Inventors:
Vinata B. Lokeshwar - Miami FL, 33176
Henry T. Pham - Houston TX, 77081
International Classification:
C12Q 100
US Classification:
435 4, 435 71, 435 74, 435 772, 435810, 436 64
Abstract:
The present invention relates to novel methods for detecting and evaluating bladder cancer. The methods of the present invention are based on the discovery that normalized amounts of hyaluronic acid (HA) and hyaluronidase (HAase) are diagnostic markers for the detection of bladder cancer, evaluation of its grade, monitoring of the efficacy of its treatment, and tumor recurrence.