Inventors:
David J. Ecker - Encinitas CA, US
Richard H. Griffey - Vista CA, US
Rangarajan Sampath - San Diego CA, US
Stephen A. Hofstadler - Vista CA, US
John McNeil - La Jolla CA, US
Stanley T. Crooke - Carlsbad CA, US
Lawrence B. Blyn - Mission Viejo CA, US
Thomas A. Hall - Oceanside CA, US
Yun Jiang - Carlsbad CA, US
James C. Hannis - Vista CA, US
Neill White - Vista CA, US
Vivek Samant - Encinitas CA, US
Mark W. Eshoo - Solana Beach CA, US
Jared J. Drader - Carlsbad CA, US
Assignee:
Ibis Biosciences, Inc. - Carlsbad CA
International Classification:
C12Q 1/68
C12P 19/34
C07H 21/04
US Classification:
435 612, 435 912, 536 2433
Abstract:
The present invention provides methods for rapid forensic analysis of mitochondrial DNA and methods for characterizing heteroplasmy of mitochondrial DNA, which can be used to assess the progression of mitochondrial diseases.