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Yann Echelard

from Jamaica Plain, MA
Age ~61

Yann Echelard Phones & Addresses

  • 54 Slocum Rd, Jamaica Plain, MA 02130 (617) 522-4370
  • 241 Perkins St UNIT I202, Jamaica Plain, MA 02130
  • 248 Moss Hill Rd, Jamaica Plain, MA 02130 (617) 522-4370
  • 12 Colliston Rd, Brighton, MA 02135
  • West Roxbury, MA
  • Brookline, MA
  • Arlington, MA
  • Seattle, WA
  • 54 Slocum Rd, Jamaica Plain, MA 02130

Work

Company: Gtc biotherapeutics Jul 2010 Position: Vp corporate and technology development

Education

Degree: PhD School / High School: Université de Montréal 1984 to 1989 Specialities: Microbiologie et Immunologie

Skills

Biopharmaceuticals • Biotechnology • Lifesciences • Drug Development • Pharmaceutical Industry • Fda • Commercialization • Molecular Biology • Technology Transfer • Drug Discovery • Gmp • Clinical Development • R&D • Oncology • Medical Devices • Immunology • Vaccines • Developmental Biology • Laboratory • Validation

Languages

English • French • Spanish

Interests

Social Services • Children • Civil Rights and Social Action • Environment • Science and Technology • Health

Industries

Pharmaceuticals

Resumes

Resumes

Yann Echelard Photo 1

Operating Partner

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Location:
Framingham, MA
Industry:
Pharmaceuticals
Work:
GTC Biotherapeutics since Jul 2010
VP Corporate and Technology Development

GTC Biotherapeutics 2002 - Jul 2010
VP Research and Development

Genzyme Transgenics Corporation 1998 - 2002
Director of Embryology

Genzyme Transgenics Corporation 1994 - 1998
Scientist

Harvard University, Dept of Molecular and Cellular Biology 1993 - 1993
Postdoctoral Fellow
Education:
Université de Montréal 1984 - 1989
PhD, Microbiologie et Immunologie
Université de Montréal 1981 - 1984
B. Sc., Microbiologie et Immunologie
Collège Français 1977 - 1981
High School
Skills:
Biopharmaceuticals
Biotechnology
Lifesciences
Drug Development
Pharmaceutical Industry
Fda
Commercialization
Molecular Biology
Technology Transfer
Drug Discovery
Gmp
Clinical Development
R&D
Oncology
Medical Devices
Immunology
Vaccines
Developmental Biology
Laboratory
Validation
Interests:
Social Services
Children
Civil Rights and Social Action
Environment
Science and Technology
Health
Languages:
English
French
Spanish

Publications

Us Patents

Transgenically Produced Prolactin

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US Patent:
6545198, Apr 8, 2003
Filed:
Jan 24, 2000
Appl. No.:
09/490657
Inventors:
Yann Echelard - Brookline MA
Brian Wilburn - Boston MA
Assignee:
Genzyme Transgenics Corporation - Framingham MA
International Classification:
C12P 2100
US Classification:
800 4, 800 14, 800 8, 800 21, 800 7
Abstract:
Transgenically produced prolactin and methods of making and using transgenically produced prolactin.

Transgenic And Cloned Mammals

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US Patent:
20030177513, Sep 18, 2003
Filed:
Apr 25, 2003
Appl. No.:
10/423792
Inventors:
Yann Echelard - Jamaica Plain MA, US
Esmail Behbodi - Shrewsbury MA, US
Carol Ziomek - Milford MA, US
William Gavin - Dudley MA, US
David Melican - Fiskdale MA, US
International Classification:
A01K067/027
US Classification:
800/014000, 800/021000
Abstract:
The invention features cloned and transgenic mammals, e.g., goats, which are made by introducing the genome of a somatic cell into an enucleated oocyte, preferably a naturally matured oocyte which in telophase, to form a reconstructed embryo.

Method For The Rapid Selection Of Homozygous Primary Cell Lines For The Production Of Transgenic Animals By Somatic Cell Nuclear Transfer

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US Patent:
20040025193, Feb 5, 2004
Filed:
Jul 14, 2003
Appl. No.:
10/619055
Inventors:
Yann Echelard - Jamaica Plain MA, US
International Classification:
A01K067/027
US Classification:
800/006000, 800/018000, 800/021000
Abstract:
The present invention provides for the production of homozygous primary cells that carry a specific transgenic integration of interest on both chromosomes by bypassing breeding. These cell lines can they be used for the accelerated production of homozygous transgenic animals by somatic cell nuclear transfer. The invention is thus useful in the production of transgenic ungulate animals capable of producing desired biopharmaceuticals in their milk at higher yield than a comparable heterzygote. By combining the selection techniques of the current invention with somatic cell nuclear transfer it can be applied to large animals, where there is a strong need to shorten the time to homozygosity.

