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Yanbin Lao

from Alpharetta, GA
Age ~49
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Also known as:
Yan Lao, Yan-Bin Lao, Bin Lao Yan, Lao Yanbin, Fei Jie
Related to:
Xinghua Yang, 61Jun Yan, 52
Connected to:
Andy K Lao, 61Asa K Lao, 36Bryan A Lao, 37Danielle M Lao, 34Darlene E Lao, 56Diana Lao, 34Edgar I Lao, 49Eladio M Lao, 84Erick T Lao, 53Fiona Lao, 33

Yanbin Lao Phones & Addresses

  • Alpharetta, GA
  • Zionsville, IN
  • Chicago, IL
  • 29578 Birch Ave, Lake Bluff, IL 60044 (847) 234-6993
  • 772 Darnell Ln, Gurnee, IL 60031
  • Maple Grove, MN
  • Minneapolis, MN
  • Richmond, KY
  • Lane, IL
  • Saint Paul, MN

Work

Company: Eli lilly and company 2016 Position: Principal research scientist

Education

Degree: Doctorates, Doctor of Philosophy School / High School: University of Minnesota 2001 to 2006 Specialities: Chemistry

Skills

Analytical Chemistry • Drug Metabolism • Program Management • Drug Design • Hplc • Drug Development • Mass Spectrometry • Bioanalysis • Adme • Lc Ms • Pharmacokinetics • Dmpk • Drug Discovery

Industries

Pharmaceuticals

Resumes

Resumes

Yanbin Lao Photo 1

Principal Research Scientist

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Location:
7043 Fox Hollow Rdg, Zionsville, IN 46077
Industry:
Pharmaceuticals
Work:
Eli Lilly and Company
Principal Research Scientist
Abbvie 2013 - 2016
Senior Scientist Iii
Abbott Jul 2009 - Jan 2013
Senior Scientist Ii
Abbott Dec 2006 - Jun 2009
Senior Scientist I
Education:
University of Minnesota 2001 - 2006
Doctorates, Doctor of Philosophy, Chemistry Peking University 1998 - 2001
Master of Science, Masters, Chemistry East China University of Science and Technology
Skills:
Analytical Chemistry
Drug Metabolism
Program Management
Drug Design
Hplc
Drug Development
Mass Spectrometry
Bioanalysis
Adme
Lc Ms
Pharmacokinetics
Dmpk
Drug Discovery

Publications

Us Patents

N-Phenyl-(Piperazinyl Or Homopiperazinyl)-Benzenesulfonamide Or Benzenesulfonyl-Phenyl-(Piperazine Or Homopiperazine) Compounds Suitable For Treating Disorders That Respond To Modulation Of The Serotonin 5-Ht6 Receptor

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US Patent:
8343959, Jan 1, 2013
Filed:
Oct 28, 2011
Appl. No.:
13/284204
Inventors:
Andreas Haupt - Ludwigshafen, DE
Frauke Pohlki - Ludwigshafen, DE
Karla Drescher - Ludwigshafen, DE
Karsten Wicke - Ludwigshafen, DE
Liliane Unger - Ludwigshafen, DE
Ana-Lucia Relo - Ludwigshafen, DE
Anton Bespalov - Ludwigshafen, DE
Barbara Vogg - Ludwigshafen, DE
Gisela Backfisch - Ludwigshafen, DE
Juergen Delzer - Ludwigshafen, DE
Min Zhang - Abbott Park IL, US
Yanbin Lao - Abbott Park IL, US
Assignee:
Abbott GmbH & Co. KG - Wiesbaden
Abbott Laboratories - Abbott Park IL
International Classification:
A61K 31/495
A61K 31/496
A61K 31/551
C07D 295/112
C07D 317/64
C07D 317/66
US Classification:
514218, 51425411, 51425503, 540575, 544377, 544395
Abstract:
The present invention relates to N-phenyl-(piperazinyl or homopiperazinyl)-benzenesulfonamide or benzenesulfonyl-phenyl-(piperazine or homopiperazine) compounds, pharmaceutical compositions containing them, and their use in therapy. The compounds possess valuable therapeutic properties and are particularly suitable for treating diseases that respond to modulation of the serotonin 5-HTreceptor.

