Resumes
Resumes
Xiaojie Zhu Phones & Addresses
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12 Linda Rd, Andover, MA 01810 (978) 475-9380
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7 Crescent Dr, Andover, MA 01810 (978) 475-9380
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Arlington, TX
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Burlington, MA
Publications
Us Patents
Intermediates And Methods For Making Zearalenone Macrolide Analogs
View pageUS Patent:
8350059, Jan 8, 2013
Filed:
Dec 8, 2008
Appl. No.:
12/746672
Inventors:
Roch Boivin - North Chelmsford MA, US
Silvio A. Campagna - Candia NH, US
Hong Du - North Andover MA, US
Francis G. Fang - Andover MA, US
Thomas Horstmann - Boston MA, US
Charles-Andre Lemelin - North Chelmsford MA, US
Jing Li - College Station TX, US
Pamela McGuinness - Methuen MA, US
Xiang Niu - Watertown MA, US
Matthew J. Schnaderbeck - Methuen MA, US
Kevin (kuo-ming) Wu - Acton MA, US
Xiaojie (jeff) Zhu - Andover MA, US
Silvio A. Campagna - Candia NH, US
Hong Du - North Andover MA, US
Francis G. Fang - Andover MA, US
Thomas Horstmann - Boston MA, US
Charles-Andre Lemelin - North Chelmsford MA, US
Jing Li - College Station TX, US
Pamela McGuinness - Methuen MA, US
Xiang Niu - Watertown MA, US
Matthew J. Schnaderbeck - Methuen MA, US
Kevin (kuo-ming) Wu - Acton MA, US
Xiaojie (jeff) Zhu - Andover MA, US
Assignee:
Eisai R&D Management Co., Ltd. - Tokyo
International Classification:
C07D 493/00
US Classification:
549270
Abstract:
Disclosed herein are methods and intermediates useful in the preparation of macrolides, e. g. , compounds of formula (IV) wherein R-Rare as defined herein.
Luminacin Analogs And Uses Thereof
View pageUS Patent:
20050228039, Oct 13, 2005
Filed:
Dec 18, 2002
Appl. No.:
10/500424
Inventors:
Francis Fang - ANDOVER MA, US
Charles Johannes - Newbury MA, US
Ye Yao - North Andover MA, US
Xiaojie Zhu - Andover MA, US
Charles Johannes - Newbury MA, US
Ye Yao - North Andover MA, US
Xiaojie Zhu - Andover MA, US
International Classification:
A61K031/353
C07D305/14
C07D493/04
C07D305/14
C07D493/04
US Classification:
514456000, 514459000, 549332000
Abstract:
The present invention provides compounds having formula (I) (and pharmaceutically acceptable derivatives thereof): and additionally provides methods for the synthesis thereof and methods for the use thereof in the treatment of cancer, wherein R-Rand n are as defined herein.
Luminacin Analogs And Uses Thereof
View pageUS Patent:
20080249320, Oct 9, 2008
Filed:
Apr 9, 2008
Appl. No.:
12/100194
Inventors:
Francis Fang - Andover MA, US
Charles Johannes - Newbury MA, US
Ye Yao - North Andover MA, US
Xiaojie (Jeff) Zhu - Andover MA, US
Charles Johannes - Newbury MA, US
Ye Yao - North Andover MA, US
Xiaojie (Jeff) Zhu - Andover MA, US
International Classification:
C07D 493/10
US Classification:
549332
Abstract:
The present invention provides compounds having formula (I) (and pharmaceutically acceptable derivatives thereof):and additionally provides methods for the synthesis thereof and methods for the use thereof in the treatment of cancer, wherein R-Rand n are as defined herein.
Intermediates For The Preparation Of Analogs Of Halichondrin B
View pageUS Patent:
20120029213, Feb 2, 2012
Filed:
Jun 29, 2011
Appl. No.:
13/171971
Inventors:
Brian Austad - Tewksbury MA, US
Farid Benayoud - North Andover MA, US
Trevor Calkins - Stoughton WI, US
Silvio Campagna - Candia NH, US
Charles E. Chase - Londonderry NH, US
William Christ - Andover MA, US
Francis G. Fang - Andover MA, US
Yongbo Hu - Westborough MA, US
Bryan M. Lewis - North Brunswick NJ, US
Marc Pesant - Saint-Colomban, CA
Matthew Schnaderbeck - Methuen MA, US
Gordon Wilkie - North Andover MA, US
Xiaojie Zhu - Andover MA, US
Farid Benayoud - North Andover MA, US
Trevor Calkins - Stoughton WI, US
Silvio Campagna - Candia NH, US
Charles E. Chase - Londonderry NH, US
William Christ - Andover MA, US
Francis G. Fang - Andover MA, US
Yongbo Hu - Westborough MA, US
Bryan M. Lewis - North Brunswick NJ, US
Marc Pesant - Saint-Colomban, CA
Matthew Schnaderbeck - Methuen MA, US
Gordon Wilkie - North Andover MA, US
Xiaojie Zhu - Andover MA, US
Assignee:
Eisai R&D Management Co., Ltd. - Tokyo
International Classification:
C07D 407/14
C07D 493/20
C07D 493/10
C07F 7/08
C07D 307/28
C07D 493/20
C07D 493/10
C07F 7/08
C07D 307/28
US Classification:
549214, 549348, 549501, 549337
Abstract:
Intermediates and methods of their use in the synthesis of analogs of halichondrin B are provided.
