Pasadena CA, US
Akshay NAIK - Bangalore, IN
Assignee:
California Institute of Technology - Pasadena CA
International Classification:
G01G 9/00
US Classification:
702181, 73865, 702179
Abstract:
Methods and devices relating to measuring a landing position and mass of an analyte adsorbed to a nanomechanical resonator by resolving adsorbate-induced frequency shifts in at least two modes of a resonator resonance frequency, where during the resolving of the frequency shifts in the at least two modes analysis is so that the transformation (G) from the fractional-frequency shift pair to the analyte mass-position pair is one-to-one. Complex protein mixtures can be analyzed at high sensitivity and resolution.
Mehmet S Hanay from Ann Arbor, MI, age ~43 Get Report