Yijun Pan Phones & Addresses
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414 Chesterton Ave, Belmont, CA 94002 (213) 270-5871
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Holly Springs, NC
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San Mateo, CA
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West Covina, CA
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Los Angeles, CA
Publications
Us Patents
Perfluoro Sulfonyl Halides And Related Species As Polymer Support Modifiers
View pageUS Patent:
20030124612, Jul 3, 2003
Filed:
Jan 11, 2002
Appl. No.:
10/044784
Inventors:
Christopher Holmes - Saratoga CA, US
Yijun Pan - Fremont CA, US
Yijun Pan - Fremont CA, US
International Classification:
G01N033/53
C08F291/00
C08F008/36
C08F291/00
C08F008/36
US Classification:
435/007100, 525/254000, 525/261000
Abstract:
Activated Supports, support-bound activators, strongly acidic supports, and silylating supports are provided; the activated support having the formula: wherein L is a linking group component; X is F, Cl, OH, and trisubstituted silyloxy; and the shaded circle represents a solid or semi-solid support. Methods of using the activated supports in solid phase organic synthesis are also provided.
Compounds And Peptides That Bind The Kgf Receptor
View pageUS Patent:
20090042802, Feb 12, 2009
Filed:
Jun 20, 2008
Appl. No.:
12/143684
Inventors:
YIJUN PAN - Union City CA, US
Christopher Holmes - Saratoga CA, US
Yvonne Angell - San Carlos CA, US
Christopher Holmes - Saratoga CA, US
Yvonne Angell - San Carlos CA, US
International Classification:
A61K 38/08
A61K 38/10
C07K 7/06
C07K 7/08
C07K 7/64
A61K 38/10
C07K 7/06
C07K 7/08
C07K 7/64
US Classification:
514 13, 530326, 530327, 530328, 530317, 514 14, 514 15, 514 16
Abstract:
The present invention relates to peptide compounds that bind the KGF receptor. The invention also relates to therapeutic methods using such peptide compounds to treat disorders associated with defective or insufficient epithelial cell proliferation. Pharmaceutical compositions, which comprise the peptide compounds of the invention, and dosages are also provided.
Nitrogen-Based Linkers For Attaching Modifying Groups To Polypeptides And Other Macromolecules
View pageUS Patent:
20090048147, Feb 19, 2009
Filed:
Jan 30, 2008
Appl. No.:
12/022926
Inventors:
Christopher P. Holmes - Saratoga CA, US
Anjan Chakrabarti - Gurgaon, IN
Brian T. Frederick - Ben Lomond CA, US
Yijun Pan - Union City CA, US
Yaohua S. Dong - San Francisco CA, US
Ashok Bhandari - Cupertino CA, US
Anjan Chakrabarti - Gurgaon, IN
Brian T. Frederick - Ben Lomond CA, US
Yijun Pan - Union City CA, US
Yaohua S. Dong - San Francisco CA, US
Ashok Bhandari - Cupertino CA, US
Assignee:
Affymax, Inc. - Palo Alto CA
International Classification:
C07C 233/05
C07C 229/04
C07K 7/02
A61K 38/02
C07C 229/04
C07K 7/02
A61K 38/02
US Classification:
514 2, 564192, 562567, 530323
Abstract:
The present invention relates to a compound comprising a peptide moiety, a linker moiety and a water-soluble polymer moiety such as a poly(ethylene glycol) moiety. The linker moiety is between the peptide moiety and the water-soluble polymer moiety. In certain embodiments, the linker moiety has the structure:wherein α, β, and γ are each integers whose values are independently selected. In other embodiments the linker moiety has the following structure:wherein κ, ρ, and τ are each integers whose values are independently selected. In other embodiments the linker moiety has the following structure:wherein χ, φ, γ, and η are each integers whose values are independently selected. Alternatively, the linker structure may have the following structure:wherein λ and μ are each integers whose values are independently selected.
Perfluoro Sulfonyl Halides And Related Species As Polymer Support Modifiers
View pageUS Patent:
20110028751, Feb 3, 2011
Filed:
Apr 15, 2010
Appl. No.:
12/760840
Inventors:
Christopher Holmes - Saratoga CA, US
Yijun Pan - Union City CA, US
Yijun Pan - Union City CA, US
Assignee:
GE HEALTHCARE LIMITED - Buckinghamshire
International Classification:
C07C 303/02
C07C 317/00
C07C 309/02
C07C 317/00
C07C 309/02
US Classification:
558 44, 568 28, 562 41
Abstract:
Activated Supports, support-bound activators, strongly acidic supports, and silylating supports are provided; the activated support having the formula:wherein L is a linking group component; X is F, Cl, OH, and trisubstituted silyloxy; and the shaded circle represents a solid or semi-solid support. Methods of using the activated supports in solid phase organic synthesis are also provided.
Nitrogen-Based Linkers For Attaching Modifying Groups To Polypeptides And Other Macromolecules
View pageUS Patent:
20120165275, Jun 28, 2012
Filed:
Dec 21, 2011
Appl. No.:
13/333570
Inventors:
Christopher P. Holmes - Saratoga CA, US
Anjan Chakrabarti - Gurgaon, IN
Brian T. Frederick - Ben Lomond CA, US
Yijun Pan - Fremont CA, US
Yaohua S. Dong - San Francisco CA, US
Ashok Bhandari - Cupertino CA, US
Anjan Chakrabarti - Gurgaon, IN
Brian T. Frederick - Ben Lomond CA, US
Yijun Pan - Fremont CA, US
Yaohua S. Dong - San Francisco CA, US
Ashok Bhandari - Cupertino CA, US
Assignee:
AFFYMAX, INC. - Palo Alto CA
International Classification:
A61K 38/16
C07K 14/00
C07D 207/46
C07D 207/12
C07K 14/00
C07D 207/46
C07D 207/12
US Classification:
514 214, 548520, 530326, 548542
Abstract:
Compounds comprising a peptide moiety, a linker moiety and a water-soluble polymer moiety such as a poly(ethylene glycol) moiety are disclosed. Various linker moieties for use in these compounds are also disclosed, along methods for their synthesis.