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Huixian Tang

from San Diego, CA
Age ~62
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Also known as:
Hui Xian Tang, Huixian Zhou
Phone and address:
8124 Via Kino, San Diego, CA 92122
(858) 558-8909
Related to:
Yong Zhou, 55Lingyue ZhouYiming Zhao, 39Darin ZhouZhang YongeYing Zhang, 98Lingbo Zhou
Connected to:
Aaron Tang, 53Adrian Y Tang, 54Alana M Tang, 26Allan K Tang, 58Ally H Tang, 34Aly H Tang, 56America Tang, 69Anli Tang, 33Anlun Tang, 63Benjamin W Tang, 58

Huixian Tang Phones & Addresses

  • 8124 Via Kino, San Diego, CA 92122 (858) 558-8909
  • 8124 Via Kino #1, San Diego, CA 92122 (858) 558-8909
  • 8030 Regents Rd, San Diego, CA 92122 (858) 558-8909
  • 9515 Genesee Ave, San Diego, CA 92121 (858) 558-8909
  • Highland Park, NJ
  • Piscataway, NJ

Resumes

Resumes

Huixian Tang Photo 1

Senior Scientist

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Location:
San Diego, CA
Industry:
Biotechnology
Work:
Bps Bioscience Inc.
Senior Scientist
Senomyx Jan 2013 - Jan 2015
Scientist
Senomyx Jan 2005 - Dec 2012
Associate Scientist
Senomyx Aug 2000 - Dec 2004
Senior Research Associate
Ciblex Corporation Sep 1998 - Aug 2000
Senior Research Associate
Education:
Nanjing Agricultural University
Bachelors, Biology Chinese Academy of Agricultural Sciences, Beijing
Masters, Biology
Skills:
High Throughput Screening
Assay Development
Cell Biology
Molecular Biology
Gpcrs
Biotechnology
Life Sciences
Drug Discovery
Cell Culture
Stable Cell Lines
Cell Culture and Transfection
Cell
Western Blotting
Protein Engineering
Elisa
Ion Channels
Biochemistry
Facs
Calcium Imaging
Huixian Tang Photo 2

Huixian Tang

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Publications

Us Patents

Human T2R Receptors For Acetaminophen Ranitidine, Strychnine And Denatomium And Related Assays For Identifying Human Bitter Taste Modulators

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US Patent:
7407765, Aug 5, 2008
Filed:
Jan 26, 2006
Appl. No.:
11/339553
Inventors:
Xiaodong Li - Oceanside CA, US
Hong Xu - San Diego CA, US
Huixian Tang - San Diego CA, US
Qing Li - San Diego CA, US
Assignee:
Senomyx, Inc. - La Jolla CA
International Classification:
G01N 33/566
C07K 14/705
US Classification:
435 71, 435 72, 435 721, 436501
Abstract:
The present invention relates to the discovery that specific human taste receptors in the T2R taste receptor family respond to particular bitter ligands, i. e. , acetaminophen, ranitidine, strychnine and denatonium. The present invention further relates to the use of these receptors in assays for identifying ligands that modulate the activation of these taste receptors and which may be used as additives in foods, beverages and medicinals for modifying (blocking) T2R-associated bitter taste.

Nucleic Acid Sequences Encoding A Bitter Taste Receptor, T2R76

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US Patent:
7517972, Apr 14, 2009
Filed:
Jul 29, 2003
Appl. No.:
10/628464
Inventors:
Jon Elliot Adler - San Diego CA, US
Huixian Tang - San Diego CA, US
Alexey Pronin - San Diego CA, US
Assignee:
Senomyx, Inc. - San Diego CA
International Classification:
C07H 21/04
C12N 15/63
C12N 1/19
C12N 1/21
C12N 5/16
C12N 5/22
US Classification:
536 235, 4352523, 4352542, 4353201, 435325, 435348, 435364, 435365, 435367, 435369
Abstract:
Isolated nucleic acids encoding T2R76 polypeptides, recombinantly expressed T2R76 polypeptides, heterologous expression systems for recombinant expression of T2R76 polypeptides, assay methods employing the same, and methods for altering taste perception via administration of a T2R76 modulator. These T22R76 polypeptides can be expressed alone or co-expressed with another T2R polypeptide, preferably a different human T2R polypeptide.

Use Of Specific T2R Receptors To Identify Compounds That Block Bitter Taste

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US Patent:
7776561, Aug 17, 2010
Filed:
Mar 4, 2008
Appl. No.:
12/041956
Inventors:
Alexey Pronin - San Diego CA, US
Judy Connor - Vista CA, US
Huixian Tang - San Diego CA, US
Walter Keung - San Diego CA, US
Guy Servant - San Diego CA, US
Jon Elliot Adler - San Diego CA, US
Shawn O'Connell - San Diego CA, US
Paul Brust - San Diego CA, US
Assignee:
Senomyx, Inc. - San Diego CA
International Classification:
G01N 33/567
C07K 14/705
US Classification:
435 721, 435 71, 435 72, 436501
Abstract:
Assays for identifying compounds that modulate, preferably inhibit bitter taste associated with the activation of hT2R4, hT2R44 and/or hT2R61 are provided. The compounds identified according to these assays should modulate, e. g. , inhibit bitter taste associated with bitter tasting compounds including quinine, 6-nitrosaccharin, saccharin and/or denatonium. These compounds are useful additives for foods, beverages or medicinal preparationshaving a bitter taste.

