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Ingrid D Mergelsberg

from Mahwah, NJ
Age ~70
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Related to:
Manfred M Mergelsberg, 72
Connected to:
Akaesha B Mergen, 37Anne B Mergen, 114Carol M Mergen, 83Cengiz Mergen, 92Donna R Mergen, 70Frederic Mergen, 52George R Mergen, 68Eric S Mergener, 41Gaylynn Mergener, 57Lori M Mergener, 52

Ingrid Mergelsberg Phones & Addresses

  • 9 Oweno Pl, Mahwah, NJ 07430 (201) 252-2187
  • Watchung, NJ
  • Berlin, NJ
  • 9 Oweno Pl, Mahwah, NJ 07430

Work

Position: Professional/Technical

Education

Degree: Associate degree or higher

Emails

m***[email protected]

Publications

Us Patents

Process For Preparing Substituted 8-Azabicyclo[3.2.1]Octan-3-Ols

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US Patent:
7459556, Dec 2, 2008
Filed:
Sep 13, 2005
Appl. No.:
11/225244
Inventors:
Ingrid Mergelsberg - Watchung NJ, US
Gerald Werne - Kriens, CH
Assignee:
Schering-Plough Ltd. - Lucerne
International Classification:
C07D 239/02
C07D 451/02
C07D 401/00
C07D 405/00
C07D 409/00
C07D 411/00
C07D 413/00
C07D 417/00
US Classification:
544335, 546124, 546125, 546126, 546127
Abstract:
The present invention relates to a process for preparing substituted 8-azabicyclo[3. 2. 1]octan-3-ols having the structural formula I.

Hydrochloride Salts Of 8-[{1-(3,5-Bis-(Trifluoromethyl)Phenyl)-Ethoxy)-Methyl]-8-Phenyl-1,7-Diaza-Spiro[4.5]Decan-2-One And Preparation Process Therefor

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US Patent:
8178550, May 15, 2012
Filed:
Apr 4, 2007
Appl. No.:
11/732548
Inventors:
Mengwei Hu - Washington NJ, US
Sunil Paliwal - Monroe Township NJ, US
Neng-Yang Shih - Warren NJ, US
Frank Bruno Guenter - Schachen, CH
Ingrid Mergelsberg - Mahwah NJ, US
Assignee:
OPKO Health, Inc. - Miami FL
International Classification:
A01N 43/42
A61K 31/44
C07D 215/00
C07D 217/00
C07D 219/00
C07D 221/00
US Classification:
514278, 546 16
Abstract:
Disclosed are hydrochloride and tosylate crystalline salt forms of (5S,8S)-8-[{(1R)-1-(3,5-Bis-(trifluoromethyl)phenyl)-ethoxy}-methyl]-8-phenyl-1,7-diazaspiro[4. 5]decan-2-one, represented by Formula I and methods of preparing the same.

Hydrochloride Salts Of 8-[{1-(3,5-Bis-Trifluoromethyl)Phenyl)-Ethoxy}-Methyl]-8-Phenyl-1,7-Diaza-Spiro[4.5]Decan-2-One And Preparation Process Therefor

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US Patent:
8470842, Jun 25, 2013
Filed:
Nov 6, 2009
Appl. No.:
12/614108
Inventors:
Mengwei Hu - Washington NJ, US
Sunil Paliwal - Monroe Township NJ, US
Neng-Yang Shih - Lexington MA, US
Frank Bruno Guenter - Schachen, CH
Ingrid Mergelsberg - Mahwah NJ, US
Assignee:
OPKO Health, Inc. - Miami FL
International Classification:
A01N 43/42
A61K 31/44
C07D 215/00
C07D 217/00
C07D 219/00
C07D 221/00
US Classification:
514278, 546 16
Abstract:
Disclosed are hydrochloride and tosylate crystalline salt forms of (5S,8S)-8-[{(1R)-1-(3,5-Bis-(trifluoromethyl)phenyl)-ethoxy}-methyl]-8-phenyl-1,7-diazaspiro[4. 5]decan-2-one, represented by Formula I and methods of preparing the same.

Process And Intermediates For The Synthesis Of 8-[{1-(3,5-Bis-(Trifluoromethyl)Phenyl)-Ethoxy}-Methyl]-8-Phenyl-1,7-Diaza-Spiro[4.5]Decan-2-One Compounds

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US Patent:
8552191, Oct 8, 2013
Filed:
Mar 20, 2008
Appl. No.:
12/531859
Inventors:
Ingrid Mergelsberg - Mahwah NJ, US
Dominik Hermann Scherer - Horw, CH
Monika Erika Huttenloch - Kriens, CH
Sunil Paliwal - Monroe Township NJ, US
Neng-Yang Shih - Lexington MA, US
Assignee:
Opko Health, Inc. - Miami FL
International Classification:
C07D 221/20
US Classification:
546 16, 546223
Abstract:
This application discloses a novel process to synthesize 8-[{1-(3,5-Bis-(trifluoromethyl)phenyl)-ethoxy}-methyl]-8-phenyl-1,7-diaza-spiro[4. 5]decan-2-one compounds, which may be used, for example, as NK-1 inhibitor compounds in pharmaceutical preparations.

