Vladimir Y Evtodienko

6599474, Jul 29, 2003

Aug 30, 2002

10/232123

Vladimir Evtodienko - Elkhart IN
Iouri Evtodienko - Elkhart IN
Lydia Dobler - Granger IN
Michael A. Van Lente - Elkhart IN

Nestec, Ltd.
Environemtal Test Systems, Inc. - Elkhart IN

G01N 2100

422 56, 422 61, 436 95, 436169, 435 10, 435 15

The present invention is directed to a reagent composition for use in detection and quantification of glucose in urine comprising a first chromogenic indicator reagent combination capable of color development to indicate the presence of a lower concentration of glucose, a second chromogenic indicator reagent combination capable of color development to indicate the presence of a higher concentration of glucose, wherein the first chromogenic indicator prevents color development of the second chromogenic indicator unless the higher concentration of glucose is present, a scavenger that prevents color development of the first indicator reagent composition unless a threshold concentration of glucose is present.

6682937, Jan 27, 2004

Apr 16, 2003

10/417386

Vladimir Evtodienko - Elkhart IN
Iouri Evtodienko - Elkhart IN
Lydia Dobler - Granger IN
Michael A. Van Lente - Elkhart IN

Hach Company - Loveland CO
Nestec, Ltd. - Vevey

G01N 2175

436166, 436 95, 436169, 422 56, 422 61, 422 681, 435 10, 435 15

Methods are provided for glucose detection and quantification in urine. The methods include selecting a test device comprising a matrix impregnated with a chromogenic indicator mixture, locating the test device to promote incidental contact of same with animal urine, reading a developed indicator color after the device has been wetted with urine, and determining the animals urine glucose concentration.

6444169, Sep 3, 2002

Jun 18, 2001

09/883874

Vladimir Evtodienko - Elkhart IN
Iouri Evtodienko - Elkhart IN
Lydia Dobler - Granger IN
Michael A. Van Lente - Elkhart IN

Ralston Purina Company - St. Louis MO
Environmental Test Systems, Inc. - Elkhart IN

G01N 2100

422 56, 422 61, 436 95, 436169

Devices and test kits are provided for glucose detection and quantification in urine. The devices and kits comprise a chromogenic indicator mixture comprising a first indicator capable of color development to indicate the presence of a low-to-medium concentration of glucose, a second indicator capable of color development to indicate the presence of a higher concentration of glucose, wherein the first indicator prevents color development of the second indicator unless the higher concentration of glucose is present in the urine, and a non-chromogenic scavenger that interferes with color development of the first indicator when glucose levels are below a threshold concentration, and a carrier impregnated with the chromogenic indicator mixture.