Bryan C Grygus

20100124676, May 20, 2010

Nov 20, 2008

12/274446

John E. Meschter - New York NY, US
James K. Prueitt - Ballston Lake NY, US
Paul Bishop - Gansevoort NY, US
Robert Miller - Delmar NY, US
Karen Thatcher - East Berne NY, US
Bryan Grygus - Clifton Park NY, US
Michael Chen - Cambridge MA, US
Zhigang Qi - Schenectady NY, US

B01D 19/00
H01M 8/04

429 12, 95260, 95254, 96220

A system and method for managing gas bubbles in a liquid flow system are described. In particular, according to the system and method, novel techniques reduce a volume of cavities in the liquid flow system and limit a cross-sectional area of the liquid flow system to a maximum cross-sectional area of tolerably sized bubbles. In this manner, by reducing the cavity volumes and limiting cross-sectional areas, the formation of intolerably sized bubbles and the aggregation of tolerably sized bubbles into intolerably sized bubbles are each substantially prevented. Also, bubbles may be removed from the system to reduce the quantity of bubbles that are to be managed.

20100124678, May 20, 2010

Nov 20, 2008

12/274567

John Meschter - New York NY, US
Bryan Grygus - Troy NY, US
Nagaraja K. Yaddanapudi - Tarrytown NY, US
Keith Brown - Clifton Park NY, US
James Prueitt - Ballston Lake NY, US
Karen Thatcher - East Berne NY, US
Michael Chen - Cambridge MA, US
George Allen - Middle Grove NY, US
Wenpeng Liu - Niskayuna NY, US
Zhigang Qi - Schenectady NY, US
Garrick D.S. Smith - Madison WI, US

MTI MICROFUEL CELLS, INC. - Albany NY

H01M 8/04
H01M 8/00

429 13, 429 25, 429 24

Fuel feed systems capable of providing substantially consistent flow of fuel to a fuel cell and also capable of tolerating varying pressures from a reservoir (also referred to as fuel supply or fuel cell cartridge) and the fuel cell while maintaining substantially consistent control flow to the fuel cell are disclosed.

20100124689, May 20, 2010

Nov 20, 2008

12/274515

John Meschter - New York NY, US
Bryan Grygus - Troy NY, US
Nagaraja K. Yaddanapudi - Tarrytown NY, US
Keith Brown - Clifton Park NY, US
James Prueitt - Ballston Lake NY, US
Karen Thatcher - East Berne NY, US
Michael Chen - Cambridge MA, US
George Allen - Middle Grove NY, US
Wenpeng Liu - Niskayuna NY, US
Zhigang Qi - Schenectady NY, US
Garrick D. S. Smith - Madison WI, US

MTI MICROFUEL CELLS, INC. - Albany NY

H01M 2/14
B23P 21/00

429 38, 29469

A system-to-reservoir connector is disclosed in which a system-side-sub-connector and a reservoir-side-sub-connector provide for a fluid connection that is resilient to external forces, is substantially leak-proof upon insertion and retraction, and is orientation independent.

20100122733, May 20, 2010

Nov 20, 2008

12/274478

Bryan Grygus - Troy NY, US
Keith Brown - Clifton Park NY, US

MTI MicroFuel Cells, Inc. - Albany NY

F17D 1/08
F16K 7/00
F15C 3/00

137 14, 251331, 13756501

Embodiments of a valve are disclosed that allow for the control and adjustment of a fluid flow between a valve inlet port and a valve output port as a function of the pressure at the valve inlet port, a pressure at a first pressure input port, and a reference pressure.

20220370721, Nov 24, 2022

Aug 1, 2022

17/816615

- Tarrytown NY, US
Justin BECHSTEIN - Philadelphia PA, US
Jeremy ODEGARD - Hudson WI, US
Sibgat ULLA - Rensselaer NY, US
Daniel HALBIG - Rensselaer NY, US
Bryan GRYGUS - Clifton Park NY, US
Prithvi SINGH - Rensselaer NY, US
Andrew DUMONT - Rensselaer NY, US
David NETT - Rensselaer NY, US
Tasha GILLUM - Rensselaer NY, US
Ryan AINSWORTH - Rensselaer NY, US

Regeneron Pharmaceuticals, Inc. - Tarrytown NY

A61M 5/315
A61M 5/31

Disclosed herein are devices and methods for delivering a predetermined volume of a drug substance or other product including a fluid. An exemplary device may include a body configured to receive a drug substance therein, and a plunger rod disposed at least partially inside the body to distally move a stopper in the body. The device may include a component configured to regulate distal movement of the plunger rod in a priming step and in a subsequent delivery step, so that the device may be accurately primed and may accurately dispense a predetermined volume of a drug substance.

