Jens Gundlach Phones & Addresses
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13900 Northwood Rd NW, Seattle, WA 98177 (206) 364-2447
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2815 Montlake Blvd E, Seattle, WA 98112 (206) 324-8577
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Lopez Island, WA
Business Records
Name / Title
Company / Classification
Phones & Addresses
Board of Directors
University of Washington
College/University
College/University
1900 Commerce St, Tacoma, WA 98402
(253) 692-4000
(253) 692-4000
Publications
Wikipedia References
Jens H. Gundlach
Us Patents
Interferometric Quasi-Autocollimator
View pageUS Patent:
20120242999, Sep 27, 2012
Filed:
Mar 21, 2012
Appl. No.:
13/426309
Inventors:
Matthew D. Turner - Seattle WA, US
Jens H. Gundlach - Seattle WA, US
Charles A. Hagedorn - Seattle WA, US
Stephan Schlamminger - Rockville MD, US
Jens H. Gundlach - Seattle WA, US
Charles A. Hagedorn - Seattle WA, US
Stephan Schlamminger - Rockville MD, US
Assignee:
University of Washington through its Center for Commercialization - Seattle WA
International Classification:
G01B 9/02
US Classification:
356491, 356450
Abstract:
Systems and method are disclosed for measuring small angular deflections of a target using weak value amplification. A system includes a beam source, a beam splitter, a target reflecting surface, a photodetector, and a processor. The beam source generates an input beam that is split into first and second beams by the beam splitter. The first and second beams are propagated to the target reflecting surface, at least partially superimposed at the target reflecting surface, and incident to the target reflecting surface normal to the target reflecting surface. The first beam is reflected an additional even number of times during propagation to the photodetector. The second beam is reflected an additional odd number of times during propagation to the photodetector. The first and second beams interfere at the photodetector so as to produce interference patterns. The interference patterns are interpreted to measure angular deflections of the target reflecting surface.
Artificial Mycolic Acid Membranes
View pageUS Patent:
20130146456, Jun 13, 2013
Filed:
Aug 22, 2012
Appl. No.:
13/592030
Inventors:
Jens Gundlach - Seattle WA, US
Ian M. Derrington - Seattle WA, US
Kyle W. Langford - University Place WA, US
Ian M. Derrington - Seattle WA, US
Kyle W. Langford - University Place WA, US
Assignee:
UNIVERSITY OF WASHINGTON - Seattle WA
International Classification:
G01N 27/447
US Classification:
204451, 554213, 554219, 554115, 252184
Abstract:
Provided herein are artificial membranes of mycolic acids. The membranes may be unsupported or tethered. These membranes are long lived and highly resistant to electroporation, demonstrating their general strength. The mycolic acid membranes are suitable for controlled studies of the mycobacterial outer membrane and can be used in other experiments, such as nanopore analyte translocation experiments.
Analyte Sequencing With Nanopores
View pageUS Patent:
20130146457, Jun 13, 2013
Filed:
Aug 22, 2012
Appl. No.:
13/592077
Inventors:
Jens Gundlach - Seattle WA, US
Ian M. Derrington - Seattle WA, US
Marcus D. Collins - Issaquah WA, US
Ian M. Derrington - Seattle WA, US
Marcus D. Collins - Issaquah WA, US
Assignee:
UNIVERSITY OF WASHINGTON - Seattle WA
International Classification:
G01N 27/447
US Classification:
204451, 204601, 977781, 977924
Abstract:
Provided herein are methods and systems pertaining to sequencing units of analytes using nanopores. In general, arresting constructs are used to modify an analyte such that the modified analyte pauses in the opening of a nanopore. During such a pause, an ion current level is obtained that corresponds to a unit of the analyte. After altering the modified analyte such that the modified analyte advances through the opening, another arresting construct again pauses the analyte, allowing for a second ion current level to be obtained that represents a second unit of the analyte. This process may be repeated until each unit of the analyte is sequenced. Systems for performing such methods are also disclosed.
Msp Nanopores And Related Methods
View pageUS Patent:
20120055792, Mar 8, 2012
Filed:
Mar 22, 2011
Appl. No.:
13/069187
Inventors:
Jens H. GUNDLACH - Seattle WA, US
Michael NIEDERWEIS - Homewood AL, US
Thomas Z. BUTLER - Seattle WA, US
Mikhail PAVLENOK - Birmingham AL, US
Mark A. TROLL - Seattle WA, US
Michael NIEDERWEIS - Homewood AL, US
Thomas Z. BUTLER - Seattle WA, US
Mikhail PAVLENOK - Birmingham AL, US
Mark A. TROLL - Seattle WA, US
Assignee:
THE UAB RESEARCH FOUNDATION - Birmingham AL
UNIVERSITY OF WASHINGTON - Seattle WA
UNIVERSITY OF WASHINGTON - Seattle WA
International Classification:
C07K 14/35
C12N 15/63
C12N 1/21
G01N 27/447
C25B 7/00
C12N 15/31
C12P 21/00
B82Y 30/00
B82Y 40/00
C12N 15/63
C12N 1/21
G01N 27/447
C25B 7/00
C12N 15/31
C12P 21/00
B82Y 30/00
B82Y 40/00
US Classification:
204450, 530350, 536 237, 4353201, 4352523, 435 691, 204600, 204601, 977840, 977780
Abstract:
Provided herein are porin nanopores, systems that comprise these nanopores, and methods of using and making these nanopores. Such nanopores may be wild-type MspA porins, mutant MspA porins, wild-type MspA paralog porins, wild-type MspA homolog porins, mutant MspA paralog porins, mutant MspA homolog porins, or single-chain Msp porins. Also provided are bacterial strains capable of inducible Msp porin expression.
