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Marlene Mekel Phones & Addresses

  • 1010 Hillsboro Rd, High Ridge, MO 63049 (636) 825-3868
  • Grover, MO
  • 7903 Jessies Way, Hamilton, OH 45011 (513) 674-9791 (513) 868-2925
  • 7903 Jessies Way #302, Hamilton, OH 45011 (513) 868-2925
  • 3953 Ficus Ct, Hamilton, OH 45013 (513) 738-9001
  • Dexter, MI
  • Danville, IL
  • Valley Park, MO
  • Saint Louis, MO
  • 7903 Jessies Way APT 302, Hamilton, OH 45011 (513) 236-7581

Work

Position: Building and Grounds Cleaning and Maintenance Occupations

Education

Degree: Bachelor's degree or higher

Resumes

Resumes

Marlene Mekel Photo 1

Marlene Mekel

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Position:
Research Scientist at Solae
Location:
Greater St. Louis Area
Industry:
Research
Work:
Solae since Jul 2007
Research Scientist

Pfizer Inc. Jun 2006 - Jun 2007
Scientist

Procter & Gamble Jun 1998 - May 2006
Senior Researcher
Education:
Purdue University 1994 - 1998
Skills:
Chromatography
Biochemistry
Protein Purification
Protein Analysis
Protein Characterization
Protein Chemistry
Enzyme Assays
Crystallization
X-ray crystallography
Structural Biology
Immunoassays
Antibodies
Technical Analysis
Technical Writing
Research
Methods Development
Analytics
Analytical Chemistry
R&D
Problem Solving
Biotechnology
Western Blotting
ELISA
Electrophoresis
Marlene Mekel Photo 2

Senior Scientist

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Location:
1501 2Nd St southeast, Waseca, MN 56093
Industry:
Biotechnology
Work:
Washington University School of Medicine
Staff Scientist

Dupont Nutrition & Health Jul 2009 - Mar 2016
Research Scientist

Solae, Llc Jul 2007 - Jul 2009
Research Investigator

Pfizer Jun 2006 - Jun 2007
Scientist

Procter & Gamble Jun 1998 - May 2006
Senior Researcher
Education:
Purdue University 1994 - 1998
Bachelors, Bachelor of Science, Biochemistry
Danville High School 1994
Skills:
Protein Chemistry
Biochemistry
R&D
Chromatography
Analytical Chemistry
Chemistry
Protein Purification
Assay Development
Microbiology
Research
Biotechnology
Elisa
Spectroscopy
Life Sciences
Immunoassays
Enzyme Assays
Western Blotting
Lc Ms
Protein Crystallization
Sds Page
X Ray Crystallography
Team Leadership
Research and Development
Cross Functional Team Leadership
Protein Analysis
Protein Characterization
Crystallization
Structural Biology
Antibodies
Technical Analysis
Technical Writing
Methods Development
Analytics
Problem Solving
Electrophoresis
Lifesciences

Publications

Us Patents

Crystal Of Hypoxia Inducible Factor 1 Alpha Prolyl Hydroxylase

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US Patent:
8050873, Nov 1, 2011
Filed:
May 28, 2009
Appl. No.:
12/473536
Inventors:
Artem Gennady Evdokimov - Loveland OH, US
Richard Masaru Kawamoto - Lebanon OH, US
Angelique Sun Boyer - West Chester OH, US
Marlene Jan Mekel - Ross OH, US
Matthew Eugene Pokross - Hamilton OH, US
Assignee:
Warner Chilcott Company - Fajardo PR
International Classification:
G01N 31/00
G01N 33/567
G06G 7/58
C12Q 1/26
US Classification:
702 27, 703 11, 435 25, 435 721
Abstract:
The crystal structure of ligand-bound EGLN1 catalytic domain of prolyl hydroxylase is disclosed. These coordinates are useful in computer aided drug design for identifying compounds that regulate EGLN1 prolyl hydroxylase and thereby regulate HIF-regulated disorders.

Crystal Of Hypoxia Inducible Factor 1 Alpha Prolyl Hydroxylase

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US Patent:
8512972, Aug 20, 2013
Filed:
Sep 12, 2011
Appl. No.:
13/230548
Inventors:
Artem Gennady Evdokimov - Loveland OH, US
Richard Masaru Kawamoto - Lebanon OH, US
Angelique Sun Boyer - West Chester OH, US
Marlene Jan Mekel - Ross OH, US
Matthew Eugene Pokross - Hamilton OH, US
Assignee:
Akebia Therapeutics, Inc. - Cincinnati OH
International Classification:
C12Q 1/26
G01N 31/00
G06G 7/58
US Classification:
435 25, 702 27, 703 11, 703 12
Abstract:
The crystal structure of ligand-bound EGLN1 catalytic domain of prolyl hydroxylase is disclosed. These coordinates are useful in computer aided drug design for identifying compounds that regulate EGLN1 prolyl hydroxylase and thereby regulate HIF-regulated disorders.

Methods Of Formulating Enzyme Cocktails, Enzyme Cocktails For The Removal Of Egg-Based And Grass-Based Stains And/Or Soils, Compositions And Products Comprising Same

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US Patent:
20050059567, Mar 17, 2005
Filed:
Sep 11, 2003
Appl. No.:
10/660312
Inventors:
Michael Showell - Cincinnati OH, US
Hiroshi Oh - Cincinnati OH, US
Anna Radomyselski - Hamilton OH, US
Alison Main - Tyne & Wear, GB
Anju Brooker - Newcastle Upon Tyne, GB
Andrew Nelson - Newcastle Upon Tyne, GB
Yiping Sun - West Chester OH, US
William Begley - Tipp City OH, US
Larry Smith - Cincinnati OH, US
Richard Walter - Hamilton OH, US
Marlene Mekel - Hamilton OH, US
International Classification:
C11D003/00
US Classification:
510392000
Abstract:
Methods of formulating enzyme cocktails based on the presence of enzyme-hydrolysable components in a target stain and/or soil. More specifically, the formulation of an enzyme cocktail comprising a specific enzyme for each component in a target stain and/or soil, optionally wherein each enzyme is incorporated at a level corresponding to the level of an enzyme-hydrolysable component in said target stain and/or soil. Further, enzyme cocktails for removing egg-based and grass-based stains, optionally formulated in accordance with the methods disclosed herein. Moreover, compositions and products comprising the enzyme cocktails disclosed herein and methods of using same.

