William M Wattengel

7910690, Mar 22, 2011

Apr 27, 2007

11/741611

Timothy A. Ringeisen - Exton PA, US
William Christian Wattengel - West Chester PA, US

Kensey Nash BVF Technology, LLC - Wilmington DE

C07K 17/00

528502D, 530350, 530356, 623 1111

This invention includes malleable, biodegradable, fibrous compositions for application to a tissue site in order to promote or facilitate new tissue growth. One aspect of this invention is a fibrous component that provides unique mechanical and physical properties. The invention may be created by providing a vessel containing a slurry, said slurry comprising a plurality of natural or synthetic polymer fibers and at least one suspension fluid, wherein the polymer fibers are substantially evenly dispersed and randomly oriented throughout the volume of the suspension fluid; applying a force, e. g. , centrifugal, to said vessel containing said slurry, whereupon said force serves to cause said polymer fibers to migrate through the suspension fluid and amass at a furthest extent of the vessel, forming a polymer material, with said polymer material comprising polymer fibers of sufficient length and sufficiently viscous, interlaced, or interlocked to retard dissociation of said polymer fibers.

8188229, May 29, 2012

Feb 14, 2011

13/027025

Timothy A. Ringeisen - Exton PA, US
William Christian Wattengel - West Chester PA, US

Kensey Nash BVF Technology, LLC - Wilmington DE

C07K 17/00

530350, 530356, 528502 D, 623 1111

This invention includes malleable, biodegradable, fibrous compositions for application to a tissue site in order to promote or facilitate new tissue growth. One aspect of this invention is a fibrous component that provides unique mechanical and physical properties. The invention may be created by providing a vessel containing a slurry, said slurry comprising a plurality of natural or synthetic polymer fibers and at least one suspension fluid, wherein the polymer fibers are substantially evenly dispersed and randomly oriented throughout the volume of the suspension fluid; applying a force, e. g. , centrifugal, to said vessel containing said slurry, whereupon said force serves to cause said polymer fibers to migrate through the suspension fluid and amass at a furthest extent of the vessel, forming a polymer material, with said polymer material comprising polymer fibers of sufficient length and sufficiently viscous, interlaced, or interlocked to retard dissociation of said polymer fibers.

8551514, Oct 8, 2013

Dec 15, 2008

12/316798

Timothy A. Ringeisen - Exton PA, US
William Christian Wattengel - West Chester PA, US

Kensey Nash BVF Technology LLC - Wilmington DE

A61F 2/02

424425

The invention concerns a dried form of a porous polymer gel material which may be rehydrated and placed under pressure or compression to induce salvation, thereby forming a high concentration gel, in the form of an injectable viscous putty or dough, which may be implantated in the body.

20050186240, Aug 25, 2005

Feb 23, 2004

10/785665

Timothy Ringeisen - Exton PA, US
William Wattengel - West Chester PA, US

A61K009/14

424423000, 424486000

The invention concerns a dried form of a porous polymer gel material which may be rehydrated and placed under pressure or compression to induce solvation, thereby forming a high concentration gel, in the form of an injectable viscous putty or dough, which may be implantated in the body.

20060002980, Jan 5, 2006

Jul 8, 2005

11/178175

Timothy Ringeisen - Exton PA, US
William Wattengel - West Chester PA, US

A61F 2/00
A61K 31/728

424426000, 514054000, 514055000

This invention includes malleable, biodegradable, fibrous compositions for application to a tissue site in order to promote or facilitate new tissue growth. One aspect of this invention is a fibrous component that provides unique mechanical and physical properties. The invention may be created by providing a vessel containing a slurry, said slurry comprising a plurality of natural or synthetic polymer fibers and at least one suspension fluid, wherein the polymer fibers are substantially evenly dispersed and randomly oriented throughout the volume of the suspension fluid; applying a force, e.g., centrifugal, to said vessel containing said slurry, whereupon said force serves to cause said polymer fibers to migrate through the suspension fluid and amass at a furthest extent of the vessel, forming a polymer material, with said polymer material comprising polymer fibers of sufficient length and sufficiently viscous, interlaced, or interlocked to retard dissociation of said polymer fibers.

20100331865, Dec 30, 2010

Jun 30, 2009

12/495611

Gino Bradica - Mullica Hill NJ, US
William Christian Wattengel - West Chester PA, US
Timothy A. Ringeisen - Exton PA, US

A61B 17/08

606151

Tissue implants prepared for the repair of tissues, especially avascular tissues such as cartilage. One embodiment presents an electric potential capable of receiving and accumulating desirable factors or molecules from surrounding fluid when exposed to dynamic loading. In another embodiment the implant promotes tissue conduction by retarding, restricting and controlling cellular invasion through use of gradients until competent tissue forms. Further embodiments of the tissue implants may be formed into a multi-phasic device that provides deep tissue mechanical stimulus by conduction of mechanical and fluid forces experienced at the surface of the implant.

20190343986, Nov 14, 2019

Jul 29, 2019

16/524435

- Heerlen, NL
William Christopher WATTENGEL - Exton PA, US

A61L 27/16
A61F 2/28
A61L 27/54
A61B 17/68
A61B 17/70
A61B 17/72
A61L 26/00
A61L 27/46
A61L 27/48
A61L 27/52
A61L 27/58
C08H 1/06
C08L 5/04
C08L 5/08
A61F 2/00
A61F 2/24
A61F 2/30
A61F 2/44
A61L 27/12
A61L 27/26
A61L 27/56
A61L 27/24
A61L 27/38
A61L 27/18
A61L 27/20
A61L 27/22
A61L 27/36
C08L 89/06
C08L 67/04

This invention includes malleable, biodegradable, fibrous compositions for application to a tissue site in order to promote or facilitate new tissue growth. One aspect of this invention is a fibrous component that provides unique mechanical and physical properties. The invention may be created by providing a vessel containing a slurry, said slurry comprising a plurality of natural or synthetic polymer fibers and at least one suspension fluid, wherein the polymer fibers are substantially evenly dispersed and randomly oriented throughout the volume of the suspension fluid; applying a force, e.g., centrifugal, to said vessel containing said slurry, whereupon said force serves to cause said polymer fibers to migrate through the suspension fluid and amass at a furthest extent of the vessel, forming a polymer material, with said polymer material comprising polymer fibers of sufficient length and sufficiently viscous, interlaced, or interlocked to retard dissociation of said polymer fibers.

20170203007, Jul 20, 2017

Feb 28, 2017

15/444463

- Exton PA, US
William Christopher WATTENGEL - Exton PA, US

A61L 27/56
A61L 27/54
A61L 27/12
A61F 2/24
A61F 2/44
A61F 2/28
A61F 2/00
A61F 2/30
A61L 27/26
A61L 27/24

This invention includes malleable, biodegradable, fibrous compositions for application to a tissue site in order to promote or facilitate new tissue growth. One aspect of this invention is a fibrous component that provides unique mechanical and physical properties. The invention may be created by providing a vessel containing a slurry, said slurry comprising a plurality of natural or synthetic polymer fibers and at least one suspension fluid, wherein the polymer fibers are substantially evenly dispersed and randomly oriented throughout the volume of the suspension fluid; applying a force, e.g., centrifugal, to said vessel containing said slurry, whereupon said force serves to cause said polymer fibers to migrate through the suspension fluid and amass at a furthest extent of the vessel, forming a polymer material, with said polymer material comprising polymer fibers of sufficient length and sufficiently viscous, interlaced, or interlocked to retard dissociation of said polymer fibers.