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Wayne Kindsvogel Phones & Addresses

  • 6014 24Th Ave NE, Seattle, WA 98115 (206) 779-2154
  • Enumclaw, WA
  • Atlanta, GA
  • 6014 24Th Ave NE, Seattle, WA 98115

Work

Position: Biomedical scientist

Education

Degree: Doctorates, Doctor of Philosophy School / High School: Oregon Health & Science University 1978 to 1982 Specialities: Biochemistry, Immunology

Skills

Molecular Biology • Immunology • Technology Transfer • Drug Discovery • Oncology • Molecular Immunology • Biotechnology • Genomics • Biologics • Life Sciences • Biopharmaceuticals • Cell Culture • Clinical Research • Biomarker Discovery • Elisa • Biomarkers • Lifesciences • Pharmaceutical Industry • R&D

Industries

Biotechnology

Resumes

Resumes

Wayne Kindsvogel Photo 1

Biomedical Scientist

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Location:
Seattle, WA
Industry:
Biotechnology
Work:

Biomedical Scientist

Intellectual Ventures
Scientific Program Manager Bio-Medicine

Zymogenetics Oct 1982 - Feb 2008
Principal Scientist
Education:
Oregon Health & Science University 1978 - 1982
Doctorates, Doctor of Philosophy, Biochemistry, Immunology
Enumclaw Senior High School
Skills:
Molecular Biology
Immunology
Technology Transfer
Drug Discovery
Oncology
Molecular Immunology
Biotechnology
Genomics
Biologics
Life Sciences
Biopharmaceuticals
Cell Culture
Clinical Research
Biomarker Discovery
Elisa
Biomarkers
Lifesciences
Pharmaceutical Industry
R&D

Publications

Us Patents

Interferon-Epsilon

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US Patent:
6544505, Apr 8, 2003
Filed:
Oct 4, 2001
Appl. No.:
09/971843
Inventors:
Darrell C. Conklin - Seattle WA
Francis J. Grant - Seattle WA
Mark W. Rixon - Issaquah WA
Wayne Kindsvogel - Seattle WA
Assignee:
ZymoGenetics, Inc. - Seattle WA
International Classification:
A61K 3821
US Classification:
424 854, 4241851, 530350, 530351, 435 6951
Abstract:
Interferons represent an important class of biopharmaceutical products, which have a proven track record in the treatment of a variety of medical conditions, including the treatment of certain autoimmune diseases, the treatment of particular cancers, and the enhancement of the immune response against infectious agents. To date, four types of interferons have been found in humans: interferon-, interferon-, interferon-, and interferon-. The present invention provides new forms of human and murine interferon, âinterferon- ,â which have applications in diagnosis and therapy.

Islet Cell Antigen 1851

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US Patent:
6627735, Sep 30, 2003
Filed:
Jun 7, 2001
Appl. No.:
09/876527
Inventors:
Wayne Kindsvogel - Seattle WA
Laura J. Jelinek - Seattle WA
Paul O. Sheppard - Redmond WA
William A. Hagopian - Seattle WA
James M. LaGasse - Seattle WA
Assignee:
ZymoGenetics, Inc. - Seattle WA
International Classification:
C07K 100
US Classification:
530350, 4241851
Abstract:
A mammalian islet cell antigen polypeptide involved in the development of insulin-dependent diabetes mellitus (IDDM) is disclosed. This islet cell antigen polypeptide, 1851, was found to contain regions of homology to the protein tyrosine phosphatase family. Methods for diagnosis and treatment, including use in immunoprecipitation assays and the induction of immune tolerance using the recombinant mammalian polypeptides and antibodies specific to mammalian islet cell antigen 1851 polypeptides are presented.

Mouse Cytokine Receptor

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US Patent:
6875845, Apr 5, 2005
Filed:
Mar 4, 2002
Appl. No.:
10/090365
Inventors:
Scott R. Presnell - Tacoma WA, US
Wenfeng Xu - Mukilteo WA, US
Wayne Kindsvogel - Seattle WA, US
Zhi Chen - Bellevue WA, US
Assignee:
ZymoGenetics, Inc. - Seattle WA
International Classification:
C07K014/705
C07K014/475
US Classification:
530351, 530810, 5303873, 514 12
Abstract:
Cytokines and their receptors have proven usefulness in both basic research, animal models, and as therapeutics. The present invention provides a new cytokine receptor designated as “mouse Zcytor16,” which can bind and antagonize the IL-TIF cytokine.

