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Eric Feyfant

from Leominster, MA
Age ~54
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Also known as:
Isabelle Feyfant
Phone and address:
41 Olde Tavern Rd, Leominster, MA 01453
(781) 274-0861
Related to:
Isabelle C Feyfant, 62Alexandre Feyfant, 26
Connected to:
Boris N Feygelson, 66Miriam L Feygenson, 36Anna Feygin, 65Eugene Feygin, 50Yana Feygin, 40Austin D Feyh, 34Jerry G Feyh, 61Michael Feyh, 56Elmo Feyisa, 54Jill Feyka, 58

Eric Feyfant Phones & Addresses

  • 41 Olde Tavern Rd, Leominster, MA 01453 (781) 274-0861
  • 41 Kendall Rd, Lexington, MA 02421 (781) 274-0861
  • Lincoln, MA
  • Arlington, MA
  • New York, NY
  • 41 Kendall Rd, Lexington, MA 02421

Work

Company: Schrödinger Aug 1, 2013 Position: Director, biologics business development and applications

Education

Degree: Doctorates, Doctor of Philosophy School / High School: Aix - Marseille University 1996 to 2000 Specialities: Biophysics, Chemistry

Skills

Drug Discovery • Drug Design • Protein Chemistry • Molecular Modeling • Biochemistry • Biotechnology • Computational Chemistry • Organic Chemistry • Cheminformatics • Protein Engineering • Antibodies • Lead Change • Drug Development • Medicinal Chemistry • Pharmaceutical Industry • Structural Biology • Peptides • Chemistry • Oncology • Biophysics • Small Molecules • Bioinformatics • Organic Synthesis • Neuroscience • Cro • Purification • Biomarkers • Lc Ms • Adme • Docking • Inflammation • In Vitro • Biomarker Discovery • Cro Management • Lead Optimization • High Throughput Screening • Monoclonal Antibodies • Infectious Diseases • Gpcrs • Pharmacology • Pharmaceuticals

Languages

English • French

Interests

Cooking • Exercise • Investing • Traveling • Cruises • Outdoors • Home Improvement • Electronics • Reading • Crafts • Music • Sports • Camping • Travel • Movies • Collecting • Home Decoration

Emails

i***[email protected]

Industries

Biotechnology

Public records

Vehicle Records

Eric Feyfant

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Address:
41 Kendall Rd, Lexington, MA 02421
Phone:
(781) 274-0861
VIN:
5FNRL384X7B098053
Make:
HONDA
Model:
ODYSSEY
Year:
2007

Resumes

Resumes

Eric Feyfant Photo 1

Director, Biologics Business Development And Applications

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Location:
5 Dane Rd, Lexington, MA 02421
Industry:
Biotechnology
Work:
Schrödinger
Director, Biologics Business Development and Applications
Aileron Therapeutics Jan 2013 - Jul 2013
Senior Principal Scientist
Aileron Therapeutics Jan 2012 - Jan 2013
Principal Scientist
Pfizer Nov 2001 - Oct 2009
Principal Research Scientist
Rockefeller University 2001 - 2001
Postdoctoral Fellow
Education:
Aix - Marseille University 1996 - 2000
Doctorates, Doctor of Philosophy, Biophysics, Chemistry The Rockefeller University 1996 - 2000
Doctorates, Doctor of Philosophy, Biophysics, Chemistry Aix - Marseille University 1992 - 1996
Master of Science, Masters, Biochemistry Lycée Du Sacré Coeur 1988
Skills:
Drug Discovery
Drug Design
Protein Chemistry
Molecular Modeling
Biochemistry
Biotechnology
Computational Chemistry
Organic Chemistry
Cheminformatics
Protein Engineering
Antibodies
Lead Change
Drug Development
Medicinal Chemistry
Pharmaceutical Industry
Structural Biology
Peptides
Chemistry
Oncology
Biophysics
Small Molecules
Bioinformatics
Organic Synthesis
Neuroscience
Cro
Purification
Biomarkers
Lc Ms
Adme
Docking
Inflammation
In Vitro
Biomarker Discovery
Cro Management
Lead Optimization
High Throughput Screening
Monoclonal Antibodies
Infectious Diseases
Gpcrs
Pharmacology
Pharmaceuticals
Interests:
Cooking
Exercise
Investing
Traveling
Cruises
Outdoors
Home Improvement
Electronics
Reading
Crafts
Music
Sports
Camping
Travel
Movies
Collecting
Home Decoration
Languages:
English
French

