Search

Wenxin Gu

from Concord, MA
Age ~50
Get Report
Connected to:
Alexander Gu, 34An Gu, 30Chaoning Gu, 62Crystal Gu, 33Fred Y Gu, 58Grace Y Gu, 64Hanna Gu, 44Helena Y Gu, 32Hong C Gu, 58Howard H Gu, 66

Wenxin Gu Phones & Addresses

  • Concord, MA
  • Somerville, MA
  • Evanston, IL

Publications

Us Patents

Cyclic Peptide Antitumor Agents

View page
US Patent:
8058244, Nov 15, 2011
Filed:
Mar 11, 2010
Appl. No.:
12/722026
Inventors:
Richard B. Silverman - Northbrook IL, US
Shouxin Liu - Evanston IL, US
Wenxin Gu - Evanston IL, US
Thomas E. Adrian - Chicago IL, US
Gerald A. Soff - Wilmette IL, US
Assignee:
Northwestern University - Evanston IL
International Classification:
A61K 38/00
US Classification:
514 193
Abstract:
Cyclic peptide compounds and derivatives thereof having antitumor activity as shown by treatment of human melanoma, pancreatic, breast, prostate cancer cells.

Cyclic Peptide Antitumor Agents

View page
US Patent:
8492345, Jul 23, 2013
Filed:
Nov 14, 2011
Appl. No.:
13/295653
Inventors:
Richard B. Silverman - Northbrook IL, US
Shouxin Liu - Evanston IL, US
Wenxin Gu - Evanston IL, US
Thomas E. Adrian - Chicago IL, US
Gerald A. Soff - Wilmette IL, US
Assignee:
Northwestern University - Evanston IL
International Classification:
A61K 38/00
A61P 35/00
US Classification:
514 193, 514 194, 514 195
Abstract:
Cyclic peptide compounds and derivatives thereof having antitumor activity as shown by treatment of human melanoma, pancreatic, breast, prostate cancer cells.

Cyclic Peptide Antitumor Agents

View page
US Patent:
20050159346, Jul 21, 2005
Filed:
Oct 8, 2004
Appl. No.:
10/962168
Inventors:
Richard Silverman - Northbrook IL, US
Shouxin Liu - Evanston IL, US
Wenxin Gu - Evanston IL, US
Thomas Adrian - Chicago IL, US
Gerald Soff - Wilmette IL, US
International Classification:
A61K038/12
C07K005/12
US Classification:
514009000, 530317000
Abstract:
Cyclic peptide compounds and derivatives thereof having antitumor activity as shown by treatment of human melanoma, pancreatic, breast, prostate cancer cells.

Inhibitors Of Influenza Viruses Replication

View page
US Patent:
20120171245, Jul 5, 2012
Filed:
Dec 15, 2011
Appl. No.:
13/327206
Inventors:
Paul S. Charifson - Framingham MA, US
Michael P. Clark - Concord MA, US
Upul K. Bandarage - Lexington MA, US
Randy S. Bethiel - Lexington MA, US
John J. Court - Littleton MA, US
Hongbo Deng - Southborough MA, US
Ioana Davies - Watertown MA, US
John P. Duffy - Northborough MA, US
Luc J. Farmer - Montreal, CA
Huai Gao - Arlington MA, US
Wenxin Gu - Concord MA, US
Dylan H. Jacobs - Everett MA, US
Joseph M. Kennedy - Charlestown MA, US
Mark W. Ledeboer - Acton MA, US
Brian Ledford - Norton MA, US
Francois Maltais - Tewksbury MA, US
Emanuele Perola - Brookline MA, US
Tiansheng Wang - Concord MA, US
M. Woods Wannamaker - Bolton MA, US
Randal Byrn - Wayland MA, US
Yi Zhou - Lexington MA, US
Chao Lin - Winchester MA, US
Min Jiang - Lexington MA, US
Steven Jones - Hyde Park MA, US
Ursula A. Germann - Newton MA, US
Assignee:
VERTEX PHARMACEUTICALS INCORPORATED - Cambridge MA
International Classification:
A61K 39/145
A61K 31/506
A61K 31/5377
A61K 31/551
A61K 31/553
A01P 1/00
A01N 43/90
C07D 491/08
C07D 491/107
A61P 31/16
A61P 37/04
C07D 471/04
A61K 31/55
US Classification:
4242091, 544328, 514256, 544122, 5142345, 51421018, 544327, 544295, 51425218, 540575, 514218, 540544, 51421115, 540524, 51421208, 51421021, 540599, 540488, 51421103, 544230, 51425505, 51421016, 51421706
Abstract:
Methods of inhibiting the replication of influenza viruses in a biological sample or patient, of reducing the amount of influenza viruses in a biological sample or patient, and of treating influenza in a patient, comprises administering to said biological sample or patient an effective amount of a compound represented by Structural Formula (I):or a pharmaceutically acceptable salt thereof, wherein the values of Structural Formula (IA) are as described herein. A compound is represented by Structural Formula (IA) or a pharmaceutically acceptable salt thereof, wherein the values of Structural Formula (IA) are as described herein. A pharmaceutical composition comprises an effective amount of such a compound or pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier, adjuvant or vehicle.