Methods Of Formulating Enzyme Cocktails, Enzyme Cocktails For The Removal Of Egg-Based And Grass-Based Stains And/Or Soils, Compositions And Products Comprising Same

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US Patent:
20060172913, Aug 3, 2006
Filed:
Mar 31, 2006
Appl. No.:
11/395792
Inventors:
Michael Showell - Cincinnati OH, US
Hiroshi Oh - Cincinnati OH, US
Anna Radomyselski - Hamilton OH, US
Allison Main - Tyne & Wear, GB
Anju Deepali Brooker - Newcastle Upon Tyne, GB
Andrew Nelson - Wear, GB
Yiping Sun - West Chester OH, US
William Begley - Tipp City OH, US
Larry Smith - Cincinnati OH, US
Richard Walter - Hamilton OH, US
Marlene Mekel - Hamilton OH, US
International Classification:
C11D 3/00
US Classification:
510392000
Abstract:
Methods of formulating enzyme cocktails based on the presence of enzyme-hydrolysable components in a target stain and/or soil. More specifically, the formulation of an enzyme cocktail comprising a specific enzyme for each component in a target stain and/or soil, optionally wherein each enzyme is incorporated at a level corresponding to the level of an enzyme-hydrolysable component in said target stain and/or soil. Further, enzyme cocktails for removing egg-based and grass-based stains, optionally formulated in accordance with the methods disclosed herein. Moreover, compositions and products comprising the enzyme cocktails disclosed herein and methods of using same.

Three Dimensional Coordinates Of Hypoxia Inducible Factor 1 Alpha (Hif-1 Alpha)-Prolyl Hydroxylase (Egln1) And Uses Thereof

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US Patent:
20080124740, May 29, 2008
Filed:
Mar 5, 2007
Appl. No.:
11/713941
Inventors:
Artem Gennady Evdokimov - Loveland OH, US
Richard Masaru Kawamoto - Lebanon OH, US
Angelique Sun Boyer - West Chester OH, US
Marlene Jan Mekel - Ross OH, US
Matthew Eugene Pokross - Hamilton OH, US
Richard Lee Walter - Hamilton OH, US
International Classification:
G01N 33/566
US Classification:
435 78
Abstract:
The crystal structure of ligand-bound EGLN1 catalytic domain of prolyl hydroxylase is disclosed. These coordinates are useful in computer aided drug design for identifying compounds that regulate EGLN1 prolyl hydroxylase and thereby regulate HIF-regulated disorders.

Purified Kunitz Trypsin Inhibitor Proteins Isolated From A Soy Processing Stream

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US Patent:
20120289683, Nov 15, 2012
Filed:
Dec 30, 2010
Appl. No.:
13/519848
Inventors:
Charles S. Schasteen - University City MO, US
Darrell Marsh - High Ridge MO, US
Karsten Keller - Hockessin DE, US
Barry Tulk - Creve Coeur MO, US
Marlene Mekel - High Ridge MO, US
Jennifer Wu - St. Charles MO, US
Assignee:
SOLAE, LLC - ST LOUIS MO
International Classification:
C07K 14/81
US Classification:
530350
Abstract:
A novel Kunitz-trypsin Inhibitor (KTI) isoform recovered from a processing stream and that has a total KTI protein concentration of at least about 95 wt. % is disclosed, as well as a process for recovering and isolating the purified KTI isoform from a processing stream.

Method For Recovering Bowman-Birk Inhibitor Proteins From A Soy Processing Stream

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US Patent:
20120302736, Nov 29, 2012
Filed:
Dec 30, 2010
Appl. No.:
13/519840
Inventors:
Darrell Marsh - High Ridge MO, US
Charles S. Schasteen - University City MO, US
Barry Tulk - Creve Coeur MO, US
Karsten Keller - Creve Coeur MO, US
Jennifer Wu - St. Charles MO, US
Marlene Mekel - High Ridge MO, US
International Classification:
C07K 1/16
C07K 14/415
US Classification:
530378
Abstract:
The present invention describes novel methods for purifying a BBI product having a total specified BBI protein concentration and other characteristics of BBI (including, for example, chymotrypsin inhibitor activity and endotoxin content).

Soy Whey Protein Compositions And Methods For Recovering Same

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US Patent:
20120329993, Dec 27, 2012
Filed:
Dec 30, 2010
Appl. No.:
13/519829
Inventors:
Darrell Marsh - High Ridge MO, US
Karsten Keller - Hockessin DE, US
Charles S. Schasteen - University City MO, US
Barry Tulk - Creve Coeur MO, US
Marlene Mekel - High Ridge MO, US
Jennifer Wu - ST. Charles MO, US
Assignee:
LEGAL DEPARTMENT - ST. LOUIS MO
International Classification:
C07K 14/415
C12S 3/14
US Classification:
530370, 435272
Abstract:
A process for recovering and isolating soy whey proteins and other components from whey processing streams is disclosed.
Marlene J Mekel from High Ridge, MO, age ~49 Get Report