20220355040, Nov 10, 2022

Jul 25, 2022

17/872959

- Tarrytown NY, US
Danielle LAIACONA - Rexford NY, US
Ross KENYON - Saratoga Springs NY, US
Trevor LANGLEY - Rensselaer NY, US
Bryan GRYGUS - Clifton Park NY, US
Eric HOUDE - Queensbury NY, US
Jeremy McNAMARA - Albany NY, US
Kathryn VENUTO - Waltham MA, US

Regeneron Pharmaceuticals, Inc. - Tarrytown NY

A61M 5/315

Disclosed herein are delivery devices for delivering a volume of a drug product, placebo product, or other product including a fluid. The devices may include a barrel having a longitudinal axis, a proximal end region, and a distal end region. The proximal end region may include an opening, and the barrel may be configured to receive a drug therein. A plunger rod may be disposed at least partially inside the barrel and protruding from the opening. The plunger rod may include a rack having a plurality of teeth. The device may further include a pinion having a plurality of teeth configured to engage with the plurality of teeth of the rack, and rotation of the pinion against the rack may move at least a part of the plunger rod along the longitudinal axis of the barrel.

20220203032, Jun 30, 2022

Dec 29, 2021

17/565237

- Tarrytown NY, US
Bryan GRYGUS - Clifton Park NY, US
Trevor LANGLEY - Rensselaer NY, US
Andrew DUMONT - Rensselaer NY, US
Bart E. BURGESS - Bernville PA, US
Matthew PAUSLEY - Gansevoort NY, US
Ross KENYON - Saratoga Springs NY, US

Regeneron Pharmaceuticals, Inc. - Tarrytown NY

A61M 5/20

An auto-injector may include a container capable of comprising a medicament; a shuttle coupled to the container and on a horizontal path with a first state and a second state; an energy source configured to release energy to translate the container and to translate the shuttle, preferably the energy source is pressurized fluid from a can; an impediment preventing horizontal movement of the shuttle before activation of the auto-injector; and a needle having a first end configured to extend out of the auto-injector, and a second end configured to extend into the container, wherein the second end of the needle and the container are not in fluid communication with one another before activation of the auto-injector.

20220193343, Jun 23, 2022

Dec 29, 2021

17/565104

- Tarrytown NY, US
Bryan GRYGUS - Clifton Park NY, US
Daniel HALBIG - Ballston Lake NY, US
Ross KENYON - Saratoga Springs NY, US
Trevor LANGLEY - Rensselaer NY, US
Jeremy MCNAMARA - Albany NY, US
Matthew PAUSLEY - Gansevoort NY, US
Andrew DUMONT - Rensselaer NY, US
Paige WAECHTER - Cohoes NY, US
John BURKE - Ickleton, GB
Martin BONTOFT - Ickleton, GB
Craig MCGARRELL - Whitburn, GB
Scott MARTIN - Edinburgh, GB
James Nicholas MOWER - Edinburgh, GB
James Cunningham GLENCROSS - Edinburgh, GB
James Donald MCLUSKY - Edinburgh, GB
Andrew LABAT-ROCHECOUSTE - Keynsham, GB
Tim QUIGG - Ashley Down, GB
Matt HILL - Llanishen, GB
Matthew PHILLIPPO - Bath, GB
Kirsty WYNNE - Sheffield, GB

Regeneron Pharmaceuticals, Inc. - Tarrytown NY

A61M 5/20
A61M 5/24
A61M 5/315

An auto-injector may include a housing having a longitudinal axis and a transverse axis, the housing having a shorter dimension along the transverse axis than along the longitudinal axis, wherein the transverse axis is perpendicular to the longitudinal axis; a flowpath having a first end and a second end; and a container enclosing a first fluid, the container extending from a first end toward a second end along or parallel to the longitudinal axis and being movable from a first position to a second position along or parallel to the longitudinal axis, the container being fluidly isolated from the flowpath in the first position and fluidly connected to the flowpath in the second position.