Inhibitors Of Influenza Viruses Replication

View page
US Patent:
20130345218, Dec 26, 2013
Filed:
Jun 14, 2013
Appl. No.:
13/918115
Inventors:
Michael P. Clark - Concord MA, US
Upul K. Bandarage - Lexington MA, US
Hongbo Deng - Southborough MA, US
Ioana Davies - Watertown MA, US
John P. Duffy - Northborough MA, US
Luc J. Farmer - Montreal, CA
Huai Gao - Arlington MA, US
Wenxin Gu - Concord MA, US
Joseph M. Kennedy - Charlestown MA, US
Mark W. Ledeboer - Acton MA, US
Brian Ledford - Norton MA, US
Francois Maltais - Tewksbury MA, US
Emanuele Perola - Brookline MA, US
Marion W. Wannamaker - Bolton MA, US
Tiansheng Wang - Concord MA, US
Francesco G. Salituro - Marlborough MA, US
International Classification:
C07D 471/04
US Classification:
5142345, 544331, 514275, 544127, 546113, 514300, 544182, 514242, 544212, 514245
Abstract:
Methods of inhibiting the replication of influenza viruses in a biological sample or patient, of reducing the amount of influenza viruses in a biological sample or patient, and of treating influenza in a patient, comprises administering to said biological sample or patient an effective amount of a compound represented by Structural Formula (I):or a pharmaceutically acceptable salt thereof, wherein the values of Structural Formula (I) are as described herein. A compound is represented by Structural Formula (I) or a pharmaceutically acceptable salt thereof, wherein the values of Structural Formula (I) are as described herein. A pharmaceutical composition comprises an effective amount of such a compound or pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier, adjuvant or vehicle.

Pteridinone Compounds And Uses Thereof

View page
US Patent:
20220363685, Nov 17, 2022
Filed:
Mar 1, 2021
Appl. No.:
17/188132
Inventors:
- Boston MA, US
Guy BEMIS - Boston MA, US
Michael BOYD - Boston MA, US
David DEININGER - Boston MA, US
Hongbo DENG - Southborough MA, US
Warren DORSCH - Boston MA, US
Wenxin GU - Concord MA, US
Russell R. HOOVER - Harvard MA, US
Mark Willem LEDEBOER - Boston MA, US
Brian LEDFORD - Boston MA, US
Francois MALTAIS - Boston MA, US
Marina PENNEY - Acton MA, US
Darin TAKEMOTO - Belmont MA, US
Nathan D. WAAL - Cambridge MA, US
Tiansheng WANG - Concord MA, US
Pan LI - Lexington MA, US
International Classification:
C07D 487/04
C07D 491/20
C07D 487/14
C07D 519/00
C07D 471/14
C07D 498/04
C07D 471/04
Abstract:
The present invention provides compounds of Formula I, or pharmaceutically acceptable salts thereof, pharmaceutical compositions thereof, and methods of use thereof for treating cellular proliferative disorders (e.g., cancer).

Substituted Quinoxaline Dna-Pk Inhibitors

View page
US Patent:
20210236505, Aug 5, 2021
Filed:
Feb 9, 2021
Appl. No.:
17/171061
Inventors:
- Boston MA, US
Paul S. Charifson - Framingham MA, US
Qing Tang - Acton MA, US
Steven M. Ronkin - Watertown MA, US
Katrina Lee Jackson - Cambridge MA, US
Albert Charles Pierce - Cambridge MA, US
David J. Lauffer - Stow MA, US
Pan Li - Lexington MA, US
Simon Giroux - Cambridge MA, US
Jinwang Xu - Framingham MA, US
Kevin Michael Cottrell - Cambridge MA, US
Mark A. Morris - Somerville MA, US
Nathan D. Waal - Cambridge MA, US
John J. Court - Littleton MA, US
Wenxin Gu - Concord MA, US
Hongbo Deng - Southborough MA, US
Assignee:
Vertex Pharmaceuticals Incorporated - Boston MA
International Classification:
A61K 31/5377
C07D 513/04
A61K 31/506
A61K 31/5386
C07D 241/40
C07D 401/14
C07D 403/12
C07D 403/14
C07D 405/12
C07D 405/14
C07D 413/12
C07D 417/12
C07D 471/04
C07D 473/40
C07D 475/00
C07D 487/04
C07D 491/048
C07D 498/08
C07D 413/04
C07D 241/44
C07D 491/052
C07D 241/42
C07D 271/12
C07D 401/12
C07D 413/14
C07D 491/056
C07D 491/08
Abstract:
The present invention relates to compounds useful as inhibitors of DNA-PK. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders.

Dna-Pk Inhibitors

View page
US Patent:
20210069203, Mar 11, 2021
Filed:
Sep 17, 2020
Appl. No.:
17/023597
Inventors:
- Boston MA, US
Paul S. Charifson - Framingham MA, US
Qing Tang - Acton MA, US
Steven M. Ronkin - Watertown MA, US
Katrina Lee Jackson - Cambridge MA, US
Albert Charles Pierce - Cambridge MA, US
David J. Lauffer - Stow MA, US
Pan Li - Lexington MA, US
Simon Giroux - Cambridge MA, US
Jinwang Xu - Framingham MA, US
Kevin Michael Cottrell - Cambridge MA, US
Mark A. Morris - Somerville MA, US
Nathan D. Waal - Cambridge MA, US
John J. Court - Littleton MA, US
Wenxin Gu - Concord MA, US
Hongbo Deng - Southborogh MA, US
Assignee:
Vertex Pharmaceuticals Incorporated - Boston MA
International Classification:
A61K 31/5377
C07D 513/04
A61K 31/506
A61K 31/5386
C07D 241/40
C07D 401/14
C07D 403/12
C07D 403/14
C07D 405/12
C07D 405/14
C07D 413/12
C07D 417/12
C07D 471/04
C07D 473/40
C07D 475/00
C07D 487/04
C07D 491/048
C07D 498/08
C07D 413/04
C07D 241/44
C07D 491/052
C07D 241/42
C07D 271/12
C07D 401/12
C07D 413/14
C07D 491/056
C07D 491/08
Abstract:
The present invention relates to compounds useful as inhibitors of DNA-PK. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders.
Control profile
Wenxin Gu from Concord, MA, age ~50 Get Report