Intermediates And Methods For Making Zearalenone Macrolide Analogs
View pageUS Patent:
20130211103, Aug 15, 2013
Filed:
Jan 3, 2013
Appl. No.:
13/733562
Inventors:
EISAI R&D MANAGEMENT CO., LTD. - , US
Silvio A. Campagna - Candia NH, US
Hong Du - North Andover MA, US
Francis G. Fang - Andover MA, US
Thomas Horstmann - Boston MA, US
Charles-Andre Lemelin - North Chelmsford MA, US
Jing Li - College Station TX, US
Pamela McGuinness - Methuen MA, US
Xiang Niu - Watertown MA, US
Matthew J. Schnaderbeck - Methuen MA, US
Kevin (kuo-ming) Wu - Acton MA, US
Xiaojie (jeff) Zhu - Andover MA, US
Silvio A. Campagna - Candia NH, US
Hong Du - North Andover MA, US
Francis G. Fang - Andover MA, US
Thomas Horstmann - Boston MA, US
Charles-Andre Lemelin - North Chelmsford MA, US
Jing Li - College Station TX, US
Pamela McGuinness - Methuen MA, US
Xiang Niu - Watertown MA, US
Matthew J. Schnaderbeck - Methuen MA, US
Kevin (kuo-ming) Wu - Acton MA, US
Xiaojie (jeff) Zhu - Andover MA, US
Assignee:
EISAI R&D MANAGEMENT CO., LTD. - Tokyo
International Classification:
C07D 313/00
C07D 317/30
C07D 317/30
US Classification:
549270, 549451
Abstract:
Disclosed herein are methods and intermediates useful in the preparation of macrolides, e.g., compounds of formula (IV)wherein R-Rare as defined herein.
Ep4 Antagonists
View pageUS Patent:
20210347779, Nov 11, 2021
Filed:
Jan 5, 2021
Appl. No.:
17/141557
Inventors:
- Tokyo, JP
Xiaojie ZHU - Andover MA, US
Hong DU - Andover MA, US
Maarten POSTEMA - Dublin NH, US
Yimin JIANG - Londonderry NH, US
Jing LI - Andover MA, US
Robert YU - Arlington MA, US
Jaemoon LEE - Andover MA, US
Francis G. FANG - Andover MA, US
Daniel CUSTAR - North Andover MA, US
Xiaojie ZHU - Andover MA, US
Hong DU - Andover MA, US
Maarten POSTEMA - Dublin NH, US
Yimin JIANG - Londonderry NH, US
Jing LI - Andover MA, US
Robert YU - Arlington MA, US
Jaemoon LEE - Andover MA, US
Francis G. FANG - Andover MA, US
Daniel CUSTAR - North Andover MA, US
Assignee:
Eisai R&D Management Co., Ltd. - Tokyo
International Classification:
C07D 487/04
C07D 519/00
A61P 35/00
C07D 519/00
A61P 35/00
Abstract:
We provide compounds given by Formula I, which is shown in FIG. , or pharmaceutically acceptable salts thereof, as well as formulations thereof and methods of use of those compounds and formulations for treatment of cancer.
Ep4 Antagonists
View pageUS Patent:
20190315754, Oct 17, 2019
Filed:
Apr 23, 2019
Appl. No.:
16/391882
Inventors:
- Tokyo, JP
Xiaojie Zhu - Andover MA, US
Hong Du - North Andover MA, US
Maarten Postema - Dublin NH, US
Yimin Jiang - Londonderry NH, US
Jing Li - Andover MA, US
Robert Yu - Arlington MA, US
Jaemoon Lee - Andover MA, US
Frank Fang - Andover MA, US
Daniel Custar - North Andover MA, US
Xiaojie Zhu - Andover MA, US
Hong Du - North Andover MA, US
Maarten Postema - Dublin NH, US
Yimin Jiang - Londonderry NH, US
Jing Li - Andover MA, US
Robert Yu - Arlington MA, US
Jaemoon Lee - Andover MA, US
Frank Fang - Andover MA, US
Daniel Custar - North Andover MA, US
Assignee:
Eisai R&D Management Co., Ltd. - Tokyo
International Classification:
C07D 487/04
C07D 519/00
A61P 35/00
C07D 519/00
A61P 35/00
Abstract:
We provide compounds given by Formula I, which is shown in FIG. , or pharmaceutically acceptable salts thereof, as well as formulations thereof and methods of use of those compounds and formulations for treatment of cancer.
Ep4 Antagonists
View pageUS Patent:
20180305362, Oct 25, 2018
Filed:
Oct 14, 2016
Appl. No.:
15/768668
Inventors:
- Tokyo, JP
Xiaojie Zhu - Andover MA, US
Hong Du - North Andover MA, US
Maarten Postema - Dublin NH, US
Yimin Jiang - Londonderry NH, US
Jing Li - Andover MA, US
Robert Yu - Arlington MA, US
Jaemoon Lee - Andover MA, US
Frank Fang - Andover MA, US
Daniel Custar - North Andover MA, US
Xiaojie Zhu - Andover MA, US
Hong Du - North Andover MA, US
Maarten Postema - Dublin NH, US
Yimin Jiang - Londonderry NH, US
Jing Li - Andover MA, US
Robert Yu - Arlington MA, US
Jaemoon Lee - Andover MA, US
Frank Fang - Andover MA, US
Daniel Custar - North Andover MA, US
Assignee:
Eisai R&D Management Co., Ltd. - Tokyo
International Classification:
C07D 487/04
C07D 519/00
A61P 35/00
C07D 519/00
A61P 35/00
Abstract:
We provide compounds given by Formula I, which is shown in FIG. , or pharmaceutically acceptable salts thereof, as well as formulations thereof and methods of use of those compounds and formulations for treatment of cancer.