Search

Yehia S Mechref

from Lubbock, TX
Age ~58

Yehia Mechref Phones & Addresses

  • 3306 105Th St, Lubbock, TX 79423 (806) 368-0615
  • 3906 105Th St, Lubbock, TX 79423 (806) 368-0615
  • 931 Woodbridge Dr, Bloomington, IN 47408 (812) 336-4892
  • 2894 Hunters Gln, Bloomington, IN 47401 (812) 336-4892
  • Stillwater, OK
  • Washington, DC

Work

Position: Professional/Technical

Education

Degree: High school graduate or higher

Publications

Us Patents

High Temperature Incubation System And Method For Small Volumes

View page
US Patent:
6905076, Jun 14, 2005
Filed:
Aug 19, 2003
Appl. No.:
10/643501
Inventors:
Yunping Huang - Urbana IL, US
Yehia S. Mechref - Bloomington IN, US
Milos V. Novotny - Bloomington IN, US
Assignee:
Advanced Research and Technology Institute, Inc. - Indianapolis IN
International Classification:
A01K031/20
US Classification:
237 14, 236 2
Abstract:
A system and method of incubating a liquid is provided. The system is well-suited for incubating small volumes of liquid at high temperatures. The liquid may be a reaction mixture comprising a glycoprotein. During the incubation process, oligosaccharides may be removed from the glycoprotein.

Device For Placement Of Effluent

View page
US Patent:
6911182, Jun 28, 2005
Filed:
Oct 18, 2002
Appl. No.:
10/274247
Inventors:
Tony J. Tegeler - Bloomington IN, US
Yehia Mechref - Bloomington IN, US
Kirk S. Boraas - Bloomington IN, US
James P. Reilly - Bloomington IN, US
Milos V. Novotny - Bloomington IN, US
Assignee:
Indiana University Research and Technology Corporation - Indianapolis IN
International Classification:
B01L003/02
B01L011/00
G01N015/06
G01N033/00
G01N033/48
US Classification:
422100, 422 50, 422 63, 422 64, 422 65, 422 66, 422 67, 422 681, 422 70, 422 81, 422 82, 422 99, 422101, 422103, 436 43, 436 44, 436 46, 436 47, 436174, 436180, 4352831, 4352864, 4352871, 4352873
Abstract:
A device for placement of effluent comprises a substrate positioner, a deposition conduit, and a conduit positioner. The substrate positioner supports and positions a substrate on which effluent exiting from the deposition conduit is to be deposited. The conduit positioner moves an exit end of the deposition conduit relative to the substrate.

Permethylation Of Oligosaccharides

View page
US Patent:
7968345, Jun 28, 2011
Filed:
Aug 10, 2010
Appl. No.:
12/853759
Inventors:
Pilsoo Kang - Bloomington IN, US
Yehia S. Mechref - Bloomington IN, US
Milos V. Novotny - Bloomington IN, US
Assignee:
Indiana University Research and Technology Corporation - Indianapolis IN
International Classification:
G01N 33/00
C12N 9/26
US Classification:
436 94, 422129, 422 681, 422102, 436 43, 436174, 435201
Abstract:
A solid-phase permethylation procedure is described. For example, solid-phase permethylation can be utilized to prepare permethylated linear and branched, neutral and sialylated oligosaccharides, which can be analyzed by MALDI-MS.

Fluid Treatment Device

View page
US Patent:
20040077101, Apr 22, 2004
Filed:
Oct 18, 2002
Appl. No.:
10/277556
Inventors:
Tony Tegeler - Bloomington IN, US
Yehia Mechref - Bloomington IN, US
Milos Novotny - Bloomington IN, US
International Classification:
G01N001/00
US Classification:
436/174000, 436/173000, 422/099000, 422/100000
Abstract:
A fluid treatment device is disclosed for mixing first and second fluids. The first fluid may be a treatment liquid that is contained in a container and that is used to change a property, such as the pH, density or ionic strength, of the second fluid. In some illustrative embodiments, the fluid treatment device is used to create an effluent by adding a buffer material and/or a matrix material to an analyte for subsequent MALDI MS analysis of the effluent. A mixing space is defined in a container between ends of first and second conduits. In some embodiments, a junction member couples together the ends of the first and second conduits. The junction member has a main passage that receives the ends of the first and second conduits. The junction member has at least one opening that provides fluid communication between an interior region of the container and the mixing space.

Method Of Preparation Of Oligosaccharides

View page
US Patent:
20040096933, May 20, 2004
Filed:
Sep 19, 2003
Appl. No.:
10/664462
Inventors:
Yunping Huang - Urbana IL, US
Tomonori Konse - Hiratsuka-shi, JP
Yehia Mechref - Bloomington IN, US
Milos Novotny - Bloomington IN, US
International Classification:
C12P021/06
C12P019/04
C08B037/00
US Classification:
435/068100, 435/101000, 536/053000
Abstract:
The invention provides a method of cleaving an O-linked oligosaccharide from a glycoprotein. The method comprises the steps of contacting a composition comprising a glycoprotein, wherein the glycoprotein comprises O-linked oligosaccharides, with a solution comprising a borane-ammonia complex to form a mixture comprising the glycoprotein and the borane-ammonia complex, incubating the mixture for a period of time sufficient to cleave the linked oligosaccharides from the glycoprotein, and forming a mixture comprising oligosaccharide alditol products and deglycosylated protein by-products.

Glycoprotein Cleavage Protocol For Oligosaccharide Analysis

View page
US Patent:
20040096948, May 20, 2004
Filed:
Aug 19, 2003
Appl. No.:
10/643502
Inventors:
Yunping Huang - Urbana IL, US
Yehia Mechref - Bloomington IN, US
Milos Novotny - Bloomington IN, US
International Classification:
C12P019/04
C08B037/00
US Classification:
435/101000, 536/123000, 536/018700
Abstract:
An ammonium-based -elimination cleavage of linked oligosaccharides from glycoproteins is described. The method enables the isolation of glycoprotein-derived oligosaccharides having a reducing end which enables subsequent derivatization for chromatographic and/or mass spectral analysis. The described glycoprotein cleavage protocol enables structural investigations using low microgram quantities of glycoproteins.

High Temperature Incubation System And Method For Small Volumes

View page
US Patent:
20050239212, Oct 27, 2005
Filed:
Jun 13, 2005
Appl. No.:
11/151144
Inventors:
Yunping Huang - Urbana IL, US
Yehia Mechref - Bloomington IN, US
Milos Novotny - Bloomington IN, US
International Classification:
G01N001/00
US Classification:
436174000, 435303100, 422099000
Abstract:
A system and method of incubating a liquid is provided. The system is well-suited for incubating small volumes of liquid at high temperatures. The liquid may be a reaction mixture comprising a glycoprotein. During the incubation process, oligosaccharides may be removed from the glycoprotein.

Permethylation Of Oligosaccharides

View page
US Patent:
20080274557, Nov 6, 2008
Filed:
Mar 3, 2006
Appl. No.:
11/817436
Inventors:
Pilsoo Kang - Bloomington IN, US
Yehia S. Mechref - Bloomington IN, US
Milos V. Novotny - Bloomington IN, US
International Classification:
G01N 33/00
B01J 19/00
C07H 1/00
US Classification:
436 94, 422129, 536 221, 422 681
Abstract:
A solid-phase permethylation procedure is described. For example, solid-phase permethylation can be utilized to prepare permethylated linear and branched, neutral and sialylated oligosaccharides, which can be analyzed by MALDI-MS.
Yehia S Mechref from Lubbock, TX, age ~58 Get Report