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Yafan Lu

from Foster City, CA
Age ~60
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Also known as:
Yafan Yu, Lu Yafan
Related to:
Chi Chang LiuFang H Yu, 63Jennie H Lu, 53Li HuangWei H Liao, 59
Connected to:
Aiyan Lu, 33Alisha Lu, 36Anita Lu, 42Anne C Lu, 85Audriana Lu, 35Bob H Lu, 64Bochao Lu, 34Bowen K Lu, 31Bryant D Lu, 69Cante V Lu, 60

Yafan Lu Phones & Addresses

  • Foster City, CA
  • South San Francisco, CA
  • San Francisco, CA
  • Louisville, KY

Publications

Us Patents

Compounds For The Treatment Of Addiction

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US Patent:
8558001, Oct 15, 2013
Filed:
Jun 29, 2012
Appl. No.:
13/537536
Inventors:
Carina E. Cannizzaro - Foster City CA, US
Michael Graupe - Pacifica CA, US
Juan A. Guerrero - Concord CA, US
Yafan Lu - Foster City CA, US
Robert G. Strickley - San Mateo CA, US
Chandrasekar Venkataramani - Redwood City CA, US
Jeff Zablocki - Los Altos CA, US
Assignee:
Gilead Sciences, Inc. - Foster City CA
International Classification:
C07D 213/62
A61K 31/44
US Classification:
546300, 514351
Abstract:
Disclosed are novel compounds having the structure of Formula (I):.

Compounds For The Treatment Of Addiction

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US Patent:
8575353, Nov 5, 2013
Filed:
Mar 8, 2013
Appl. No.:
13/791422
Inventors:
Michael Graupe - Pacifica CA, US
Juan A. Guerrero - Concord CA, US
Yafan Lu - Foster City CA, US
Robert G. Strickley - San Mateo CA, US
Chandrasekar Venkataramani - Redwood City CA, US
Jeff Zablocki - Los Altos CA, US
Assignee:
Gilead Sciences, Inc. - Foster City CA
International Classification:
C07D 213/62
A61K 31/47
US Classification:
546300, 514314
Abstract:
Disclosed are novel compounds having the structure of Formula (I):.

Aspartyl Protease Inhibitors

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US Patent:
20040132782, Jul 8, 2004
Filed:
Jun 16, 2003
Appl. No.:
10/462127
Inventors:
Wenjin Yang - Foster City CA, US
Douglas Cary - San Francisco CA, US
Jeffrey Jacobs - San Mateo CA, US
Wanli Lu - Burlingame CA, US
Yafan Lu - South San Francisco CA, US
Jian Sun - San Mateo CA, US
Min Zhong - Foster City CA, US
International Classification:
A61K031/44
A61K031/40
A61K031/165
A61K031/155
US Classification:
514/357000, 514/408000, 514/534000, 514/599000, 514/634000, 514/620000, 514/603000, 546/329000, 548/571000, 560/041000, 564/086000, 564/163000, 564/237000
Abstract:
The present invention provides compounds having formula (I): wherein R′, R, R, X, R, R, R, X, Xand Rare as defined herein, and pharmaceutical compositions thereof. The present invention also provides methods of inhibiting proteases, more specifically aspartyl proteases. In certain embodiments, compounds inhibit BACE (-site APP-cleaving enzyme), and thus are useful in the treatment or prevention of a disease characterized by -amyloid deposits in the brain (including, but not limited to, Alzheimer's Disease). The present invention also provides methods for preparing compounds of the invention.

Compounds For The Treatment Of Addiction

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US Patent:
20140051668, Feb 20, 2014
Filed:
Aug 13, 2013
Appl. No.:
13/966029
Inventors:
Michael Graupe - Pacifica CA, US
Juan A. Guerrero - Concord CA, US
Yafan Lu - Foster City CA, US
Robert G. Strickley - San Mateo CA, US
Chandrasekar Venkataramani - Redwood City CA, US
Jeff Zablocki - Los Altos CA, US
Assignee:
Gilead Sciences, Inc. - Foster City CA
International Classification:
C07F 9/58
C07D 213/64
US Classification:
514 89, 514351
Abstract:
Disclosed are novel compounds having the structure of Formula (I):which are useful for treating mammals for dependence upon substances of addiction, for example addiction to a dopamine-producing agent such as cocaine, morphine, amphetamines, nicotine, and/or alcohol. Also disclosed are pharmaceutical compositions comprising a therapeutically effective amount of a compound of Formula (I) and methods of using the compounds of Formula (I) in the treatment of addiction to a dopamine-producing agent.

