Inventors:
Wenyuan Shi - Los Angeles CA, US
Li Chen - Los Angeles CA, US
Qing-yi Lu - Los Angeles CA, US
David Heber - Los Angeles CA, US
Maxwell H. Anderson - Seattle WA, US
Assignee:
The Regents of the University of California - Oakland CA
International Classification:
A61K 31/58
A61K 31/70
A01N 43/04
C07J 71/00
Abstract:
The present invention is based on the discovery that certain chemical compounds isolated from Chinese medicinal herbs are useful as anti-microbial agents, e. g. , anti-bacterial agents, anti-fungal agents, and the like. In particular, the present invention provides compositions useful for treating microbial infections such as, for example, oral microbial infections, including periodontal disease and dental caries.