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Zhiguang X Yu

from Libertyville, IL
Age ~60

Zhiguang Yu Phones & Addresses

  • Libertyville, IL
  • Irvine, CA
  • Columbus, OH
  • Piscataway, NJ
  • Kingston, UT
  • Vernon Hills, IL
  • Park City, IL

Publications

Us Patents

Pigf-1 Assay And Kits And Components Thereof

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US Patent:
20100015637, Jan 21, 2010
Filed:
Jun 16, 2009
Appl. No.:
12/485114
Inventors:
Susan E. Brophy - Lindenhurst IL, US
Lianli Chi - Waukegan IL, US
Saul A. Datwyler - Evanston IL, US
David J. Hawksworth - Lake Villa IL, US
Don M. Laird - Mundelein IL, US
Sharmila Manoj - Arlington Heights IL, US
Mary S. Pinkus - Chicago IL, US
Dominick L. Pucci - Libertyville IL, US
Carol S. Ramsay - Arlington Heights IL, US
David C. Sogin - Highland Park IL, US
Bailin Tu - Libertyville IL, US
Joan D. Tyner - Beach Park IL, US
Lowell J Tyner - Chicago IL, US
Zhiguang Yu - Libertyville IL, US
Robert N. Ziemann - Lindenhurst IL, US
Assignee:
ABBOTT LABORATORIES - Abbott Park IL
International Classification:
G01N 33/53
C07K 16/18
C12N 5/16
C12N 5/18
US Classification:
435 79, 5303871, 435326, 5303881, 436547, 435 71
Abstract:
The present disclosure relates to glycosylated and deglycosylated human PlGF-1, methods of using the glycosylated and deglycosylated human PlGF-1, antibodies that bind to human PlGF-1, methods of using the antibodies and human PlGF-1 immunoassays and kits.

Soluble Fms-Like Tyrosine Kinase-1 (Sflt-1) Antibody And Related Composition, Kit, Methods Of Using, And Materials And Method For Making

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US Patent:
20100266575, Oct 21, 2010
Filed:
Dec 21, 2009
Appl. No.:
12/643847
Inventors:
Susan E. Brophy - Lindenhurst IL, US
Saul A. Datwyler - Evanston IL, US
David J. Hawksworth - Lake Villa IL, US
Don C. Laird - Mundelein IL, US
Sharmila Manoj - Arlington Heights IL, US
Dominick L. Pucci - Libertyville IL, US
Bryan C. Tieman - Elmhurst IL, US
Joan Tyner - Beach Park IL, US
Lowell J. Tyner - Chicago IL, US
Zhiguang Yu - Libertyville IL, US
Assignee:
ABBOTT LABORATORIES - Abbott Park IL
International Classification:
A61K 39/395
C07K 16/40
G01N 33/573
C07H 21/04
C12N 15/63
C12N 5/10
C12P 21/00
A61P 9/12
US Classification:
4241301, 5303891, 435 74, 536 231, 4353201, 435325, 435 696
Abstract:
An isolated antibody that specifically binds to sFlt-1 or a fragment thereof having (i) a variable heavy domain region comprising the amino acid sequence of SEQ ID NO: 2, (ii) a variable light domain region comprising the amino acid sequence of SEQ ID NO: 4, or (iii) both (i) and (ii), a pharmaceutical composition and a kit comprising such an antibody, a method of making such an antibody, a method of determining the presence, amount or concentration of sFlt-1 or a fragment thereof in a test sample, a method of treating a patient in therapeutic or prophylactic need of an antagonist of sFlt-1, an isolated nucleic acid comprising a nucleotide sequence encoding the amino acid sequence of (i) SEQ ID NO: 2, (ii) SEQ ID NO: 4, or (iii) both (i) and (ii), optionally as part of a vector, and a host cell comprising and expressing such a nucleic acid.

Soluble Fms-Like Tyrosine Kinase-1 (Sflt-1) Antibody And Related Composition, Kit, Methods Of Using, And Materials And Method For Making

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US Patent:
20130040407, Feb 14, 2013
Filed:
Oct 15, 2012
Appl. No.:
13/652402
Inventors:
Abbott Laboratories - , US
Saul A. Datwyler - Evanston IL, US
David J. Hawksworth - Lake Villa IL, US
Don C. Laird - Mundelein IL, US
Sharmila Manoj - Arlington Heights IL, US
Dominick L. Pucci - Libertyville IL, US
Bryan C. Tieman - Elmhurst IL, US
Joan D. Tyner - Beach Park IL, US
Zhiguang Yu - Libertyville IL, US
International Classification:
G01N 33/577
G01N 33/566
US Classification:
436501
Abstract:
An isolated antibody that specifically binds to sFlt-1 or a fragment thereof having (i) a variable heavy domain region comprising the amino acid sequence of SEQ ID NO: 2, (ii) a variable light domain region comprising the amino acid sequence of SEQ ID NO: 4, or (iii) both (i) and (ii), a pharmaceutical composition and a kit comprising such an antibody, a method of making such an antibody, a method of determining the presence, amount or concentration of sFlt-1 or a fragment thereof in a test sample, a method of treating a patient in therapeutic or prophylactic need of an antagonist of sFlt-1, an isolated nucleic acid comprising a nucleotide sequence encoding the amino acid sequence of (i) SEQ ID NO: 2, (ii) SEQ ID NO: 4, or (iii) both (i) and (ii), optionally as part of a vector, and a host cell comprising and expressing such a nucleic acid.
Zhiguang X Yu from Libertyville, IL, age ~60 Get Report