Transgenically Produced Fusion Proteins

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US Patent:
20040117863, Jun 17, 2004
Filed:
Jun 27, 2003
Appl. No.:
10/608710
Inventors:
Michael Edge - Macclesfield, GB
Dan Pollock - Medway MA, US
Yann Echelard - Jamaica Plain MA, US
Harry Meade - Newton MA, US
Susanna Rybak - Frederick MD, US
International Classification:
A01K067/027
US Classification:
800/007000
Abstract:
A method of making a transgenic fusion protein. The method inlcudes providing a transgenic animal which includes a transgene which provides for the expression of the fusion protein; allowing the transgene to be expressed; and, recovering the fusion protein, from the milk of the transgenic animal.

Method And System For Utilizing Somatic Cell Nuclear Transfer Embryos As Cell Donors For Additional Nuclear Transfer

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US Patent:
20040148648, Jul 29, 2004
Filed:
Dec 9, 2003
Appl. No.:
10/731542
Inventors:
Esmail Behboodi - Worcester MA, US
Erdogan Memili - Shrewsbury MA, US
Yann Echelard - Jamaica Plain MA, US
International Classification:
A01K067/027
US Classification:
800/014000, 800/021000
Abstract:
The present invention provides method to improve the efficiency of both serial nuclear transfer and the consequent production of transgenic cells and/or animals. This new method, through the use of at least a second round of nuclear transfer, will enable donor cells to correct their reprogramming more efficiently generating larger numbers of useful transgenic embryos. Because the reprogramming of the embryos generated is enhanced the current invention will allow for the production of healthier transgenic animals.

Method Of Using Recombinant Human Antithrombin For Neurocognitive Disorders

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US Patent:
20050245444, Nov 3, 2005
Filed:
Apr 30, 2004
Appl. No.:
10/835836
Inventors:
Yann Echelard - Jamaica Plain MA, US
Harry Meade - Newton MA, US
International Classification:
C12Q001/68
A61K038/54
A01K067/027
US Classification:
514012000, 800006000, 800014000
Abstract:
The present invention provides for the production of recombinant human antithrombin (rhAT) for the treatment or prophylaxis of neurocognitive disorders typically associated with major surgical procedures. The recombinant processes of the current invention as well as more efficient methods of treatment, formulation and production have been developed to treat the incidence of neurocognitive problems associated with visuoconstruction, parieto-occipital watershed area injury, hypoperfusion, microemboli or other larger embolic factors and/or CABG procedures secondary to surgery.

Transgenically Produced Fusion Proteins

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US Patent:
20060026695, Feb 2, 2006
Filed:
Jun 24, 2005
Appl. No.:
11/166994
Inventors:
Michael Edge - Macclesfield, GB
Dan Pollock - Medway MA, US
Yann Echelard - Jamaica Plain MA, US
Harry Meade - Newton MA, US
Susanna Rybak - Frederick MD, US
International Classification:
A01K 67/027
C12P 21/06
US Classification:
800004000, 435069100
Abstract:
A method of making a transgenic fusion protein. The method inlcudes providing a transgenic animal which includes a transgene which provides for the expression of the fusion protein; allowing the transgene to be expressed; and, recovering the fusion protein, from the milk of the transgenic animal.

Methods Of Reducing The Incidence Of Rejection In Tissue Transplantation Through The Use Of Recombinant Human Antithrombin

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US Patent:
20060121004, Jun 8, 2006
Filed:
Dec 7, 2004
Appl. No.:
11/006055
Inventors:
Yann Echelard - Jamaica Plain MA, US
Francois Pattou - Lille, FR
Merce Jourdain - Lille, FR
International Classification:
A61K 35/12
A61K 38/48
US Classification:
424093700
Abstract:
The use of antithrombin to improve the therapeutic efficacy of cell and organ transplantation.
Yann Echelard from Jamaica Plain, MA, age ~61 Get Report