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Yingzi Xue

from Princeton Junction, NJ
Age ~59
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Also known as:
Ying Zi Xue, Yingzi Xihong, Yingzi Zue, Ying-Zi Xue, Xue Yingzi, Yang Xihong, Xihong Yang
Related to:
Joyce Y Chow, 51
Connected to:
Amy C Xue, 36Cathleen S Xue, 49Chenming Xue, 42Cherry Y Xue, 43Cindy Z Xue, 79Emily Xue, 35Feifei S Xue, 40Fengtian Xue, 48Gang Xue, 70Jenny G Xue, 76

Yingzi Xue Phones & Addresses

  • Princeton Junction, NJ
  • Middletown, NY
  • 1 Glen Rd, Ardsley, NY 10502 (914) 591-5134
  • 3 Paluga Ln, Bar Harbor, ME 04609
  • Yonkers, NY
  • Irvington, NY
  • Jersey City, NJ
  • Westchester, NY
  • New York, NY
  • Nutley, NJ
  • Baltimore, MD
  • 1 Glen Rd, Ardsley, NY 10502 (914) 263-5328

Work

Position: Professional/Technical

Education

Degree: Graduate or professional degree

Emails

y***[email protected]

Publications

Us Patents

Genetically Modified Major Histocompatibility Complex Animals

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US Patent:
20130185819, Jul 18, 2013
Filed:
Mar 11, 2013
Appl. No.:
13/793812
Inventors:
Andrew J. MURPHY - Croton-on-Hudson NY, US
Cagan GURER - Valhalla NY, US
John MCWHIRTER - Tarrytown NY, US
Vera VORONINA - Thornwood NY, US
Faith HARRIS - Mamaroneck NY, US
Sean STEVENS - San Francisco CA, US
Yingzi XUE - Ardsley NY, US
Assignee:
REGENERON PHARMACEUTICALS, INC. - Tarrytown NY
International Classification:
A01K 67/027
US Classification:
800 18, 800 14, 536 234
Abstract:
The invention provides genetically modified non-human animals that express chimeric human/non-human MHC I polypeptide and/or human or humanized β2 microglobulin polypeptide, as well as embryos, cells, and tissues comprising the same. Also provided are constructs for making said genetically modified animals and methods of making the same. Methods of using the genetically modified animals to study various aspects of human immune system are provided.

Humanized Il-4 And Il-4Ra Animals

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US Patent:
20230027494, Jan 26, 2023
Filed:
Aug 30, 2022
Appl. No.:
17/823186
Inventors:
- Tarrytown NY, US
Yingzi Xue - Ardsley NY, US
Andrew J. Murphy - Croton-on-Hudson NY, US
Sean Stevens - Del Mar CA, US
Assignee:
Regeneron Pharmaceuticals, Inc. - Tarrytown NY
International Classification:
A01K 67/027
C07K 14/54
C07K 14/715
Abstract:
Non-human animals comprising a human or humanized IL-4 and/or IL-4Rα nucleic acid sequence are provided. Non-human animals that comprise a replacement of the endogenous IL-4 gene and/or IL-4Rα gene with a human IL-4 gene and/or IL-4Rα gene in whole or in part, and methods for making and using the non-human animals, are described. Non-human animals comprising a human or humanized IL-4 gene under control of non-human IL-4 regulatory elements is also provided, including non-human animals that have a replacement of non-human IL-4-encoding sequence with human IL-4-encoding sequence at an endogenous non-human IL-4 locus. Non-human animals comprising a human or humanized IL-4Rα gene under control of non-human IL-4Rα regulatory elements is also provided, including non-human animals that have a replacement of non-human IL-4Rα-encoding sequence with human or humanized IL-4Rα-encoding sequence at an endogenous non-human C IL-4Rα locus. Non-human animals comprising human or humanized IL-4 gene and/or IL-4Rα sequences, wherein the non-human animals are rodents, e.g., mice or rats, are provided.

