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Xianzhi Z Zhou

from Rockville, MD
Age ~56

Xianzhi Zhou Phones & Addresses

  • 66 Calabash Ct, Rockville, MD 20850 (301) 279-0638
  • 9930 Alta Springs Way, Rockville, MD 20850
  • 16612 Benton Taylor Dr, Chesterfield, MO 63005 (636) 536-0177
  • 857 Foxsprings Dr, Chesterfield, MO 63017 (636) 536-0177
  • 10340 Briar Hollow Dr, Saint Louis, MO 63146
  • Bronx, NY
  • North Potomac, MD
  • Decatur, GA

Work

Company: Gsk Oct 2016 Position: Head of bioassay and immunoassay, analytical development

Education

Degree: Doctorates, Doctor of Philosophy School / High School: Albert Einstein College of Medicine 2009 to 2010

Industries

Pharmaceuticals

Resumes

Resumes

Xianzhi Zhou Photo 1

Head Of Bioassay And Immunoassay, Analytical Development

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Location:
66 Calabash Ct, Rockville, MD 20850
Industry:
Pharmaceuticals
Work:
Gsk
Head of Bioassay and Immunoassay, Analytical Development

Novavax Jul 1, 2015 - Sep 2016
Associate Director, Immunoassay, Analytical Development

Medimmune 2010 - 2015
Senior Scientist, Bioassay

Pfizer 2000 - 2010
Senior Research Scientist, Bioassay

Novartis 1999 - 1999
Postdoc
Education:
Albert Einstein College of Medicine 2009 - 2010
Doctorates, Doctor of Philosophy
Albert Einstein College of Medicine 1995 - 2000
Albert Einstein College of Medicine 1995 - 1999
Doctorates, Doctor of Philosophy, Biochemistry
Albert Einstein College of Medicine 1988 - 1991
Doctorates, Doctor of Philosophy
Sun Yat - Sen University
Bachelors, Chemistry

Publications

Us Patents

Human Methionine Aminopeptidase Type 3

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US Patent:
20030203406, Oct 30, 2003
Filed:
Nov 19, 2002
Appl. No.:
10/299867
Inventors:
Carolyn Sympson - Ballwin MO, US
Rajeev Aurora - Glencoe MO, US
Stanton Dotson - Chesterfield MO, US
Ronald Frazier - Lake St. Louis MO, US
Cynthia Woods - St. Peters MO, US
Hamideh Zakeri - Chesterfield MO, US
Xianzhi Zhou - Chesterfield MO, US
International Classification:
G01N033/53
C07H021/04
C12N009/64
C12P021/02
C12N005/06
C07K016/40
US Classification:
435/007100, 435/069100, 435/226000, 435/320100, 435/325000, 530/388260, 536/023200
Abstract:
Methionine aminopeptidases catalyse the co-translational removal of amino terminal methionine residues from nascent polypeptide chains. A newly-discovered enzyme, designated methionine aminopeptidase type-3 (MetAP-3), has a substrate specificity which is similar to MetAP-1 and MetAP-2, although it is not inhibited by fumagillin, an irreversible inhibitor of MetAP-2. MetAP-3 also preferentially localizes to mitochondria, unlike MetAP-1 and MetAP-2, which accumulate in the cytoplasm. One embodiment of the present invention relates to human cDNAs encoding polypeptides comprising MetAP-3. Other embodiments of the invention relate to nucleic acid molecules derived from these cDNAs, including complements, homologues, and fragments thereof, and methods of using these nucleic acid molecules, to generate polypeptides and fragments thereof. Other embodiments of the invention relate to antibodies directed against polypeptides comprising MetAP-3, and methods to screen for compounds or compositions that preferentially or specifically effect the activity of polypeptides comprising MetAP-3.

Hair Cosmetic Compositions

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US Patent:
20220273551, Sep 1, 2022
Filed:
Feb 28, 2021
Appl. No.:
17/187819
Inventors:
- Paris, FR
Seyma ASLAN - Clifton NJ, US
XianZhi ZHOU - Millburn NJ, US
Rita CHOKSHI - Monroe Township NJ, US
International Classification:
A61K 8/891
A61K 8/34
A61K 8/37
A61K 8/86
A61K 8/60
A61K 8/81
A61K 8/892
A61K 8/92
A61K 8/06
A61K 8/73
A61Q 5/06
Abstract:
Aspects of the disclosure are directed to a hair cosmetic composition comprising: about 4 to about 32 wt. % of two or more polyols, such as about 1 wt. % or more of a glycol and about 2 wt. % or more of glycerin; about 0.5 to about 10 wt. % of a nonionic surfactant; about 2 to about 35 wt. % of a fatty ester; about 0.1 to about 7 wt. % of a film former; about 0.05 to about 10 wt. % of a silicone polymer; about 0.5 to about 12 wt. % of an oil; and water, wherein all weight percentages are based on the total weight of the hair cosmetic composition.

Hair Cosmetic Compositions

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US Patent:
20220273552, Sep 1, 2022
Filed:
Feb 28, 2021
Appl. No.:
17/187811
Inventors:
- Paris, FR
Seyma ASLAN - Clifton NJ, US
XianZhi ZHOU - Millburn NJ, US
Rita CHOKSHI - Monroe Township NJ, US
International Classification:
A61K 8/892
A61K 8/34
A61K 8/37
A61K 8/81
A61K 8/92
A61K 8/891
A61K 8/58
A61K 8/06
A61Q 5/06
Abstract:
Aspects of the disclosure are directed to a hair cosmetic composition comprising about 4 to about 32 wt. % of two or more polyols, such as about 1 wt. % or more of a glycol and about 2 wt. % or more of glycerin; about 0.5 to about 10 wt. % of a nonionic surfactant; about 2 to about 25 wt. % of a fatty ester; about 0.1 to about 7 wt. % of a film former; about 0.1 to about 5 wt. % of a thickening agent; about 0.5 to about 12 wt. % of an oil; and water, wherein all weight percentages are based on the total weight of the hair cosmetic composition.

