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Yuping A Cai

from Plainfield, IN
Age ~61

Yuping Cai Phones & Addresses

  • Plainfield, IN
  • Indianapolis, IN
  • Carmel, IN
  • Richmond, CA
  • 1126 9Th St, Berkeley, CA 94710 (510) 528-9839
  • Lansing, MI
  • East Lansing, MI

Resumes

Resumes

Yuping Cai Photo 1

Yuping Cai

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Location:
Indianapolis, IN
Industry:
Pharmaceuticals
Work:
Eli Lilly and Company
Senior Research Scinetist

Uc Berkeley 1993 - 1999
Post Docteral Scientist

Uc Berkeley 1993 - 1999
Senior Research Scinetist
Education:
University of California, Berkeley 1994 - 1999
Michigan State University 1986 - 1991
Doctorates, Doctor of Philosophy, Molecular Biology, Genetics
Skills:
Chromatography
Qpcr
Cell Biology
Elisa
Western Blotting
Hplc
Cgmp
Gmp
Data Analysis
Biotechnology
Pcr
Cell
Dna
Life Sciences
Cell Culture
Protein Engineering
Fermentation
Purification
Fluorescence
Drug Discovery
Molecular Biology
Biochemical Engineering
Pan
Bioinformatics
Process Development
Sds Page
Cell Based Assays
Microbiology
Rt Pcr
Protein Expression
Bioprocess Development
Product Development
Protein Purification
Genetics
Biochemistry
Technology Transfer
Flow Cytometry
R&D
Sop
Tissue Culture
Protein Chemistry
Biopharmaceuticals
Yuping Cai Photo 2

Yuping Cai

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Publications

Us Patents

Engineering Of Living Cells For The Expression Of Holo-Phycobiliprotein-Based Constructs

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US Patent:
6740507, May 25, 2004
Filed:
Jul 31, 2001
Appl. No.:
09/919486
Inventors:
Alexander N. Glazer - Berkeley CA
Aaron J. Tooley - Berkeley CA
Yuping Cai - Carmel IN
Assignee:
The Regents of the University of California - Oakland CA
International Classification:
C12P 2104
US Classification:
435 701, 435325, 4352523, 4352522, 435455, 435468, 435449, 435419, 435 792, 4353201, 435 6
Abstract:
Recombinant cells which express a fluorescent holo-phycobiliprotein fusion protein and methods of use are described. The cells comprises a bilin, a recombinant bilin reductase, an apo-phycobiliprotein fusion protein precursor of the fusion protein comprising a corresponding apo-phycobiliprotein domain, and a recombinant phycobiliprotein domain-bilin lyase, which components react to form the holo-phycobiliprotein fusion protein. Also described are holo-phycobiliprotein based transcription reporter cells and assays, which cells conditionally express a heterologous-to-the-cell, fluorescent, first holo-phycobiliprotein domain.

Multifunctional Recombinant Phycobiliprotein-Based Fluorescent Constructs And Phycobilisome Display

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US Patent:
7169582, Jan 30, 2007
Filed:
Jul 10, 2003
Appl. No.:
10/617208
Inventors:
Alexander N. Glazer - Berkeley CA, US
Yuping Cai - Indianapolis IN, US
Assignee:
Regents of the University of California - Oakland CA
International Classification:
C12N 15/09
C12N 1/20
C07K 14/00
US Classification:
435 697, 435 691, 4353201, 4352521, 435 77, 530350, 536 231, 436501
Abstract:
The invention provides multifunctional fusion constructs which are rapidly incorporated into a macromolecular structure such as a phycobilisome such that the fusion proteins are separated from one another and unable to self-associate. The invention provides methods and compositions for displaying a functional polypeptide domain on an oligomeric phycobiliprotein, including fusion proteins comprising a functional displayed domain and a functional phycobiliprotein domain incorporated in a functional oligomeric phycobiliprotein. The fusion proteins provide novel specific labeling reagents.

Multifunctional Recombinant Phycobiliprotein-Based Fluorescent Constructs And Phycobilisome Display

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US Patent:
7176000, Feb 13, 2007
Filed:
Jul 10, 2003
Appl. No.:
10/617012
Inventors:
Alexander N. Glazer - Berkeley CA, US
Yuping Cai - Indianapolis IN, US
Assignee:
Regents of the University of California - Oakland CA
International Classification:
C12N 15/09
C12N 1/20
C07K 14/00
US Classification:
435 697, 435 691, 4353201, 4352521, 435 77, 530350, 536 231, 436501
Abstract:
The invention provides multifunctional fusion constructs which are rapidly incorporated into a macromolecular structure such as a phycobilisome such that the fusion proteins are separated from one another and unable to self-associate. The invention provides methods and compositions for displaying a functional polypeptide domain on an oligomeric phycobiliprotein. including fusion proteins comprising a functional displayed domain and a functional phycobiliprotein domain incorporated in a functional oligomeric phycobiliprotein. The fusion proteins provide novel specific labeling reagents.

Anti-Hepcidin Antibodies And Uses Thereof

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US Patent:
20090136495, May 28, 2009
Filed:
Oct 29, 2008
Appl. No.:
12/260125
Inventors:
Dennis Patrick Gately - San Diego CA, US
Donmienne Doen Mun Leung - San Diego CA, US
Barbara Anne Swanson - Encinitas CA, US
Ying Tang - San Diego CA, US
YuPing Anthony Cai - Carmel IN, US
LuHong He - Carmel IN, US
Peng Luan - Fishers IN, US
Derrick Ryan Witcher - Fishers IN, US
International Classification:
A61K 39/395
C07K 16/18
C12N 15/11
C12P 21/04
G01N 33/53
C12N 15/00
C12N 5/06
US Classification:
4241331, 5303873, 536 2353, 4353201, 435358, 435 696, 435 72
Abstract:
Monoclonal antibodies are provided that selectively bind human hepcidin-25 and are characterized as having high affinity for human hepcidin-25 and strong human mature hepcidin neutralizing properties. The antibodies of the invention are useful therapeutically for increasing serum iron levels, reticulocyte count, red blood cell count, hemoglobin, and/or hematocrit in a human and for the treatment and diagnosis of mature hepcidin-promoted disorders such as anemia, in a human subject.

Multifunctional Recombinant Phycobiliprotein-Based Fluorescent Constructs And Phycobilisome Display

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US Patent:
6649376, Nov 18, 2003
Filed:
Dec 21, 1999
Appl. No.:
09/469194
Inventors:
Alexander N. Glazer - Berkeley CA
Yuping Cai - Indianapolis IN
Assignee:
The Regents of the University of California - Oakland CA
International Classification:
C12N 506
US Classification:
435 697, 435 77, 435 691, 4353201, 4352521, 435183, 435822, 530350, 536 231, 436501, 436519, 436536, 436 63
Abstract:
The invention provides multifunctional fusion constructs which are rapidly incorporated into a macromolecular structure such as a phycobilisome such that the fusion proteins are separated from one another and unable to self-associate. The invention provides methods and compositions for displaying a functional polypeptide domain on an oligomeric phycobiliprotein, including fusion proteins comprising a functional displayed domain and a functional phycobiliprotein domain incorporated in a functional oligomeric phycobiliprotein. The fusion proteins provide novel specific labeling reagents.
Yuping A Cai from Plainfield, IN, age ~61 Get Report