Publications

Us Patents

Antibodies Against Human Interleukin-13 And Pharmaceutical Compositions Thereof

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US Patent:
7615213, Nov 10, 2009
Filed:
Jun 9, 2005
Appl. No.:
11/149309
Inventors:
Marion T. Kasaian - Charlestown MA, US
Lioudmila Tchistiakova - Andover MA, US
Geertruida M. Veldman - Sudbury MA, US
Kimberly Ann Marquette - Somerville MA, US
Xiang-Yang Tan - Reading MA, US
Debra D. Donaldson - Medford MA, US
Laura Long Lin - Weston MA, US
Tania Shane - Newton MA, US
Amy Sze Pui Tam - Medford MA, US
Eric Feyfant - Lexington MA, US
Nancy L. Wood - Somerville MA, US
Lori J. Fitz - Somerville MA, US
Angela M. Widom - Acton MA, US
Kevin D. Parris - Auburndale MA, US
Samuel J. Goldman - Acton MA, US
Jose W. Saldanha - Middlesex, GB
Assignee:
Wyeth - Madison NJ
International Classification:
A61K 39/395
US Classification:
4241331, 4241451, 5303873, 53038823
Abstract:
This application relates to antibodies, e. g. , humanized antibodies, and antigen-binding fragments thereof, that bind to interleukin-13 (IL-13), in particular, human IL-13, and their uses in regulating immune responses mediated by IL-13. The antibodies disclosed herein are useful in diagnosing, preventing, and/or treating a subject, e. g. , a human patient, one or more IL-13-associated disorders, e. g. , respiratory disorders (e. g. , asthma); atopic disorders (e. g. , allergic rhinitis); inflammatory and/or autoimmune conditions of the skin (e. g. , atopic dermatitis), and gastrointestinal organs (e. g. , inflammatory bowel diseases (IBD)), as well as fibrotic and cancerous disorders.

Glutamate Aggrecanase Inhibitors

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US Patent:
7998965, Aug 16, 2011
Filed:
May 14, 2009
Appl. No.:
12/465840
Inventors:
Jerauld Stanley Skotnicki - Westfield NJ, US
Steve Yik-Kai Tam - Wellesley MA, US
Tarek Suhayl Mansour - New City NY, US
David Brian How - Nyack NY, US
Joshua James Sabatini - White Plains NY, US
Jason Shaoyun Xiang - Winchester MA, US
Eric Feyfant - Lexington MA, US
Assignee:
Wyeth LLC - Madison NJ
International Classification:
A61K 31/4965
A61K 31/16
A61K 31/34
A61K 31/44
A61K 31/38
C07C 237/00
C07D 307/87
C07D 333/02
C07D 241/02
US Classification:
51425506, 514616, 514469, 514355, 514438, 564153, 549462, 549 29, 544336
Abstract:
The present invention relates to modulators of metalloproteinase activity.

Antibodies Against Human Interleukin-13 And Uses Therefor

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US Patent:
8221752, Jul 17, 2012
Filed:
Oct 8, 2009
Appl. No.:
12/575896
Inventors:
Marion T. Kasaian - Cambridge MA, US
Lioudmila Gennadievna Tchistiakova - Andover MA, US
Geertruida Machteld Veldman - Sudbury MA, US
Kimberly Ann Marquette - Somerville MA, US
Xiang-Yang Tan - Reading MA, US
Debra D. Donaldson - Medford MA, US
Laura Long Lin - Weston MA, US
Tania Shane - Newton MA, US
Amy Sze Pui Tam - Medford MA, US
Eric Feyfant - Lexington MA, US
Nancy L. Wood - Somerville MA, US
Lori J. Fitz - Somerville MA, US
Angela M. Widom - Acton MA, US
Kevin D. Parris - Auburndale MA, US
Samuel J. Goldman - Acton MA, US
Jose W. Saldanha - Enfield, GB
Assignee:
Wyeth LLC - Madison NJ
International Classification:
A61K 39/395
US Classification:
4241331, 4241581
Abstract:
This application relates to antibodies, e. g. , humanized antibodies, and antigen-binding fragments thereof, that bind to interleukin-13 (IL-13), in particular, human IL-13, and their uses in regulating immune responses mediated by IL-13. The antibodies disclosed herein are useful in diagnosing, preventing, and/or treating a subject, e. g. , a human patient, one or more IL-13-associated disorders, e. g. , respiratory disorders (e. g. , asthma); atopic disorders (e. g. , allergic rhinitis); inflammatory and/or autoimmune conditions of the skin (e. g. , atopic dermatitis), and gastrointestinal organs (e. g. , inflammatory bowel diseases (IBD)), as well as fibrotic and cancerous disorders.

