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Heinz G Floss

from Bellevue, WA
Age ~90

Heinz Floss Phones & Addresses

  • 5609 145Th Ave, Bellevue, WA 98006 (425) 562-1531
  • 233 Bangsberg Rd, Pt Charlotte, FL 33952 (941) 629-4223 (941) 629-9553
  • Port Charlotte, FL
  • Miami, FL
  • Saint Louis, MO
  • Grafton, MA
  • Columbus, OH

Publications

Us Patents

Maytansinoid Analogs As Antitumor Agents

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US Patent:
7838519, Nov 23, 2010
Filed:
Apr 4, 2005
Appl. No.:
10/599930
Inventors:
John M. Cassady - Corvallis OR, US
Heinz G. Floss - Bellevue WA, US
Assignee:
The Ohio State University Research Foundation - Columbus OH
International Classification:
C07D 498/18
A61K 31/55
A61P 35/00
US Classification:
5142295, 5142298, 540456
Abstract:
Ansamycin analogs, including maytansinoid analogs, and their use in treating cell proliferative diseases and conditions, and in particular, for use as antitumor agents.

Biosynthetic Gene Cluster For The Maytansinoid Antitumor Agent Ansamitocin

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US Patent:
20060084141, Apr 20, 2006
Filed:
Nov 21, 2002
Appl. No.:
10/496351
Inventors:
Heinz Floss - Bellevue WA, US
Eckhard Leistner - Meckenheim, DE
International Classification:
C12P 17/18
C07H 21/04
C12P 21/06
C12N 9/10
C12N 1/21
C12N 15/74
US Classification:
435069100, 536023200, 435193000, 435320100, 435252350, 435119000, 540462000
Abstract:
The present invention relates to compositions and methods involving antitumor agents derived from bacteria. In particular, the present invention provides the ansamitocin biosynthetic gene cluster for the production of novel maytansinoid analogs with potent antitumor activity and reduced human toxicity.

Valiolone, A Method Of Preparing It, And Its Use To Prepare Acarbose And Voglibose

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US Patent:
61505684, Nov 21, 2000
Filed:
Mar 30, 1999
Appl. No.:
9/280454
Inventors:
Heinz G. Floss - Bellevue WA
Sungsook Lee - Seattle WA
Ingo Tornus - Hennigsdorf, DE
Assignee:
University of Washington - Seattle WA
International Classification:
C07C 3514
C07C 3516
US Classification:
568833
Abstract:
Disclosed is the compound valiolone, which has the formula (I): ##STR1## a method of preparing valiolone, and a method of using valiolone to prepare acarbose and voglibose.
Heinz G Floss from Bellevue, WA, age ~90 Get Report