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Ying Xu Homan

from Ambler, PA
Age ~58
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Also known as:
Ying X Homan, Ying X Xu, Xu U Ying, Joseph Homan, Yin G Xu
Phone and address:
1626 Norristown Rd, Prospectville, PA 19002
(267) 305-2236
Related to:
Xue Hao, 82Lun Tseng YiAllison E Spinelli, 48Miles G Homan, 73Jie Xu, 57Aimee L Homan, 45Bo Yang Yingbo, 61Joseph W Homan, 52Lewie Homan, 35June A Homan, 70
Connected to:
Alyssa M Homan, 34Andy J Homan, 47Annamaria Homan, 67Audrey Homan, 77Billy B Homan, 75Caroline W Homan, 55Casey R Homan, 32Catherine M Homan, 65Claudia J Homan, 88Deborah A Homan, 58

Ying Homan Phones & Addresses

  • 1626 Norristown Rd, Ambler, PA 19002 (267) 305-2236
  • Maple Glen, PA
  • Clementon, NJ
  • 693 Boxwood Rd, Upper Chichester, PA 19014 (610) 485-9762
  • Fairbanks, AK
  • Philadelphia, PA
  • Montgomery, PA
  • 1626 Norristown Rd, Ambler, PA 19002 (267) 446-8656

Work

Position: Medical Professional

Education

Degree: Associate degree or higher

Resumes

Resumes

Ying Homan Photo 1

Ying Homan

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Location:
1626 Norristown Rd, Ambler, PA 19002
Industry:
Biotechnology
Work:
Aderans Res. Inst. Inc
Senior Scientist
Aderans Research Institute 2005 - 2010
Senior Scientist
Skills:
Cell
Stem Cells
Cell Culture
Biotechnology
Tissue Culture
Cell Biology
Flow Cytometry
In Vitro
Tissue Engineering
Qpcr
Elisa
Life Sciences
Molecular Biology
Multi Color Flow Cytometry
Languages:
Mandarin
Ying Homan Photo 2

Senior Scientist

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Location:
Ambler, PA
Work:
Merck
Senior Scientist

Publications

Us Patents

Biomarkers For Trichogenicity

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US Patent:
20100291580, Nov 18, 2010
Filed:
Dec 18, 2008
Appl. No.:
12/808623
Inventors:
Satish Parimoo - Bridgewater NJ, US
Honghua Yang - Cherry Hill NJ, US
Ying Homan - Ambler PA, US
Wei Chen - Havertown PA, US
Ying Zheng - West Chester PA, US
Kurt Stenn - Princeton NJ, US
International Classification:
C12Q 1/68
G01N 33/566
C12N 15/79
US Classification:
435 6, 435 721, 435375
Abstract:
Biomarkers for identifying trichogenic cells have been identified. The biomarkers include microRNA as wells as mRNA and proteins. Certain biomarkers are upregulated in trichogenic cells compared to non-trichogenic cells; whereas, other biomarkers are down-regulated in trichogenic cells compared to non-trichogenic cells. The cells can be dermal cells, epidermal cells, or a combination thereof. Preferably the cells are mammalian, more preferably the cells are human. One embodiment provides a method for selecting trichogenic cells by assaying the cells for expression of one or more biomarkers for trichogenicity, and selecting the cells having increased expression of the one or more biomarkers relative to a control, wherein increased expression of the a biomarker in the cells is indicative of trichogenicity. Preferably, the one or more biomarkers are selected from the group consisting of hsa-miR-200c, hsa-miR-205, hsa-miR-200a*, hsa-miR-200a, hsa-miR-141, hsa-miR-182, DEPDC1, hFLEG1, ESM1, TOME-1, THBD and combinations thereof.

Methods For Increasing Trichogenicity Of Dermal Cells

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US Patent:
20120022433, Jan 26, 2012
Filed:
Sep 30, 2011
Appl. No.:
13/250536
Inventors:
Ying Zheng - West Chester PA, US
Arben Nace - Landenberg PA, US
Luke Sergott - Philadelphia PA, US
Michael Ensslin - Atlanta GA, US
Ying Homan - Ambler PA, US
Kurt Stenn - Princeton NJ, US
International Classification:
A61M 37/00
C12N 5/071
US Classification:
604 20, 604 22, 604187, 435325
Abstract:
Methods for increasing trichogenic activity of populations of dermal cells by inducing local trauma to skin tissue that serves as a source of the dermal cells are provided. Methods for obtaining dermal cells with increased trichogenic activity and for using the disclosed dermal cells to implant into a mammalian host at a site of desired follicle generation are also provided.

Methods And Compositions For Increasing Trichogenic Potency Of Dermal Cells

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US Patent:
20120095445, Apr 19, 2012
Filed:
Jun 16, 2010
Appl. No.:
13/378732
Inventors:
Ying Zheng - West Chester PA, US
Marylene Boucher - St-Ignace-de-Loyola, CA
Ying Homan - Ambler PA, US
Charles Hollow - Scranton PA, US
Polina Mamontov - Philadelphia PA, US
Kurt Stenn - Princeton NJ, US
International Classification:
A61K 35/12
A61P 17/14
A61M 37/00
C12N 5/071
US Classification:
604522, 435375, 435366, 424 937
Abstract:
Methods and compositions for increasing trichogenicity of cells in culture are provided. One embodiment provides culturing dissociated mammalian dermal cells in vitro in the presence of an effective amount of one or more sonic hedgehog (Shh) pathway agonists to increase the trichogenicity of the dissociated mammalian dermal cells compared to untreated dissociated mammalian dermal cells. The cell culture optionally includes epidermal cells. Preferred Shh agonists include, but are not limited to CUR-0236715 and CUR-0201365 available from Curis, Inc. Trichogenicity is measured using the Aderans Hair Patch Assay™. The cultured dermal cells can be maintained in culture in the presence of the one or more Shh agonists for at least 1 to 7 or more days prior to harvest. The treated, cultured dermal cells can be used to treat hair loss in a mammalian subject, preferably a human, by implanting them in an effective amount to induce hair follicle formation.

Methods For Increasing Trichogenicity Of Dermal Cells

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US Patent:
20100179492, Jul 15, 2010
Filed:
Jan 14, 2009
Appl. No.:
12/353699
Inventors:
Ying Zheng - West Chester PA, US
Arben Nace - Landenberg PA, US
Luke Sergott - Philadephia PA, US
Michael Ensslin - Wynnewood PA, US
Ying Homan - Ambler PA, US
Kurt Stenn - Princeton NJ, US
International Classification:
A61M 35/00
C12N 5/08
A61B 17/50
A61B 18/20
A61B 18/04
A61K 35/12
US Classification:
604290, 435371, 606133, 606 1, 606 2, 606 27, 424 937
Abstract:
Methods for increasing trichogenic activity of populations of dermal cells by inducing local trauma to skin tissue that serves as a source of the dermal cells are provided. Methods for obtaining dermal cells with increased trichogenic activity and for using the disclosed dermal cells to implant into a mammalian host at a site of desired follicle generation are also provided.
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Ying Xu Homan from Ambler, PA, age ~58 Get Report