Therapeutic Compounds

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US Patent:
20210009555, Jan 14, 2021
Filed:
May 26, 2020
Appl. No.:
16/882804
Inventors:
- Foster City CA, US
Eda Canales - San Mateo CA, US
Chien-Hung Chou - Dublin CA, US
Michael Graupe - Pacifica CA, US
Randall L. Halcomb - Foster City CA, US
Yunfeng Eric Hu - San Mateo CA, US
Scott E. Lazerwith - Burlingame CA, US
John O. Link - San Francisco CA, US
Qi Liu - Union City CA, US
Yafan Lu - Foster City CA, US
Roland D. Saito - San Mateo CA, US
Scott D. Schroeder - Union City CA, US
John R. Somoza - Foster City CA, US
Winston C. Tse - Redwood City CA, US
Jennifer R. Zhang - Union City CA, US
International Classification:
C07D 401/12
C07D 401/14
C07D 403/14
C07D 471/04
A61K 31/437
A61K 31/4439
A61K 31/444
A61K 31/4725
A61K 31/496
A61K 31/506
A61K 31/517
A61K 31/5377
A61K 45/06
C07D 491/052
C07D 401/04
C07D 413/14
C07D 417/14
C07D 487/04
Abstract:
Compounds of formula (I) or salts thereof are disclosed. Also disclosed are pharmaceutical compositions comprising a compound of formula I, processes for preparing compounds of formula I, intermediates useful for preparing compounds of formula I and therapeutic methods for treating a Retroviridae viral infection including an infection caused by the HIV virus.

Compounds For The Treatment Of Addiction

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US Patent:
20180338989, Nov 29, 2018
Filed:
May 8, 2018
Appl. No.:
15/974171
Inventors:
- Palo Alto CA, US
Michael Graupe - Pacifica CA, US
Juan A. Guerrero - Concord CA, US
Yafan Lu - Foster City CA, US
Robert G Strickley - San Mateo CA, US
Chandrasekar Venkataramani - Redwood City CA, US
Jeff Zablocki - Los Altos CA, US
Assignee:
Amygdala Neurosciences, Inc. - Palo Alto CA
International Classification:
A61K 31/675
C07F 9/58
C07D 213/64
A61K 31/4418
Abstract:
Disclosed are novel compounds having the structure of Formula (I):which are useful for treating mammals for dependence upon substances of addiction, for example addiction to a dopamine-producing agent such as cocaine, morphine, amphetamines, nicotine, and/or alcohol. Also disclosed are pharmaceutical compositions comprising a therapeutically effective amount of a compound of Formula (I) and methods of using the compounds of Formula (I) in the treatment of addiction to a dopamine-producing agent.

Therapeutic Compounds

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US Patent:
20180273508, Sep 27, 2018
Filed:
Mar 2, 2018
Appl. No.:
15/910083
Inventors:
- Foster City CA, US
Eda Canales - San Mateo CA, US
Chien-Hung Chou - Dublin CA, US
Michael Graupe - Pacifica CA, US
Randall L. Halcomb - Foster City CA, US
Yunfeng Eric Hu - San Mateo CA, US
Scott E. Lazerwith - Burlingame CA, US
John O. Link - San Francisco CA, US
Qi Liu - Union City CA, US
Yafan Lu - Foster City CA, US
Roland D. Saito - San Mateo CA, US
Scott D. Schroeder - Union City CA, US
John R. Somoza - Foster City CA, US
Winston C. Tse - Redwood City CA, US
Jennifer R. Zhang - Union City CA, US
International Classification:
C07D 401/12
C07D 487/04
A61K 31/517
A61K 31/496
A61K 31/4725
C07D 491/052
A61K 31/4439
A61K 31/437
A61K 45/06
A61K 31/444
A61K 31/5377
C07D 401/14
C07D 403/14
C07D 471/04
C07D 401/04
C07D 417/14
C07D 413/14
A61K 31/506
Abstract:
Compounds of formula (I) or salts thereof are disclosed. Also disclosed are pharmaceutical compositions comprising a compound of formula I, processes for preparing compounds of formula I, intermediates useful for preparing compounds of formula I and therapeutic methods for treating a Retroviridae viral infection including an infection caused by the HIV virus.

Compounds For The Treatment Of Addiction

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US Patent:
20170266210, Sep 21, 2017
Filed:
Mar 31, 2017
Appl. No.:
15/476569
Inventors:
- Palo Alto CA, US
Michael Graupe - Pacifica CA, US
Juan A. Guerrero - Concord CA, US
Yafan Lu - Foster City CA, US
Robert G. Strickley - San Mateo CA, US
Chandrasekar Venkataramani - Redwood City CA, US
Jeff Zablocki - Los Altos CA, US
Assignee:
Amygdala Neurosciences, Inc. - Palo Alto CA
International Classification:
A61K 31/675
A61K 31/4418
C07D 213/64
C07F 9/58
Abstract:
Disclosed are novel compounds having the structure of Formula (I):which are useful for treating mammals for dependence upon substances of addiction, for example addiction to a dopamine-producing agent such as cocaine, morphine, amphetamines, nicotine, and/or alcohol. Also disclosed are pharmaceutical compositions comprising a therapeutically effective amount of a compound of Formula (I) and methods of using the compounds of Formula (I) in the treatment of addiction to a dopamine-producing agent.
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Yafan Lu from Foster City, CA, age ~60 Get Report