Identification Of Bitter Ligands That Specifically Activate Human T2R Receptors And Related Assays For Identifying Human Bitter Taste Modulators

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US Patent:
7883856, Feb 8, 2011
Filed:
Jun 22, 2007
Appl. No.:
11/766974
Inventors:
Xiaodong Li - San Diego CA, US
Hong Xu - San Diego CA, US
Qing Li - San Diego CA, US
Huixian Tang - San Diego CA, US
Alexey Pronin - San Diego CA, US
Assignee:
Senomyx Inc. - San Diego CA
International Classification:
G01N 33/566
C07K 14/705
US Classification:
435 71, 435 72, 435 721, 436501
Abstract:
The present invention relates to the discovery that specific human taste receptors in the T2R taste receptor family respond to particular bitter compounds. Also, the invention relates to the discovery of specific hT2R9 alleles and their disparate activity in functional assays with the same biter ligands. The invention further relates to the use of these T2R receptors in assays for identifying ligands that modulate the activation of these taste receptors by specific bitter ligands and related compounds. These compounds may be used as additives and/or removed from foods, beverages, cosmetics and medicinals in order to modify (block) T2R-associated bitter taste. Also T2R ligands may be used as therapeutics to treat and modulate T2R associated gastrointestinal and metabolic functions as well as treat gastrointestinal and metabolic diseases such as eating disorders, food sensing, food absorption, obesity, diabetes, Crohn's disease, celiac disease, et al.

Human T2R Receptors For Ranitidine, Strychnine And Denatonium And Related Assays For Identifying Human Bitter Taste Modulators

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US Patent:
7915003, Mar 29, 2011
Filed:
Jul 2, 2008
Appl. No.:
12/166980
Inventors:
Xiaodong Li - Oceanside CA, US
Hong Xu - San Diego CA, US
Huixian Tang - San Diego CA, US
Qing Li - San Diego CA, US
Assignee:
Senomyx, Inc. - San Diego CA
International Classification:
G01N 33/566
C07K 14/705
US Classification:
435 72, 435 71, 435 721, 436501
Abstract:
The present invention relates to the discovery that specific human taste receptors in the T2R taste receptor family respond to particular bitter ligands, i. e. , acetaminophen, ranitidine, strychnine and denatonium. The present invention further relates to the use of these receptors in assays for identifying ligands that modulate the activation of these taste receptors and which may be used as additives in foods, beverages and medicinals for modifying (blocking) T2R-associated bitter taste.

Assays Which Screen For Compounds That Modulate Bitter Taste Of Chlorogenic Lactone Compounds

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US Patent:
7939276, May 10, 2011
Filed:
Jun 20, 2006
Appl. No.:
11/455693
Inventors:
Xiaodong Li - San Diego CA, US
Hong Xu - San Diego CA, US
Qing Li - Draper UT, US
Huixian Tang - San Diego CA, US
Assignee:
Senomyx, Inc. - San Diego CA
International Classification:
G01N 33/567
C07K 14/705
US Classification:
435 721, 530350, 738657, 514974
Abstract:
The present invention relates to the discovery that specific human taste receptors in the T2R taste receptor family respond to particular bitter compounds, i. e. , chlorogenic lactone compounds that contribute at least partially to the bitter taste of many coffee beverages. The present invention further relates to the use of these receptors in assays for identifying ligands that modulate the activation of these taste receptors by chlorogenic lactones and related compounds and which may be used as additives and/or removed from foods, beverages and medicinals in order to modify (block) T2R-associated bitter taste. A preferred embodiment is the use of the identified compounds as additives in coffee and coffee-flavored foods, beverages and medicinals.

Identification Of Bitter Ligands That Specifically Activate Human T2R Receptors And Related Assays For Identifying Human Bitter Taste Modulators

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US Patent:
8030008, Oct 4, 2011
Filed:
Nov 1, 2006
Appl. No.:
11/555617
Inventors:
Xiaodong Li - San Diego CA, US
Hong Xu - San Diego CA, US
Qing Li - San Diego CA, US
Huixian Tang - San Diego CA, US
Alexey Pronin - San Diego CA, US
Assignee:
Senomyx, Inc. - San Diego CA
International Classification:
G01N 33/567
C07K 14/705
US Classification:
435 72, 435 721, 436501
Abstract:
The present invention relates to the discovery that specific human taste receptors in the T2R taste receptor family respond to particular bitter compounds. The invention further relates to the use of these receptors in assays for identifying ligands that modulate the activation of these taste receptors by these bitter ligands and related compounds and which may be used as additives and/or removed from foods, beverages, cosmetics and medicinals in order to modify (block) T2R-associated bitter taste.

Use Of Specific T2R Taste Receptors To Identify Compounds That Block Bitter Taste

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US Patent:
8071320, Dec 6, 2011
Filed:
Aug 11, 2010
Appl. No.:
12/854570
Inventors:
Alexey Pronin - San Diego CA, US
Judy Connor - Vista CA, US
Huixian Tang - San Diego CA, US
Walter Keung - San Diego CA, US
Guy Servant - San Diego CA, US
Jon Elliot Adler - San Diego CA, US
Shawn O'Connell - San Diego CA, US
Paul Brust - San Diego CA, US
Assignee:
Senomyx, Inc. - San Diego CA
International Classification:
G01N 33/566
C07K 14/705
US Classification:
435 721, 435 71, 435 72, 436501
Abstract:
Assays for identifying compounds that modulate, preferably inhibit bitter taste associated with the activation of hT2R4, hT2R44 and/or hT2R61 are provided. The compounds identified according to these assays should modulate, e. g. , inhibit bitter taste associated with bitter tasting compounds including quinine, 6-nitrosaccharin, saccharin and/or denatonium. These compounds are useful additives for foods, beverages or medicinal preparations having a bitter taste.
Control profile
Huixian Tang from San Diego, CA, age ~62 Get Report