Kits For Applying Cosmetic Compositions

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US Patent:
20200069038, Mar 5, 2020
Filed:
Aug 31, 2018
Appl. No.:
16/119777
Inventors:
- Paris, FR
Jody Ebanks - Bloomfield NJ, US
Kyoo Park - Leonia NJ, US
XianZhi Zhou - Millburn NJ, US
Kathryn Andrea Zuccarello - Franklin Park NJ, US
Christopher Pang - New York NY, US
Assignee:
L'ORÉAL - Paris
International Classification:
A46B 9/02
A61K 8/34
A61K 8/81
A61Q 1/10
Abstract:
Kits for applying cosmetic compositions to keratinous material, in particular to (1) applicators comprising a brush comprising a core having an outer surface and a longitudinal axis; a plurality of bristles protruding from the core and spaced apart along the longitudinal axis; and a high density zone that covers at least a portion of the outer surface of the core, the high density zone having a surface bristle density of up to 7 bristles per square millimeter of area of the outer surface of the core, and wherein the bristles have a length from about 0.6 mm to about 4 mm and (2) cosmetic compositions for application to hair, eyebrows and/or eyelashes having a viscosity of less than about 250 PaS when measured at a shear rate at 5 sare provided.

Cosmetic Compositions Containing Oxazoline Functionalized Polymers And Polyamine Compounds

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US Patent:
20200069555, Mar 5, 2020
Filed:
Aug 31, 2018
Appl. No.:
16/118717
Inventors:
- Paris, FR
Jim Singer - South Orange NJ, US
XianZhi Zhou - Millburn NJ, US
Jennifer Haghpanah - Newtown CT, US
Charles Shaw - Seattle WA, US
Assignee:
L'OREAL - Paris
International Classification:
A61K 8/81
A61K 8/41
A61Q 5/12
A61Q 5/00
Abstract:
Disclosed are compositions, systems and methods for treating keratinous fibers such as hair. The compositions and systems comprise an oxazoline functionalized polymer and a polyamine compound. The compositions and methods are employed to improve the quality of the keratinous fibers.

Cosmetic Compositions Containing Oxazoline Functionalized Polymers And Amino Silicone Compounds

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US Patent:
20200069556, Mar 5, 2020
Filed:
Aug 31, 2018
Appl. No.:
16/118768
Inventors:
- Paris, FR
Jim SINGER - South Orange NJ, US
XianZhi ZHOU - Millburn NJ, US
Jennifer HAGHPANAH - Newtown CT, US
Charles SHAW - Seatlle WA, US
Assignee:
L'OREAL - Paris
International Classification:
A61K 8/898
A61Q 5/12
A61Q 5/00
A61K 8/81
Abstract:
Disclosed are compositions, systems and methods for treating keratinous fibers such as hair. The compositions and systems comprise an oxazoline functionalized polymer and an amino silicone compound. The compositions and methods are employed to improve the quality of the keratinous fibers.

Cosmetic Compositions Containing Oxazoline Functionalized Polymers And Carboxyl Group-Containing Polymers

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US Patent:
20200069557, Mar 5, 2020
Filed:
Aug 31, 2018
Appl. No.:
16/118824
Inventors:
- Paris, FR
Jim SINGER - South Orange NJ, US
XianZhi ZHOU - Millburn NJ, US
Jennifer HAGHPANAH - Newtown CT, US
Charles SHAW - Seattle WA, US
Assignee:
L'OREAL - Paris
International Classification:
A61K 8/898
A61K 8/81
A61K 8/891
A61Q 5/00
A45D 19/16
Abstract:
Disclosed are compositions, systems and methods for treating keratinous fibers such as hair. The compositions and systems comprise an oxazoline functionalized polymer and a carboxyl group-containing polymer. The compositions and methods are employed to improve the quality of the keratinous fibers.

Cosmetic Compositions Containing Oxazoline Functionalized Polymers And Compound Having At Least One Nucleophilic Site Capable Of Reacting With The At Least One Oxazoline Functionalized Compounds

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US Patent:
20200069559, Mar 5, 2020
Filed:
Aug 31, 2018
Appl. No.:
16/118669
Inventors:
- Paris, FR
Jim SINGER - South Orange NJ, US
XianZhi ZHOU - Millburn NJ, US
Jennifer HAGHPANAH - Newtown CT, US
Charles SHAW - Seattle WA, US
Assignee:
L'OREAL - Paris
International Classification:
A61K 8/899
A61K 8/81
A61K 8/892
A61K 8/67
A61K 8/35
A61Q 5/12
A61Q 5/00
Abstract:
Disclosed are compositions, systems and methods for treating keratinous fibers such as hair. The compositions and systems comprise an oxazoline functionalized polymer and a compound having at least one nucleophilic site capable of reacting with the at least one oxazoline functionalized compound and chosen from hydroxyl group-containing compounds, thiol group-containing compounds, and a mixture thereof. The compositions and methods are employed to improve the quality of the keratinous fibers.
Xianzhi Z Zhou from Rockville, MD, age ~56 Get Report