US Patent:
20120232054, Sep 13, 2012
Inventors:
Kevin J. Moriarty - East Norrion PA, US
Dora Do-York Wong - East Norrison PA, US
Zenon Konteatis - Chatham Twp. NJ, US
Kristofer Moffett - Middletown CT, US
Younghee Lee - Blue Bell PA, US
Wenchun Chao - Portage MI, US
Assignee:
LOCUS PHARMACEUTICALS, INC. - West Conshohocken PA
International Classification:
A61K 31/53
A61P 37/06
A61K 31/5377
A61P 7/02
A61P 35/00
C07D 487/04
A61P 37/08
A61P 29/00
US Classification:
51421021, 544183, 514243, 544112, 5142332
Abstract:
A compound of formula (I):wherein all symbols have the same meanings as defined in the specification; a salt thereof, a solvate thereof, an N-oxide thereof, or a prodrug thereof, has a Btk inhibitory activity, and is useful as a method for preventing and/or treating a rheumatoid arthritis, an autoimmune disease, a B cell lymphoma of cancer, and the like.