William A Beck

20090325200, Dec 31, 2009

Mar 23, 2007

12/293915

William T. Beck - Chicago IL, US
Xiaolong He - Palatine IL, US

G01N 33/574
C12N 5/00

435 723, 435377

The present invention provides a method of diagnosing cancer in a mammalian subject comprising measuring the level of polypyrimidine-tract binding protein (PTB) in a tissue sample obtained from the subject. An elevated level of PTB in the sample comparing to a normal control is indicative the subject is positively diagnosed with cancer. The present invention furthers provides a method for inhibiting proliferation of a mammalian cancer cell. The method comprises suppressing the level of polypyrimidine-tract binding protein (PTB) in the cell.

20100144838, Jun 10, 2010

Dec 1, 2009

12/628808

William T. Beck - Chicago IL, US
Xiaolong He - Palatine IL, US

A61K 31/7088
A61P 35/00
G01N 33/53
C12Q 1/68

514 44 A, 435 721, 435 6

Provided herein are methods and materials for identifying compounds that modulate polypyrimidine tract binding protein (PTB), a protein that functions as a negative regulator of pre-mRNA splicing by blocking the inclusion of numerous alternative exons into mRNA.

39673723, Jul 6, 1976

Mar 31, 1972

5/239998

William P. Beck - Westchester IL
Francis L. Carr - Downers Grove IL
Howard R. Chapin - Park Ridge IL
Gordon Bast - West Chicago IL

Sunbeam Corporation - Chicago IL

B26B 1910
B26B 1904

30 341

An electric shaver having two spaced shaving heads with a long hair clipper or trimmer positioned therebetween with the trimmer being adjustable to a retracted position or to an extended position in which it is spaced from the shaving heads and is adaptable to trimming sideburns, moustaches and the like. The trimmer is slidably supported on a head frame which is detachably mounted with respect to a motor enclosing housing. The trimmer is spring biased into engagement with cam means carried by the housing and adapted to position the trimmer at various heights with respect to the shaving heads. The shaving heads include foil combs carried by the head frame and spring biased against cutters which are mounted on the housing and supported for reciprocation on friction reducing ball rollers. The motor drives the trimmer and shaving cutters by means of a double eccentric carried by the motor shaft and a pair of coaxially pivoted levers which oscillate in an out-of-phase relationship.

43265960, Apr 27, 1982

Jul 10, 1980

6/167770

William P. Beck - Westchester IL

Borg-Erickson Corporation - Chicago IL

G01G 2332
G01G 314

177178

An electronic weighing apparatus includes a switch mounted on a base surface thereof, actuated by an actuating member biased to support a portion of the base. When weight is applied to the apparatus, the actuating member is moved to a depressed position, thereby automatically energizing the apparatus. In addition, a tab is mounted to the base near the switch. Vertical forces can be applied to the tab to depress the actuating member without disturbing the zero position of the weighing apparatus. Furthermore, the apparatus includes an optical coded disc with a plurality of concentric code tracks. A light guide conducts light to a line on the disc which is parallel to but offset from a radius of the disc. Photosensors are positioned on the other side of the disc, opposed to the light guide. A mask is interposed between the photosensors and the light guide, which mask defines a plurality of apertures, each of which is oriented parallel to a radius of a respective code track such that no two of the apertures are parallel.

41331036, Jan 9, 1979

Nov 4, 1977

5/848405

William P. Beck - Westchester IL

Sunbeam Corporation - Chicago IL

B26B 1900

30 43

A comb assembly for an electric dry shaver is provided with a perforated central comb panel and two end comb panels disposed adjacent the edges of the central comb panel and having long hair slots. The end panels and the central comb panels are separately fabricated from stock materials of different predetermined thicknesses and assembled to form an accurate and smoothly interfitting comb assembly. Thus, the thickness of the central comb panel is determined independent of the end comb panel thickness. The central comb panel, fabricated from a stock material of a uniformly thinner thickness than that of the end panels, requires no grinding in the fabrication of the comb and thus results in a more uniform thinner comb than obtained with grinding operations. The separately fabricated, flexible central and end comb panels, after being fabricated with the desired predetermined patterns of perforations and elongated slots, are secured over a multiply arched comb support structure which includes a number of thin support ribs. The central and end comb panels are secured to the comb support structure by integrally formed retaining clip portions that interfit with corresponding extending tabs of the comb support structure.

41504828, Apr 24, 1979

Nov 14, 1977

5/851152

William P. Beck - Westchester IL
Francis L. Carr - Downers Grove IL

Sunbeam Corporation - Chicago IL

B26B 1904

30 439

A modular cutter assembly for an electric dry shaver of the type wherein movable cutter assemblies are disposed in shearing relationship with a flexible comb assembly. Each of the cutter assemblies is easily removable or replaceable as a modular unit from the cutter drive shafts of the shaver head. The modular cutter assemblies are assembled by the insertion of alternating cutter blade element assemblies and cutter blade spacers within a cutter support structure with a predetermined interrelationship and orientation of the aforementioned subassembly parts to achieve a consistently and accurately disposed cutter system. Each of the plurality of cutting blade element assemblies of each cutter assembly of the shaver is formed by two individual cutter blades having oppositely inclined outwardly angled cutting edges providing a desirable cutting edge geometry in a back-to-back relationship heretofore achievable only by the undercut grinding in two inclined directions of a single cutter blade or by coining to achieve a similar configuration. The two back-to-back individual cutter blades utilized to form the single cutter blade element assembly of each cutter assembly are fabricated as identical parts and mounted in a back-to-back reverse orientation to thereby achieve the oppositely inclined outwardly angled edges of the cutter blade pair. The individual cutter blades are fabricated with integrally formed biasing members which urge the cutter blade edges into accurate conformance with the comb assembly and establish a uniform consistent biasing force during operation.

40855031, Apr 25, 1978

Dec 23, 1974

5/535949

William P. Beck - Westchester IL
Francis L. Carr - Downers Grove IL
Jerry P. Gronwick - Park Ridge IL

Sunbeam Corporation - Chicago IL

B26B 1910

30 341

Electric dry shaver having a shaving head and a trimmer for cutting long hair, the trimmer being equipped with adjustable means to control the height or length to which the trimmer may cut hair. Control means within the shaver are provided to adjust the height of the trimmer guard and to retain it in the selected position.