US Patent:
20020119947, Aug 29, 2002
Inventors:
William Sarill - Arlington MA, US
Thomas Brennan - Nyack NY, US
International Classification:
A61K031/714
A61K031/4172
A61K031/409
A61K031/405
A61K031/401
A61K031/198
US Classification:
514/052000, 514/185000, 514/419000, 514/400000, 514/561000, 514/564000, 514/565000, 514/566000, 514/423000, 514/410000, 514/562000
Abstract:
Novel compositions cobalamin and related corrinoids, and uses thereof, are disclosed. The novel compositions include a corrin, a first amino acid having a side chain which includes a basic or positively charged moiety; and a second amino acid with an uncharged side chain which includes at least one heteroatom. The compositions are useful for, inter alia, treatment of cobalamin deficiency.