Glutamate Aggrecanase Inhibitors

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US Patent:
20070043066, Feb 22, 2007
Filed:
Jul 11, 2006
Appl. No.:
11/484005
Inventors:
David How - Nyack NY, US
Joshua Sabatini - White Plains NY, US
Jason Xiang - Winchester MA, US
Manus Ipek - Watertown MA, US
Eric Feyfant - Lexington MA, US
Assignee:
Wyeth - Madison NJ
International Classification:
A61K 31/505
A61K 31/44
A61K 31/381
A61K 31/34
A61K 31/198
A61K 31/165
US Classification:
514275000, 514447000, 514471000, 514563000, 514616000, 514464000, 514357000, 544330000, 549076000, 562450000, 564152000, 546315000, 549493000
Abstract:
The present invention relates to modulators of metalloproteinase activity.

Peptidomimetic Macrocycles

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US Patent:
20130274205, Oct 17, 2013
Filed:
Feb 14, 2013
Appl. No.:
13/767852
Inventors:
Carl Elkin - Arlington MA, US
Huw M. Nash - Lexington MA, US
Tomi K. Sawyer - Southborough MA, US
Bradford J. Graves - Nutley NJ, US
Eric Feyfant - Lexington MA, US
International Classification:
C07K 7/54
US Classification:
514 211, 530317
Abstract:
Provided herein are peptidomimetic macrocycles and methods of using such macrocycles for the treatment of disease.

Mutant Rsv F Protein And Use Thereof

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US Patent:
20230086093, Mar 23, 2023
Filed:
Dec 23, 2020
Appl. No.:
17/788717
Inventors:
- Osaka-shi, JP
Hiroyuki KISHIDA - Osaka-shi, JP
Kei TAKEDOMI - Osaka-shi, JP
Davide BRANDUARDI - New York NY, US
Eliud OLOO - New York NY, US
Eric FEYFANT - New York NY, US
Osamu ICHIHARA - Chiyoda-ku, JP
Assignee:
MITSUBISHI TANABE PHARMA CORPORATION - Osaka-shi
International Classification:
C07K 14/005
A61P 31/14
A61K 39/155
Abstract:
The present invention provides a mutant RSV F protein having a mutation, wherein the mutation is a substitution of a leucine corresponding to a leucine at position of an amino acid sequence of SEQ ID NO: 1 or a leucine corresponding to a leucine at position with a cysteine, and a substitution of a leucine corresponding to a leucine at position with a cysteine, and a disulfide bond is formed between the cysteines. Further provided is a mutant RSV F protein having a mutation, wherein the mutation is a substitution of a glutamic acid corresponding to a glutamic acid at position of the amino acid sequence of SEQ ID NO: 1 with a non-acidic amino acid.

Peptidomimetic Macrocycles

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US Patent:
20190343914, Nov 14, 2019
Filed:
Dec 18, 2018
Appl. No.:
16/223473
Inventors:
- Watertown MA, US
Carl ELKIN - Arlington MA, US
Huw M. NASH - Lexington MA, US
Tomi K. SAWYER - Southborough MA, US
Bradford J. GRAVES - Nutley NJ, US
Eric FEYFANT - Lexington MA, US
International Classification:
A61K 38/10
C07K 14/47
C07K 1/113
A61K 45/06
C07K 7/54
C07K 7/08
C07K 7/06
A61K 38/03
A61K 38/08
Abstract:
Provided herein are peptidomimetic macrocycles containing amino acid sequences with at least two modified amino acids that form an intramolecular cross-link that can help to stabilize a secondary structure of the amino acid sequence. Suitable sequences for stabilization include those with homology to the p53 protein. These sequences can bind to the MDM2 and/or MDMX proteins. Also provided herein are methods of using such macrocycles for the treatment of diseases and disorders, such as cancers or other disorders characterized by a low level or low activity of a p53 protein or high level of activity of a MDM2 and/or MDMX protein.

Peptidomimetic Macrocycles And Use Thereof In Regulating Hif1Alpha

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US Patent:
20190225650, Jul 25, 2019
Filed:
Jan 30, 2019
Appl. No.:
16/262121
Inventors:
- Watertown MA, US
Noriyuki KAWAHATA - West Roxbury MA, US
Huw M. NASH - Lexington MA, US
Carl ELKIN - Arlington MA, US
Eric FEYFANT - Lexington MA, US
International Classification:
C07K 7/56
A61K 47/54
Abstract:
The present invention provides peptidomimetic macrocycles capable of regulating HIF1α and methods of using such macrocycles for the treatment of diseases.
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Eric Feyfant from Leominster, MA, age ~54 Get Report