Carboxamide Compounds And Their Use As Calpain Inhibitors Iv

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US Patent:
8598211, Dec 3, 2013
Filed:
Dec 20, 2010
Appl. No.:
12/972679
Inventors:
Andreas Kling - Ludwigshafen, DE
Katja Jantos - Ludwigshafen, DE
Helmut Mack - Ludwigshafen, DE
Achim Möller - Ludwigshafen, DE
Wilfried Hornberger - Ludwigshafen, DE
Gisela Backfisch - Ludwigshafen, DE
Yanbin Lao - Abbott Park IL, US
Assignee:
AbbVie Inc. - North Chicago IL
AbbVie Deutschland GmbH & Co. KG - Wiesbaden
International Classification:
A61K 31/4439
C07D 401/04
US Classification:
514341, 5462754, 5462761
Abstract:
The present invention relates to novel carboxamide compounds and their use for the manufacture of a medicament. The carboxamide compounds are inhibitors of calpain (calcium dependant cysteine proteases). The invention therefore also relates to the use of these carboxamide compounds for treating a disorder associated with an elevated calpain activity. The carboxamide compounds are compounds of the general formula I.

N-Phenyl- (Piperazinyl Or Homopiperazinyl)-Benzenesulfonamide Or Benzenesulfonyl-Phenl-(Piperazine Or Homopiperazine) Compounds Suitable For Treating Disorders That Respond To Modulation Of The Serotonin 5-Ht6 Receptor

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US Patent:
20100280014, Nov 4, 2010
Filed:
Apr 30, 2010
Appl. No.:
12/770837
Inventors:
Andreas Haupt - Ludwigshafen, DE
Frauke Pohlki - Ludwigshafen, DE
Karla Drescher - Ludwigshafen, DE
Karsten Wicke - Ludwigshafen, DE
Liliane Unger - Ludwigshafen, DE
Ana-Lucia Relo - Ludwigshafen, DE
Anton Bespalov - Ludwigshafen, DE
Barbara Vogg - Ludwigshafen, DE
Gisela Backfisch - Ludwigshafen, DE
Juergen Delzer - Ludwigshafen, DE
Min Zhang - Abbott Park IL, US
Yanbin Lao - Abbott Park IL, US
Assignee:
Abbott GmbH & Co. KG - Wiesbaden
Abbott Laboratories - Abbott Park IL
International Classification:
A61K 31/551
C07D 295/135
C07D 243/08
C07D 405/12
A61K 31/495
A61P 25/28
A61P 25/18
A61P 3/04
A61P 25/30
A61K 31/496
US Classification:
514218, 544398, 540575, 544377, 51425503, 51425411
Abstract:
The present invention relates to N-phenyl-(piperazinyl or homopiperazinyl)-benzenesulfonamide or benzenesulfonyl-phenyl-(piperazine or homopiperazine) compounds, pharmaceutical compositions containing them, and their use in therapy. The compounds possess valuable therapeutic properties and are particularly suitable for treating diseases that respond to modulation of the serotonin 5-HTreceptor.

