Inventors:
Vivian Mak - Menlo Park CA
Assignee:
Adolor Corporation - Malvern PA
International Classification:
A61K 31445
Abstract:
The present invention provides a number of screening methods for evaluatiing compounds capable of suppressing cytokine production either in vitro or in vivo. The methods generally involve stimulating the production of a cytokine in a cell, exposing a portion of the cells to a putative cytokine modulating agent and determining subsequent levels of cytokine production in the cells. Additionally, the present invention provides certain compounds identified by this method.
