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Virender M Labroo

from Bothell, WA
Age ~72

Virender Labroo Phones & Addresses

  • 2814 163Rd St, Mill Creek, WA 98012
  • Bothell, WA
  • Mountlake Terrace, WA

Resumes

Resumes

Virender Labroo Photo 1

Owner At Labroo Financial Group, Llc Owner At Pharmaceutical Discovery Associates (Sole Proprietorship)

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Location:
Greater Seattle Area
Industry:
Research
Experience:
Labroo Financial Group, LLC (Privately Held; Myself Only; Internet industry): Owner,  (June 2007-Present) Pharmaceutical Discovery Associates (Sole Proprietorship) (Sole Proprietorship; Myself Only; Pharmaceuticals industry): Owner,  (November 199...
Virender Labroo Photo 2

Virender Labroo

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Publications

Us Patents

Motilin Homologs

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US Patent:
6838438, Jan 4, 2005
Filed:
Feb 27, 2001
Appl. No.:
09/794987
Inventors:
Paul O. Sheppard - Granite Falls WA, US
Theresa A. Deisher - Seattle WA, US
Paul D. Bishop - Fall City WA, US
Stephen R. Jaspers - Edmonds WA, US
Virender M. Labroo - Mill Creek WA, US
Assignee:
ZymoGenetics, Inc. - Seattle WA
International Classification:
A61K 3810
C07K 708
C07K 1463
US Classification:
514 13, 514 14, 530326, 530327
Abstract:
The present invention is directed to polynucleotides, polypeptides and peptide fragments thereof, and uses thereof for a novel cDNA sequence which has homology to motilin. Tissue distribution of the mRNA for the novel polypeptide is specific to the stomach, small intestine and pancreas. The present invention further includes agonists, antagonists, antibodies, host cells expressing the cDNA encoding the novel motilin homologs and methods for increasing gastric motility using the novel molecules.

Polynucleotides Encoding Motilin Homologs

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US Patent:
6939690, Sep 6, 2005
Filed:
Feb 28, 2001
Appl. No.:
09/796158
Inventors:
Paul O. Sheppard - Granite Falls WA, US
Theresa A. Deisher - Seattle WA, US
Paul D. Bishop - Fall City WA, US
Stephen R. Jaspers - Edmonds WA, US
Virender M. Labroo - Mill Creek WA, US
Assignee:
ZymoGenetics, Inc. - Seattle WA
International Classification:
C12P021/02
C12N005/10
C12N001/21
C12N015/63
C12N015/16
US Classification:
435 694, 4353201, 435325, 4352523, 536 2351, 536 241, 530326, 530327, 530324
Abstract:
The present invention is directed to polynucleotides, polypeptides and peptide fragments thereof, and uses thereof for a novel cDNA sequence which has homology to motilin. Tissue distribution of the mRNA for the novel polypeptide is specific to the stomach, small intestine and pancreas. The present invention further includes agonists, antagonists, antibodies, host cells expressing the cDNA encoding the novel motilin homologs and methods for increasing gastric motility using the novel molecules.

Methods Of Using Motilin Homologs

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US Patent:
7977309, Jul 12, 2011
Filed:
Mar 13, 2008
Appl. No.:
12/075821
Inventors:
Paul O. Sheppard - Granite Falls WA, US
Theresa A. Deisher - Seattle WA, US
Paul D. Bishop - Fall City WA, US
Stephen R. Jaspers - Edmonds WA, US
Virender M. Labroo - Mill Creek WA, US
Assignee:
Zymogenetics - Seattle WA
International Classification:
A61K 38/10
C07K 14/63
US Classification:
514 49, 530327
Abstract:
The present invention is directed to polynucleotides, polypeptides and peptide fragments thereof, and uses thereof for a novel cDNA sequence which has homology to motilin. Tissue distribution of the mRNA for the novel polypeptide is specific to the stomach, small intestine and pancreas. The present invention further includes agonists, antagonists, antibodies, host cells expressing the cDNA encoding the novel motilin homologs and methods for increasing gastric motility using the novel molecules.

