US Patent:
20140045819, Feb 13, 2014
Inventors:
Scott B. Hoyt - Hoboken NJ, US
Whitney Lane Petrilli - Jersey City NJ, US
Clare London - Chatham NJ, US
Yusheng Xiong - Plainsboro NJ, US
Jerry Andrew Taylor - Trenton NJ, US
Amjad Ali - Freehold NJ, US
Michael Man-Chu Lo - Edison NJ, US
Timothy J. Henderson - Edison NJ, US
Qingzhong Hu - Saarbrucken, DE
Rolf Hartmann - Saarbrucken, DE
Lina Yin - Saarbrucken, DE
Ralf Heim - Wiesbaden, DE
Emmanuel Bey - Forbach, DE
Rohit Saxena - Lucknow, IN
Swapan Kumar Samanta - Nandini Layout, IN
Bheemashankar A. Kulkarni - Rajajinagar, IN
Assignee:
ElexoPharm GmbH - Saarbrucken
SCHERING CORPORATION - Rahway NJ
International Classification:
C07D 487/04
C07D 471/04
US Classification:
51421021, 546 82, 514293, 540578, 51421402
Abstract:
This invention relates to tricyclic triazole analogues of the formula I or their pharmaceutically acceptable salts, wherein the variable are defined herein. The inventive compounds selectively inhibit aldosterone synthetase. This invention also provides for pharmaceutical compositions comprising the compounds of Formula I or their salts as well as to methods for the treatment, amelioration or prevention of conditions that could be treated by inhibiting aldosterone synthetase.