Hydrochloride Salts Of 8-[1-(3,5-Bis-(Trifluoromethyl)Phenyl)-Ethoxymethyl]-8-Phenyl-1,7-Diazaspiro[4,5]Decan-2-One And Preparation Process Therefor

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US Patent:
20130281477, Oct 24, 2013
Filed:
Jun 21, 2013
Appl. No.:
13/923859
Inventors:
Sunil Paliwal - Monroe Township NJ, US
Neng-Yang Shih - Lexington MA, US
Frank Bruno Guenter - Schachen, CH
Ingrid Mergelsberg - Mahwah NJ, US
International Classification:
C07D 471/10
A61K 31/495
A61K 31/435
US Classification:
514278, 546 16
Abstract:
Disclosed are hydrochloride and tosylate crystalline salt forms of (5S,8S)-8-[{(1R)-1-(3,5-Bis-(trifluoromethyl)phenyl)-ethoxy}-methyl]-8-phenyl-1,7-diazaspiro[4.5]decan-2-one, represented by Formula I and methods of preparing the same.

Process And Intermediates For The Synthesis Of 8-[-Methyl]-8-Phenyl-1,7-Diaza-Spiro[4.5]Decan-2-One Compounds

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US Patent:
20140031549, Jan 30, 2014
Filed:
Oct 1, 2013
Appl. No.:
14/043210
Inventors:
Gerald Werne - Ketsch, DE
Xiaoyong Fu - Edison NJ, US
Robert K. Orr - Cranford NJ, US
Frank Xing Chen - Plainsboro NJ, US
Jian Cui - Edison NJ, US
Victoria M. Sprague - Bridgewater NJ, US
Fucheng Zhang - Edison NJ, US
Ji Xie - Edison NJ, US
Liansheng Zeng - Union NJ, US
Louis Peter Castellanos - Union City NJ, US
Yuyin Chen - Garwood NJ, US
Marc Poirier - Stewartsville NJ, US
Ingrid Mergelsberg - Mahwah NJ, US
Assignee:
OPKO Health, Inc. - Miami FL
International Classification:
C07D 471/10
C07D 207/267
C07C 217/48
C07D 498/04
US Classification:
546 16, 548217, 548530, 564346, 548550
Abstract:
This application discloses a novel process to synthesize 8-[{1-(3,5-Bis-(trifluoromethyl)phenyl)-ethoxy}-methyl]-8-phenyl-1,7-diaza-spiro[4.5]decan-2-one compounds, which may be used, for example, as NK-1 inhibitor compounds in pharmaceutical preparations, intermediates useful in said process, and processes for preparing said intermediates; also disclosed is a process for removal of metals from N-heterocyclic carbine metal complexes.

Hydrochloride Salts Of 8-[{1-(3,5-Bis-(Trifluoromethyl)Phenyl)-Ethoxy}-Methyl]-8-Phenyl-1,7-Diaza-Spiro[4.5]Decan-2-One And Preparation Process Therefor

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US Patent:
20190375751, Dec 12, 2019
Filed:
Jan 9, 2019
Appl. No.:
16/243404
Inventors:
- Miami FL, US
Sunil Paliwal - Monroe Township NJ, US
Neng-Yang Shih - Warren NJ, US
Frank Bruno Guenter - Schachen, CH
Ingrid Mergelsberg - Mahwah NJ, US
Assignee:
OPKO Health, Inc. - Miami FL
International Classification:
C07D 471/10
A61K 45/06
A61K 31/495
A61K 31/435
Abstract:
Disclosed are hydrochloride and tosylate crystalline salt forms of (5S,8S)-8-[{(1R)-1-(3,5-Bis-(trifluoromethyl)phenyl)-ethoxy}-methyl]-8-phenyl-1,7-diazaspiro[4.5]decan-2-one, represented by Formula I and methods of preparing the same.

Process And Intermediates For The Synthesis Of 8-[-Methyl]-8-Phenyl-1,7-Diaza-Spiro[4.5]Decan-2-One Compounds

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US Patent:
20160145256, May 26, 2016
Filed:
Feb 1, 2016
Appl. No.:
15/012422
Inventors:
- Miami FL, US
Gerald Werne - Ketsch, DE
Xiaoyong Fu - Edison NJ, US
Robert K. Orr - Cranford NJ, US
Frank Xing Chen - Plainsboro NJ, US
Jian Cui - Edison NJ, US
Victoria M. Sprague - Bridgewater NJ, US
Fucheng Zhang - Edison NJ, US
Ji Xie - Edison NJ, US
Liansheng Zeng - Union NJ, US
Louis Peter Castellanos - Union City NJ, US
Yuyin Chen - Garwood NJ, US
Marc Poirier - Stewartsville NJ, US
Ingrid Mergelsberg - Mahwah NJ, US
International Classification:
C07D 471/10
C07D 207/267
C07C 217/46
C07D 498/04
C07D 207/28
Abstract:
This application discloses a novel process to synthesize 8-[{1-(3,5-Bis-(trifluoromethyl)phenyl)-ethoxy}-methyl]-8-phenyl-1,7-diaza-spiro[4.5]decan-2-one compounds, which may be used, for example, as NK-1 inhibitor compounds in pharmaceutical preparations, intermediates useful in said process, and processes for preparing said intermediates; also disclosed is a process for removal of metals from N-heterocyclic carbine metal complexes.
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Ingrid D Mergelsberg from Mahwah, NJ, age ~70 Get Report