US Patent:
20040122045, Jun 24, 2004
Inventors:
Zhelong Xu - Chapel Hill NC, US
James Downey - Mobile AL, US
Assignee:
Aventis Pharmaceuticals Inc. - Bridgewater NJ
International Classification:
A61K031/4745
Abstract:
This invention is directed to methods of providing cardioprotection in a patient in need thereof comprising administering to said patient a pharmaceutically effective amount of a compound having adenosine A1/A2 agonistic activity, or a pharmaceutically acceptable salt thereof, or a pharmaceutical composition thereof, beginning at a time less than 10 minutes after the onset reperfusion, at reperfusion, and ten minutes or more before reperfusion, and continuing for a period of more than 30 minutes following the onset of reperfusion.