Inventors:
Albee Messing - Madison WI
Lang Zhuo - Middleton WI
Assignee:
Wisconsin Alumni Research Foundation - Madison WI
International Classification:
A61K 6700
Abstract:
A transgenic mammal, specifically a mouse, containing in its genome a humanized mutant of green fluorescent protein operably linked to the glial fibrillary acidic protein promoter is provided. The mouse can be used to assay the effects of systemic or topical administration of neurotoxins and also to assay the effects of physical damage to neural tissue.