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Vladimir Botchkarev Phones & Addresses

  • Brookline, MA
  • 113 Sparrow Rd, Stoughton, MA 02072
  • 52 Apple Valley Dr, Sharon, MA 02067 (781) 806-5140

Publications

Us Patents

Methods For Lightening Skin And Hair

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US Patent:
20090053707, Feb 26, 2009
Filed:
Nov 7, 2007
Appl. No.:
11/983207
Inventors:
Mina Yaar - Sharon MA, US
Hee-Young Park - Weston MA, US
Vladimir Botchkarev - Sharon MA, US
Barbara A. Gilchrest - Boston MA, US
International Classification:
C12Q 1/68
C12Q 1/02
C12Q 1/48
G01N 33/573
US Classification:
435 6, 435 29, 435 15, 435 74
Abstract:
Methods are described wherein the skin of a vertebrate, or the skin or hair of a mammal can be lightened by administration of an agent, e.g., protein, peptide, active fusion protein, active fragment, or molecular mimic, that binds to BMP-4 transmembrane receptors on melanocytes and decreases the level of melanin synthesis. Also described are methods to identify molecules that mimic the function of BMP-4 in causing a decrease in melanin in melanocytes.

Methods For Lightening Skin And Hair

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US Patent:
20050152860, Jul 14, 2005
Filed:
Oct 12, 2004
Appl. No.:
10/963432
Inventors:
Mina Yaar - Sharon MA, US
Hee-Young Park - Weston MA, US
Vladimir Botchkarev - Sharon MA, US
Barbara Gilchrest - Boston MA, US
Assignee:
Trustees of Boston University - Boston MA
International Classification:
A61K007/135
A61K009/127
A61K038/17
US Classification:
424062000, 514012000, 424450000
Abstract:
Methods are described wherein the skin of a vertebrate, or the skin or hair of a mammal can be lightened by administration of an agent, e.g., protein, peptide, active fusion protein, active fragment, or molecular mimic, that binds to BMP-4 transmembrane receptors on melanocytes and decreases the level of melanin synthesis. Also described are methods to identify molecules that mimic the function of BMP-4 in causing a decrease in melanin in melanocytes.
Vladimir V Botchkarev from Brookline, MA, age ~35 Get Report