Human Cytokine Receptor

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US Patent:
6897292, May 24, 2005
Filed:
Dec 1, 2000
Appl. No.:
09/728911
Inventors:
Scott R. Presnell - Tacoma WA, US
Wenfeng Xu - Mukilteo WA, US
Wayne Kindsvogel - Seattle WA, US
Zhi Chen - Seattle WA, US
Assignee:
ZymoGenetics, Inc. - Seattle WA
International Classification:
C07K014/715
C07K014/725
C07K014/75
C07K016/46
C07K019/00
US Classification:
530350, 530351, 5303873, 530402
Abstract:
Cytokines and their receptors have proven usefulness in both basic research and as therapeutics. The present invention provides a new human cytokine receptor designated as “Zcytor16. ”.

Cytokine Protein Family

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US Patent:
7038032, May 2, 2006
Filed:
Apr 19, 2002
Appl. No.:
10/127816
Inventors:
Paul O. Sheppard - Granite Falls WA, US
Brian A. Fox - Seattle WA, US
Kevin M. Klucher - Bellevue WA, US
David W. Taft - Kirkland WA, US
Wayne Kindsvogel - Seattle WA, US
Assignee:
ZymoGenetics, Inc. - Seattle WA
International Classification:
C07H 21/04
C07H 21/02
C12P 21/06
US Classification:
536 235, 536 231, 435 691
Abstract:
The present invention relates to polynucleotide and polypeptide molecules for zcyto20, zcyto21, zcyto22, zycto24, and zcyto25 proteins which are most closely related to interferon-α at the amino acid sequence level. The receptor for this protein family is a class II cytokine receptor. The present invention includes methods of reducing viral infections and increasing monocyte counts. The present invention also includes antibodies to the zcyto20 polypeptides, and methods of producing the polynucleotides and polypeptides.

Soluble Zcytor11 Cytokine Receptors

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US Patent:
7045498, May 16, 2006
Filed:
Aug 8, 2001
Appl. No.:
09/925055
Inventors:
Wayne R. Kindsvogel - Seattle WA, US
Stavros Topouzis - Seattle WA, US
Assignee:
ZymoGenetics, Inc. - Seattle WA
International Classification:
A61K 38/19
A61K 45/00
C07K 14/47
US Classification:
514 2, 530351, 424 852
Abstract:
Novel polypeptide combinations, polynucleotides encoding the polypeptides, and related compositions and methods are disclosed for soluble zcytor11 receptors that may be used as novel cytokine antagonists, and within methods for detecting ligands that stimulate the proliferation and/or development of hematopoietic, lymphoid and myeloid cells in vitro and in vivo. Ligand-binding receptor polypeptides and antibodies can also be used to block TIF activity in vitro and in vivo, and may be used in conjunction with TIF and other cytokines to selectively stimulate the immune system. The present invention also includes methods for producing the protein, uses therefor and antibodies thereto.

Methods For Treating Viral Infection Using Il-28 And Il-29

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US Patent:
7135170, Nov 14, 2006
Filed:
Oct 23, 2003
Appl. No.:
10/691923
Inventors:
Kevin M. Klucher - Bellevue WA, US
Pallavur V. Sivakumar - Seattle WA, US
Wayne R. Kindsvogel - Seattle WA, US
Katherine E. Henderson - Seattle WA, US
Assignee:
ZymoGenetics, Inc. - Seattle WA
International Classification:
A61K 45/00
A61K 38/19
US Classification:
424 852, 4241611, 514 12
Abstract:
IL-28A, IL-28B, IL-29, and certain mutants thereof have been shown to have antiviral activity on a spectrum of viral species. Of particular interest is the antiviral activity demonstrated on viruses that infect liver, such as hepatitis B virus and hepatitis C virus. In addition, IL-28A, IL-28B, IL-29, and mutants thereof do not exhibit some of the antiproliferative activity on hematopoietic cells that is observed with interferon treatment. Without the immunosuppressive effects accompanying interferon treatment, IL-28A, IL-28B, and IL-29 will be useful in treating immunocompromised patients for viral infections.

Isolated Polynucleotides Encoding A Human Cytokine Receptor Human Cytokine Receptor

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US Patent:
7189839, Mar 13, 2007
Filed:
Nov 5, 2004
Appl. No.:
10/981998
Inventors:
Scott R. Presnell - Tacoma WA, US
Wenfeng Xu - Mukilteo WA, US
Wayne Kindsvogel - Seattle WA, US
Zhi Chen - Seattle WA, US
Assignee:
ZymoGenetics, Inc. - Seattle WA
International Classification:
C07H 21/04
C12N 5/10
C12N 15/00
US Classification:
536 235, 536 234, 4353201, 4352523, 435455, 435 691
Abstract:
Cytokines and their receptors have proven usefulness in both basic research and as therapeutics. The present invention provides a new human cytokine receptor designated as “Zcytor16. ”.
Wayne R Kindsvogel from Seattle, WA, age ~77 Get Report