Inventors:
Adnan M. M. Mjalli - Oak Ridge NC, US
Christopher Behme - Jamestown NC, US
Daniel P. Christen - Jamestown NC, US
Devi Reddy Gohimukkula - Jamestown NC, US
Dharma Rao Polisetti - High Point NC, US
James Quada - High Point NC, US
Jennifer L. R. Freeman - Winston-Salem NC, US
Kalpathy Santhosh - Jamestown NC, US
Muralidhar Bondlela - Greensboro NC, US
Mustafa Guzel - Jamestown NC, US
Ravindra Reddy Yarragunta - Greensboro NC, US
Robert Carl Andrews - Jamestown PA, US
Stephen Thomas Davis - Durham NC, US
Thomas Scott Yokum - Greensboro NC, US
Assignee:
TransTech Pharma, Inc. - High Point NC
International Classification:
C07D 491/056
A61K 31/436
Abstract:
The present invention is directed to substituted azoanthracene derivatives or pharmaceutically acceptable salts thereof that modulate the human GLP-1 receptor and that may be useful in the treatment of diseases, disorders, or conditions in which modulation of the human GLP-1 receptor is beneficial, such as diabetes mellitus type 2. The invention is also directed to pharmaceutical compositions comprising these compounds and to the use of these compounds and compositions in the treatment of such diseases, disorders, or conditions in which modulation of the human GLP-1 receptor is beneficial.