Humanized Il-4 And Il-4Ra Animals

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US Patent:
20210368753, Dec 2, 2021
Filed:
Aug 5, 2021
Appl. No.:
17/394492
Inventors:
- Tarrytown NY, US
Yingzi Xue - Ardsley NY, US
Andrew J. Murphy - Croton-on-Hudson NY, US
Sean Stevens - Del Mar CA, US
Assignee:
Regeneron Pharmaceuticals, Inc. - Tarrytown NY
International Classification:
A01K 67/027
C07K 14/54
C07K 14/715
Abstract:
Non-human animals comprising a human or humanized IL-4 and/or IL-4Rα nucleic acid sequence are provided. Non-human animals that comprise a replacement of the endogenous IL-4 gene and/or IL-4Rα gene with a human IL-4 gene and/or IL-4Rα gene in whole or in part, and methods for making and using the non-human animals, are described. Non-human animals comprising a human or humanized IL-4 gene under control of non-human IL-4 regulatory elements is also provided, including non-human animals that have a replacement of non-human IL-4-encoding sequence with human IL-4-encoding sequence at an endogenous non-human IL-4 locus. Non-human animals comprising a human or humanized IL-4Rα gene under control of non-human IL-4Rα regulatory elements is also provided, including non-human animals that have a replacement of non-human IL-4Rα-encoding sequence with human or humanized IL-4Rα-encoding sequence at an endogenous non-human C IL-4Rα locus. Non-human animals comprising human or humanized IL-4 gene and/or IL-4Rα sequences, wherein the non-human animals are rodents, e.g., mice or rats, are provided.

Genetically Modified Major Histocompatibility Complex Animals

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US Patent:
20200375159, Dec 3, 2020
Filed:
Aug 6, 2020
Appl. No.:
16/986844
Inventors:
- Tarrytown NY, US
Andrew J. Murphy - Croton-on-Hudson NY, US
Cagan Gurer - Chappaqua NY, US
John McWhirter - Hastings-on-Hudson NY, US
Vera Voronina - Sleepy Hollow NY, US
Faith Harris - Mamaroneck NY, US
Sean Stevens - Del Mar CA, US
Yingzi Xue - Ardsley NY, US
International Classification:
A01K 67/027
Abstract:
The invention provides genetically modified non-human animals that express chimeric human/non-human MHC I polypeptide and/or human or humanized β2 microglobulin polypeptide, as well as embryos, cells, and tissues comprising the same. Also provided are constructs for making said genetically modified animals and methods of making the same. Methods of using the genetically modified animals to study various aspects of human immune system are provided.

Humanized Il-4 And Il-4Ra Animals

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US Patent:
20200022344, Jan 23, 2020
Filed:
Oct 7, 2019
Appl. No.:
16/594537
Inventors:
- Tarrytown NY, US
Yingzi Xue - Ardsley NY, US
Andrew J. Murphy - Croton-on-Hudson NY, US
Sean Stevens - Del Mar CA, US
Assignee:
Regeneron Pharmaceuticals, Inc. - Tarrytown NY
International Classification:
A01K 67/027
C07K 14/54
C07K 14/715
Abstract:
Non-human animals comprising a human or humanized IL-4 and/or IL-4Rα nucleic acid sequence are provided. Non-human animals that comprise a replacement of the endogenous IL-4 gene and/or IL-4Rα gene with a human IL-4 gene and/or IL-4Rα gene in whole or in part, and methods for making and using the non-human animals, are described. Non-human animals comprising a human or humanized IL-4 gene under control of non-human IL-4 regulatory elements is also provided, including non-human animals that have a replacement of non-human IL-4-encoding sequence with human IL-4-encoding sequence at an endogenous non-human IL-4 locus. Non-human animals comprising a human or humanized IL-4Rα gene under control of non-human IL-4Rα regulatory elements is also provided, including non-human animals that have a replacement of non-human IL-4Rα-encoding sequence with human or humanized IL-4Rα-encoding sequence at an endogenous non-human C IL-4Rα locus. Non-human animals comprising human or humanized IL-4 gene and/or IL-4Rα sequences, wherein the non-human animals are rodents, e.g., mice or rats, are provided.