Antibodies To Motilin Homologs

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US Patent:
20050106146, May 19, 2005
Filed:
Aug 25, 2004
Appl. No.:
10/927484
Inventors:
Paul Sheppard - Granite Falls WA, US
Theresa Deisher - Seattle WA, US
Paul Bishop - Fall City WA, US
Stephen Jaspers - Edmonds WA, US
Virender Labroo - Mill Creek WA, US
International Classification:
A61K039/395
C07K016/26
US Classification:
424145100, 530388250
Abstract:
The present invention is directed to polynucleotides, polypeptides and peptide fragments thereof, and uses thereof for a novel cDNA sequence which has homology to motilin. Tissue distribution of the mRNA for the novel polypeptide is specific to the stomach, small intestine and pancreas. The present invention further includes agonists, antagonists, antibodies, host cells expressing the cDNA encoding the novel motilin homologs and methods for increasing gastric motility using the novel molecules.

Method For Inhibiting The Stimulation Of A Glucagon-Induced Response Pathway In A Warm-Blooded Animal In Need Thereof

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US Patent:
56773340, Oct 14, 1997
Filed:
Sep 11, 1995
Appl. No.:
8/526722
Inventors:
Robert R. West - Seattle WA
Virender Labroo - Mill Creek WA
James R. Piggott - Bothell WA
Robert A. Smith - Seattle WA
Patricia A. McKernan - Woodinville WA
Assignee:
ZymoGenetics, Inc. - Seattle WA
International Classification:
A61K 3121
US Classification:
514510
Abstract:
Glucagon antagonists and methods relating thereto are disclosed. The glucagon antagonists include skyrin and skyrin analogs, and serve to inhibit the stimulation of a glucagon-induced response pathway, such as the adenylate cyclase response pathway or the inositol phosphate response pathway. The glucagon antagonists may be used within therapeutic compositions to treat disease states associate with elevated glucose levels, including diabetes and hyperglycemia. The present invention also discloses a biologically pure culture of ATCC accession number 74200, as well as methods relating to the production of glucagon antagonists by cultivating the same in a nutrient medium and recovering the glucagon antagonist therefrom.

Method For Inhibiting Bone Loss Using Centchroman Derivatives

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US Patent:
54648629, Nov 7, 1995
Filed:
Jan 13, 1994
Appl. No.:
8/180728
Inventors:
Virender M. Labroo - Mill Creek WA
James R. Piggott - Bothell WA
Steven D. Bain - Seattle WA
Assignee:
ZymoGenetics, Inc. - Seattle WA
International Classification:
A61K 3140
US Classification:
514422
Abstract:
Methods and pharmaceutical compositions for reducing bone loss are disclosed. 3,4-diarylchromans and their pharmaceutically acceptable salts are formulated into medicaments for the treatment of bone loss due to osteoporosis or other conditions. An exemplary 3,4-diarylchroman is centchroman (3,4-trans-2,2-dimethyl-3-phenyl-4-[p-(beta-pyrrolidinoethoxy)phenyl]-7-me thoxychroman). Formulations include tablets and other forms suitable for oral administration and controlled-release subdermal implants.

Method For Treating Dermatitis And Related Conditions

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US Patent:
54160987, May 16, 1995
Filed:
Dec 30, 1993
Appl. No.:
8/175840
Inventors:
Virender M. Labroo - Mill Creek WA
James R. Piggott - Bothell WA
Assignee:
ZymoGenetics, Inc. - Seattle WA
International Classification:
A61K 31395
A61K 3155
A61K 31445
A61K 3140
US Classification:
514320
Abstract:
Methods and pharmaceutical compositions for the treatment of dermatitis are disclosed. 2,3-diaryl-1-benzopyrans and their pharmaceutically acceptable salts are formulated into medicaments, including oral and topical medicaments, which are administered to a patient suffering from dermatitis. The methods and compositions are particularly useful in the treatment of conditions characterized by hyperproliferation of keratinocytes, such as psoriasis.

Combinatorial Non-Peptide Libraries

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US Patent:
58917373, Apr 6, 1999
Filed:
Jun 7, 1995
Appl. No.:
8/482231
Inventors:
Nand Baindur - Edmonds WA
Virender M. Labroo - Mill Creek WA
Assignee:
ZymoGenetics, Inc. - Seattle WA
International Classification:
G01N 33543
US Classification:
436518
Abstract:
Predetermined combinatorial libraries of non-peptide compounds are disclosed. Compounds useful for generating such libraries are also disclosed.
Virender M Labroo from Bothell, WA, age ~72 Get Report