Inventors:
William W. Armstrong - Mill Neck NY
Charles E. Moppett - Mystic CT
Wendell W. Windisch - Groton CT
Assignee:
Pfizer Inc. - New York NY
International Classification:
C07D49914
Abstract:
The 1:2 N,N'-dibenzylethylenediamine, the N-benzyl-2-phenylethylamine and the dibenzylamine salts of penicillanic acid 1,1-dioxide, a well-known betalactamase inhibitor, are sparingly soluble in water. Accordingly they are valuable as slow release (depot) forms of penicillanic acid 1,1-dioxide, particularly for use in conjunction with slow release (depot) forms of penicillin and cephalosporin antibiotics, in the chemotherapy of bacterial infections in mammals.