Jonathan A Pevsner

50307223, Jul 9, 1991

Mar 30, 1988

7/175180

Solomon H. Snyder - Baltimore MD
Jonathan Pevsner - Baltimore MD
Randall Reed - Baltimore MD

The Johns Hopkins University - Baltimore MD

C12N 1500
C12P 2100
C07H 1512

536 27

DNA molecules are taught which code for an odorant-binding protein which is synthesized solely in the lateral nasal gland. This protein, because of the broad range of odorants which it binds, can be used in many techniques for trapping odorants in either a liquid or solid medium. This protein bears some structural homology with other carriers of small lipophilic molecules from many other species; the carriers are known to transport specific lipophilic molecules.

52602702, Nov 9, 1993

Jul 15, 1991

7/730074

Solomon H. Snyder - Baltimore MD
Jonathan Pevsner - Baltimore MD
Randall Reed - Baltimore MD

The Johns Hopkins University - Baltimore MD

A61K 3702
C07K 1300

514 2

DNA molecules are taught which code for an odorant-binding protein which is synethesized solely in the lateral nasal gland. This protein, because of the broad range of odorants which it binds, can be used in many techniques for trapping odorants in either a liquid or solid medium. This protein bears some structural homology with other carriers of small lipophilic molecules from many other species; the carriers are known to transport specific lipophilic molecules.

51282461, Jul 7, 1992

Mar 13, 1990

7/492792

Solomon H. Snyder - Baltimore MD
Jonathan Pevsner - Baltimore MD
Randall Reed - Baltimore MD

The Johns Hopkins University - Baltimore MD

C12N 1512
G12P 2102

435 691

DNA molecules are taught which code for an odorant-binding protein which is synthesized solely in the lateral nasal gland. This protein, because of the broad range of odorants which it binds, can be used in many techniques for trapping odorants in either a liquid or solid medium. This protein bears some structural homology with other carriers of small lipophilic molecules from many other species; the carriers are known to transport specific lipophilic molecules.

20200232033, Jul 23, 2020

Aug 28, 2019

16/553843

- Baltimore MD, US
Jonathan Pevsner - Baltimore MD, US

C12Q 1/6881
C12Q 1/6858

The present invention provides methods for analyzing blocks of closely spaced SNPs, or haplotypes for use in identification of the origin of DNA in a sample. The methods comprise aligning common alleles of a gene of interest and identifying a region containing a plurality of SNPs which is flanked by non-polymorphic DNA which can be used for primer placement. Any sequencing method, including next generation sequencing methods can then be used to determine the haplotypes in the sample with a lower limit of detection of at least 0.01%. These inventive methods are useful, for example, for identification of hematopoietic stem cell transplantation patients destined to relapse, microchimerism associated with solid organ transplantation, detection of solid organ transplant rejection by detecting donor DNA in recipient plasma, forensic applications, and patient identification.

20170218447, Aug 3, 2017

Aug 5, 2015

15/500736

- Baltimore MD, US
Jonathan Pevsner - Baltimore MD, US

C12Q 1/68

The present invention provides methods for analyzing blocks of closely spaced SNPs, or haplotypes for use in identification of the origin of DNA in a sample. The methods comprise aligning common alleles of a gene of interest and identifying a region containing a plurality of SNPs which is flanked by non-polymorphic DNA which can be used for primer placement. Any sequencing method, including next generation sequencing methods can then be used to determine the haplotypes in the sample with a lower limit of detection of at least 0.01%. These inventive methods are useful, for example, for identification of hematopoietic stem cell transplantation patients destined to relapse, microchimerism associated with solid organ transplantation, detection of solid organ transplant rejection by detecting donor DNA in recipient plasma, forensic applications, and patient identification.