Carboxamide Compounds And Their Use As Calpain Inhibitors V

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US Patent:
20110152265, Jun 23, 2011
Filed:
Dec 20, 2010
Appl. No.:
12/972663
Inventors:
Andreas Kling - Ludwigshafen, DE
Katja Jantos - Ludwigshafen, DE
Helmut Mack - Ludwigshafen, DE
Achim Möller - Ludwigshafen, DE
Wilfried Hornberger - Ludwigshafen, DE
Gisela Backfisch - Ludwigshafen, DE
Yanbin Lao - Abbott Park IL, US
Assignee:
Abbott GmbH & Co. KG - Wiesbaden
Abbott Laboratories - Abbott Park IL
International Classification:
A61K 31/5355
C07D 401/04
A61K 31/4439
A61P 25/28
A61P 25/16
A61P 25/08
A61P 9/00
A61P 13/12
A61P 31/18
A61P 33/06
C07D 413/14
US Classification:
5142365, 5462754, 514341, 544131
Abstract:
The present invention relates to novel carboxamide compounds and their use for the manufacture of a medicament. The carboxamide compounds are inhibitors of calpain (calcium dependant cysteine proteases). The invention therefore also relates to the use of these carboxamide compounds for treating a disorder associated with an elevated calpain activity.The carboxamide compounds are compounds of the general formula Iin which R, R, RR, R, m and n have the meanings mentioned in the claims and the description, the tautomers thereof, the hydrates thereof and the pharmaceutically suitable salts thereof. Of these compounds those are preferred wherein Ris optionally substituted phenyl-C-C-alkyl or hetaryl-C-C-alkyl, Ris optionally substituted aryl, hetaryl, aryl-C-C-alkyl, aryl-C-C-alkenyl or hetaryl-C-C-alkyl, Ris C-C-alkyl, C-C-haloalkyl, C-C-alkenyl, C-C-cycloalkyl, C-C-cycloalkyl-C-C-alkyl, or phenyl-C-C-alkyl, Rand Rindependently of one another are halogen, CF, CHF, CHF, C-C-alkyl or C-C-alkoxy, and m and n independently of one another are 0 or 1.

N-Phenyl-(Piperazinyl Or Homopiperazinyl)-Benzenesulfonamide Or Benzenesulfonyl-Phenyl-(Piperazine Or Homopiperazine) Compounds Suitable For Treating Disorders That Respond To Modulation Of The Serotonin 5-Ht6 Receptor

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US Patent:
20130018047, Jan 17, 2013
Filed:
Sep 14, 2012
Appl. No.:
13/618865
Inventors:
Andreas Haupt - Ludwigshafen, DE
Frauke Pohlki - Ludwigshafen, DE
Karla Drescher - Ludwigshafen, DE
Karsten Wicke - Ludwigshafen, DE
Liliane Unger - Ludwigshafen, DE
Ana-Lucia Relo - Ludwigshafen, DE
Anton Bespalov - Ludwigshafen, DE
Barbara Vogg - Ludwigshafen, DE
Gisela Backfisch - Ludwigshafen, DE
Juergen Delzer - Ludwigshafen, DE
Min Zhang - Abbott Park IL, US
Yanbin Lao - Abbott Park IL, US
Assignee:
Abbott Laboratories - Abbott Park IL
Abbott GmbH & Co. KG - Wiesbaden
International Classification:
A61K 31/495
A61K 31/496
A61P 25/30
A61K 31/551
US Classification:
514218, 51425503, 51425411
Abstract:
The present invention relates to N-phenyl-(piperazinyl or homopiperazinyl)-benzenesulfonamide or benzenesulfonyl-phenyl-(piperazine or homopiperazine) compounds, pharmaceutical compositions containing them, and their use in therapy. The compounds possess valuable therapeutic properties and are particularly suitable for treating diseases that respond to modulation of the serotonin 5-HTreceptor.

Carboxamide Compounds And Their Use As Calpain Inhibitors V

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US Patent:
20140005227, Jan 2, 2014
Filed:
Dec 8, 2011
Appl. No.:
13/992582
Inventors:
Andreas Kling - Ludwigshafen, DE
Katja Jantos - Ludwigshafen, DE
Helmut Mack - Ludwigshafen, DE
Achim Moller - Wiesbaden, DE
Wilfried Hornberger - Ludwigshafen, DE
Yanbin Lao - North Chicago IL, US
Gisela Backfisch - Ludwigshafen, DE
Assignee:
ABBVIE Deutschland GmbH & Co. KG - Wiesbaden
International Classification:
C07D 401/04
US Classification:
514338, 5462757
Abstract:
The present invention relates to novel carboxamide compounds and their use for the manufacture of a medicament. The carboxamide compounds are inhibitors of calpain (calcium dependant cysteine proteases). The invention therefore also relates to the use of these carboxamide compounds for treating a disorder associated with an elevated calpain activity. The carboxamide compounds are compounds of the general formula (I) in which R, R, R, R, X, m and n have the meanings mentioned in the claims and the description, the tautomers thereof, the hydrates thereof and the pharmaceutically suitable salts thereof. Of these compounds those are preferred wherein Ris optionally substituted benzyl or hetaryl-methyl, X is a single bond or an oxygen atom, Ris C-C-alkyl, C-C-haloalkyl, C-C-alkenyl, C-C-cycloalkyl, C-C-cycloalkyl-C-C-alkyl, C-C-heterocycloalkyl-C-C-alkyl, phenyl, phenyl-C-C-alkyl, pyridin-2-yl-C-C-alkyl or CH—C(O)OCH, Rand Rindependently of one another are halogen, CN, CF, CHF, CHF, C-C-alkyl or C-C-alkoxy, and m and n independently of one another are 0 or 1.

