Inventors:
Yaguang Liu - Flushing NY, 11365
International Classification:
A61K 3578
US Classification:
514295, 424725, 514290, 514423, 514425, 546 98, 548530, 548539, 548543, 548544, 548555
Abstract:
The present invention related to safe botanical drug for treatment and prevention of Alzheimers disease. Specifically, this invention proves a safe botanical drug, Huperzine (HUE) and Clausenamide (CLE) and their preparation. HUE has the following pharmaceutical functions: inhibiting acetylcholinesterase (CAT), increasing memory, decreasing Alzheimer amyloid protein, increasing RNA and protein synthesis of brain, increasing calcium in brain, decreasing superoxide anion. CLE has the following pharmaceutical functions: increasing memory, decreasing Alzheimer amyloid protein, increasing RNA and protein synthesis of brain, increasing calcium in brain, decreasing superoxide anion, increasing long-term potentiation and increasing dopanmine (DA). It is important that HUE combined with CLE have stronger function as mentioned above.