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Youzhi Tong

from Manhasset, NY
Age ~62
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Also known as:
Youzh Tong, Zhi Tong You, Tong Youzhi, I Tong
Phone and address:
6 Shoredale Dr, North Hills, NY 11030
(516) 627-1838
Related to:
Hong ZhangJae M You, 46Yan Z Zhao, 59Zhou Hang, 48Jiangang Zhang, 57Ying Zhang, 54
Connected to:
Alyssa T Tong, 37Andy Tong, 53Annabella Tong, 42Argus C Tong, 48Audrey Tong, 124Bernice C Tong, 65Billy K Tong, 60Bo L Tong, 69Camille M Tong, 46Carole A Tong, 82

Youzhi Tong Phones & Addresses

  • 6 Shoredale Dr, Manhasset, NY 11030 (516) 627-1838 (516) 627-3739 (516) 627-5364
  • 70 Beechwood Ave, Manhasset, NY 11030 (516) 627-5364
  • 17 Woodbury Ct, Princeton Jct, NJ 08550
  • Princeton Junction, NJ
  • Great Neck, NY
  • Livingston, NJ
  • Du Bois, PA
  • Little Neck, NY
  • Union, NJ

Industries

Pharmaceuticals

Resumes

Resumes

Youzhi Tong Photo 1

Independent Pharmaceuticals Professional

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Location:
Greater New York City Area
Industry:
Pharmaceuticals

Publications

Us Patents

Mutants Of Thymidylate Synthase And Uses Thereof

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US Patent:
6416987, Jul 9, 2002
Filed:
Aug 4, 1999
Appl. No.:
09/367007
Inventors:
Xinyue Liu-Chen - New York NY
Youzhi Tong - Union NJ
Joseph R. Bertino - Branford CT
Debabrata Banerjee - Bellerose NY
Assignee:
Sloan Kettering Institute for Cancer Research - New York NY
International Classification:
C12N 912
US Classification:
435193, 4352523, 4353201, 435325, 536 232
Abstract:
The present invention provides a mutated human TS, said mutated synthase differing from wild type TS at amino acid residue 49, amino acid residue 52, amino acid residue 108, amino acid residue 221 or amino acid residue 225. Also provided is cDNA mutated human TSs and novel vectors and host cells and methods of using the mutated human TSs.

Bifunctional Compound, Preparation Method Therefor, And Use Thereof

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US Patent:
20230054270, Feb 23, 2023
Filed:
Sep 9, 2022
Appl. No.:
17/942094
Inventors:
- Suzhou, CN
Youzhi TONG - New York NY, US
Assignee:
SUZHOU KINTOR PHARMACEUTICALS, INC. - Suzhou
International Classification:
C07D 417/14
A61P 17/10
A61P 17/14
Abstract:
The present invention relates to a bifunctional compound, a preparation method therefor, and a use thereof, wherein the bifunctional compound comprises an E3 ubiquitin ligase-binding moiety; a target protein-binding moiety that binds to an androgen receptor; and a linking moiety that links the E3 ubiquitin ligase-binding moiety and the target protein-binding moiety. The bifunctional compound of the present application allows the androgen receptor to be positioned adjacent to the ubiquitin ligase, so as to achieve the degradation or inhibition of the androgen receptor.

Mechanistic Target Of Rapamycin Signaling Pathway Inhibitors And Therapeutic Applications Thereof

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US Patent:
20200181147, Jun 11, 2020
Filed:
May 17, 2017
Appl. No.:
16/313081
Inventors:
- Suzhou, Jiangsu, CN
Youzhi TONG - Little Neck NY, US
Assignee:
SUZHOU KINTOR PHARMACEUTICALS, INC. - Suzhou, Jiangsu
International Classification:
C07D 487/04
C07D 519/00
Abstract:
Selective mTOR inhibitors of formulas (I)-(III), processes for their preparation, pharmaceutical compositions containing them, and their use in the treatment of diseases and disorders, arising from abnormal cell growth, functions, or behaviors mediated by an mTOR kinase and/or one or more PI3K enzyme, are provided. Such diseases and disorder include cancer, immune disorders, cardiovascular disease, viral infection, inflammation, metabolism/endocrine function disorders and neurological disorders.

Dihydropyridophthalazinone Compounds As Inhibitors Of Poly (Adp-Ribose) Polymerase (Parp) For Treatment Of Diseases And Method Of Use Thereof

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US Patent:
20200002337, Jan 2, 2020
Filed:
Feb 9, 2018
Appl. No.:
16/487919
Inventors:
- Suzhou, Jiangsu, CN
Youzhi TONG - Little Neck NY, US
Assignee:
SUZHOU KINTOR PHARMACEUTICALS, INC. - Suzhou, Jiangsu
International Classification:
C07D 471/06
A61P 35/00
Abstract:
The present invention provides novel dihydropyridophthalazinone compounds of Formula (I) as PARP inhibitors, and their pharmaceutically acceptable salts, solvates, hydrates, prodrugs and metabolites thereof, the preparation thereof, and the use of such compounds to treat DNA repair dysregulation diseases and conditions such as cancer. The present provides therapeutic applications for the treatment of stroke, myocardial infarction, neurodegenerative diseases, ovarian cancer, breast cancer, prostate cancer, lung cancer, colorectal cancer, and melanoma.
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Youzhi Tong from Manhasset, NY, age ~62 Get Report