Inventors:
Paul Ala - Newark DE, US
Jacob Clement - N.Vancouver, CA
Andrew Magee - Maynard MA, US
Scott Moe - Marlborough MA, US
Manuel Navia - Lexington MA, US
Aloka Roy - Acton MA, US
International Classification:
A61K031/541
A61K031/5377
A61K031/496
A61K031/451
A61K031/429
A61K031/4245
A61K031/4178
C07D417/02
C07D413/02
C 07D 4 5/02
US Classification:
514/227800, 514/235800, 514/254070, 514/254030, 514/326000, 514/363000, 514/364000, 514/383000, 514/397000, 514/406000, 544/060000, 544/136000, 544/137000, 544/366000, 544/370000, 544/371000, 546/210000, 546/208000, 548/136000, 548/143000, 548/266200, 548/315400, 548/365700
Abstract:
The invention relates to nitrofuran-containing compounds, compositions comprising the compounds, and methods of using the compounds and compound compositions. The compounds and compositions comprising them are useful for treating disease or disease symptoms. The invention also provides for methods of making the compounds, and methods for identifying compounds with desired biological activity.