Methods Of Treating Parkinson's Disease

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US Patent:
20230106081, Apr 6, 2023
Filed:
Oct 24, 2022
Appl. No.:
17/971836
Inventors:
- North Chicago IL, US
Vincent S. Chan - Evanston IL, US
Kassibla E. Dempah - Chicago IL, US
Brian P. Enright - Gurnee IL, US
Rodger F. Henry - Wildwood IL, US
Raimundo Ho - Chicago IL, US
Ye Huang - Gurnee IL, US
Alexander D. Huters - Chicago IL, US
Russell C. Klix - Buffalo Grove IL, US
Scott W. Krabbe - Lindenhurst IL, US
Philip R. Kym - Libertyville IL, US
Yanbin Lao - Lake Bluff IL, US
Xiaochun Lou - Long Grove IL, US
Sean E. Mackey - Grayslake IL, US
Mark A. Matulenko - Libertyville IL, US
Peter T. Mayer - Libertyville IL, US
Christopher P. Miller - Lake Forest IL, US
James Stambuli - Worcester MA, US
Valentino J. Stella - Lawrence KS, US
Eric A. Voight - Pleasant Prairie WI, US
Zhi Wang - Libertyville IL, US
Geoff G. Zhang - Vernon Hills IL, US
International Classification:
C07F 9/09
A61K 31/661
C07F 9/06
C07C 281/02
C07C 309/24
C07C 47/277
A61K 31/6615
A61K 45/06
Abstract:
The present disclosure relates to (a) carbidopa prodrugs, (b) pharmaceutical combinations and compositions comprising a carbidopa prodrug and/or an L-dopa prodrug, and (c) methods of treating Parkinson's disease and associated conditions comprising administering a carbidopa prodrug and an L-dopa prodrug to a subject with Parkinson's disease.

Carbidopa Prodrugs

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US Patent:
20200262852, Aug 20, 2020
Filed:
May 4, 2020
Appl. No.:
16/866400
Inventors:
- North Chicago IL, US
Vincent S. Chan - Evanston IL, US
Kassibla E. Dempah - Chicago IL, US
Brian P. Enright - Gumee IL, US
Rodger F. Henry - Wildwood IL, US
Raimundo Ho - Chicago IL, US
Ye Huang - Gumee IL, US
Alexander D. Huters - Chicago IL, US
Russell C. Klix - Buffalo Grove IL, US
Scott W. Krabbe - Lindenhurst IL, US
Philip R. Kym - Libertyville IL, US
Yanbin Lao - Lake Bluff IL, US
Xiaochun Lou - Long Grove IL, US
Sean E. Mackey - Grayslake IL, US
Mark A. Matulenko - Libertyville IL, US
Peter T. Mayer - Libertyville IL, US
Christopher P. Miller - Lake Forest IL, US
James Stambuli - Buffalo Grove IL, US
Valentino J. Stella - Lawrence KS, US
Eric A. Voight - Pleasant Prairie WI, US
Zhi Wang - Libertyville IL, US
Geoff Zhang - Vernon Hills IL, US
International Classification:
C07F 9/09
A61K 45/06
A61K 31/6615
C07C 47/277
C07C 309/24
C07C 281/02
C07F 9/06
A61K 31/661
Abstract:
The present disclosure relates to (a) carbidopa prodrugs, (b) pharmaceutical combinations and compositions comprising a carbidopa prodrug and/or an L-dopa prodrug, and (c) methods of treating Parkinson's disease and associated conditions comprising administering a carbidopa prodrug and an L-dopa prodrug to a subject with Parkinson's disease.
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Yanbin Lao from Alpharetta, GA, age ~49 Get Report