Resumes
Resumes
Wayne Hubbell Phones & Addresses
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6805 County Road 1820, West Plains, MO 65775 (417) 277-5441
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Pomona, CA
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6184 County Road 4750, Pomona, MO 65789 (909) 223-6526
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Castro Valley, CA
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Ontario, CA
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Garden Grove, CA
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Redwood Valley, CA
Publications
Us Patents
Thiol Reactive Liposomes
View pageUS Patent:
44290080, Jan 31, 1984
Filed:
Dec 10, 1981
Appl. No.:
6/329211
Inventors:
Frank J. Martin - San Francisco CA
Demetrios P. Papahadjopoulos - Lafayette CA
Wayne L. Hubbell - Orinda CA
Demetrios P. Papahadjopoulos - Lafayette CA
Wayne L. Hubbell - Orinda CA
Assignee:
The Regents of the University of California - Berkeley CA
International Classification:
B01J 1302
B32B 902
B32B 902
US Classification:
4284022
Abstract:
Liposomes are provided which have a plurality of thiol reactive groups extending outward of the liposomal bilayer. The liposomes form stable covalent bonds with ligands having thiol groups, such as Fab' fragments. Particularly preferred liposomes include maleimide moieties as the thiol reactive groups. The thiol reactive liposomes are usefully employed in agglutination assays, such as blood typing and binding inhibitions, and targeting to specific cells.