Genetically Modified Major Histocompatibility Complex Animals

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US Patent:
20180288986, Oct 11, 2018
Filed:
Jun 21, 2018
Appl. No.:
16/015159
Inventors:
- Tarrytown NY, US
Andrew J. Murphy - Croton-on-Hudson NY, US
Cagan Gurer - Chappaqua NY, US
John McWhirter - Hastings-on-Hudson NY, US
Vera Voronina - Sleepy Hollow NY, US
Faith Harris - Mamaroneck NY, US
Sean Stevens - Del Mar CA, US
Yingzi Xue - Ardsley NY, US
International Classification:
A01K 67/027
Abstract:
The invention provides genetically modified non-human animals that express chimeric human/non-human MHC I polypeptide and/or human or humanized β2 microglobulin polypeptide, as well as embryos, cells, and tissues comprising the same. Also provided are constructs for making said genetically modified animals and methods of making the same. Methods of using the genetically modified animals to study various aspects of human immune system are provided.

Genetically Modified Major Histocompatibility Complex Mice

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US Patent:
20180116190, May 3, 2018
Filed:
Dec 12, 2017
Appl. No.:
15/839655
Inventors:
- Tarrytown NY, US
Cagan Gurer - Chappaqua NY, US
Andrew J. Murphy - Croton-on-Hudson NY, US
Lynn Macdonald - Harrison NY, US
Yingzi Xue - Ardsley NY, US
International Classification:
A01K 67/027
C07K 14/74
C07K 14/73
C07K 14/705
C12N 15/85
Abstract:
The invention provides genetically modified non-human animals that express chimeric human/non-human MHC I and MHC II polypeptides and/or human or humanized β2 microglobulin polypeptide, as well as embryos, cells, and tissues comprising the same. Also provided are constructs for making said genetically modified animals and methods of making the same. Methods of using the genetically modified animals to study various aspects of human immune system are provided.

Humanized Il-4 And Il-4Ra Animals

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US Patent:
20180000056, Jan 4, 2018
Filed:
Sep 15, 2017
Appl. No.:
15/705326
Inventors:
- Tarrytown NY, US
Yingzi Xue - Ardsley NY, US
Andrew J. Murphy - Croton-on-Hudson NY, US
Sean Stevens - Del Mar CA, US
Assignee:
REGENERON PHARMACEUTICALS, INC. - Tarrytown NY
International Classification:
A01K 67/027
C07K 14/715
C07K 14/54
Abstract:
Non-human animals comprising a human or humanized IL-4 and/or IL-4Rα nucleic acid sequence are provided. Non-human animals that comprise a replacement of the endogenous IL-4 gene and/or IL-4Rα gene with a human IL-4 gene and/or IL-4Rα gene in whole or in part, and methods for making and using the non-human animals, are described. Non-human animals comprising a human or humanized IL-4 gene under control of non-human IL-4 regulatory elements is also provided, including non-human animals that have a replacement of non-human IL-4-encoding sequence with human IL-4-encoding sequence at an endogenous non-human IL-4 locus. Non-human animals comprising a human or humanized IL-4Rα gene under control of non-human IL-4Rα regulatory elements is also provided, including non-human animals that have a replacement of non-human IL-4Rα-encoding sequence with human or humanized IL-4Rα-encoding sequence at an endogenous non-human C IL-4Rα locus. Non-human animals comprising human or humanized IL-4 gene and/or IL-4Rα sequences, wherein the non-human animals are rodents, e.g., mice or rats, are provided.
Control profile
Yingzi Xue from Princeton Junction, NJ, age ~59 Get Report