Device For Sequencing
View pageUS Patent:
20220299469, Sep 22, 2022
Filed:
May 31, 2022
Appl. No.:
17/828991
Inventors:
- San Diego CA, US
Jens Gundlach - Seattle WA, US
Jens Gundlach - Seattle WA, US
International Classification:
G01N 27/414
G01N 33/487
H01L 21/74
H01L 29/66
H01L 29/786
G01N 33/487
H01L 21/74
H01L 29/66
H01L 29/786
Abstract:
Example devices include a cis well associated with a cis electrode, a trans well associated with a trans electrode, and a field effect transistor (FET) positioned between the cis well and the trans well. Examples of the field effect transistor (FET) include a fluidic system defined therein. The fluidic system includes a first cavity facing the cis well, a second cavity fluidically connected to the trans well, and a through via extending through the field effect transistor from the first cavity. A first nanoscale opening fluidically connects the cis well and the first cavity, the first nanoscale opening having an inner diameter. A second nanoscale opening fluidically connects the through via and the second cavity, the second nanoscale opening having an inner diameter. The second nanoscale opening inner diameter is larger than the first nanoscale opening inner diameter.
Compositions, Systems, And Methods For Detecting Events Using Tethers Anchored To Or Adjacent To Nanopores
View pageUS Patent:
20220251641, Aug 11, 2022
Filed:
Feb 18, 2022
Appl. No.:
17/675264
Inventors:
- San Diego CA, US
Kevin L. Gunderson - Encinitas CA, US
Jens H. Gundlach - Seattle WA, US
Kevin L. Gunderson - Encinitas CA, US
Jens H. Gundlach - Seattle WA, US
International Classification:
C12Q 1/6869
G01N 27/447
G01N 27/447
Abstract:
Compositions, systems, and methods for detecting events are provided. A composition can include a nanopore including a first side, a second side, and an aperture extending through the first and second sides; and a permanent tether including head and tail regions and an elongated body disposed there between. The head region can be anchored to or adjacent to the first or second side of the nanopore. The elongated body including a reporter region can be movable within the aperture responsive to a first event occurring adjacent to the first side of the nanopore. For example, the reporter region is translationally movable toward the first side responsive to the first event, then toward the second side, then toward the first side responsive to a second event. The first event can include adding a first nucleotide to a polynucleotide. The second event can include adding a second nucleotide to the polynucleotide.
Compositions And Methods For Polynucleotide Sequencing
View pageUS Patent:
20210355534, Nov 18, 2021
Filed:
May 25, 2021
Appl. No.:
17/329482
Inventors:
- San Diego CA, US
Jens H. Gundlach - Seattle WA, US
Jeffrey G. Mandell - La Jolla CA, US
Kevin L. Gunderson - Encinitas CA, US
Ian M. Derrington - Seattle WA, US
Hosein Mohimani - San Diego CA, US
Jens H. Gundlach - Seattle WA, US
Jeffrey G. Mandell - La Jolla CA, US
Kevin L. Gunderson - Encinitas CA, US
Ian M. Derrington - Seattle WA, US
Hosein Mohimani - San Diego CA, US
International Classification:
C12Q 1/6869
G01N 27/447
C07K 14/35
G01N 27/447
C07K 14/35
Abstract:
Methods and compositions for characterizing a target polynucleotide, including, characterizing the sequence of the target polynucleotide, using the fractional translocation steps of the target polynucleotide's translocation through a pore.
Device For Sequencing
View pageUS Patent:
20210156819, May 27, 2021
Filed:
Feb 13, 2019
Appl. No.:
16/626011
Inventors:
- San Diego CA, US
Jens Gundlach - Seattle WA, US
Jens Gundlach - Seattle WA, US
International Classification:
G01N 27/414
H01L 29/786
H01L 29/66
H01L 21/74
G01N 33/487
H01L 29/786
H01L 29/66
H01L 21/74
G01N 33/487
Abstract:
Example devices include a cis well associated with a cis electrode, a trans well associated with a trans electrode, and a field effect transistor (FET) positioned between the cis well and the trans well. Examples of the field effect transistor (FET) include a fluidic system defined therein. The fluidic system includes a first cavity facing the cis well, a second cavity fluidically connected to the trans well, and a through via extending through the field effect transistor from the first cavity. A first nanoscale opening fluidically connects the cis well and the first cavity, the first nanoscale opening having an inner diameter. A second nanoscale opening fluidically connects the through via and the second cavity, the second nanoscale opening having an inner diameter. The second nanoscale opening inner diameter is larger than the first nanoscale opening inner diameter.