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Viktor S Goldmakher

from Newton Center, MA
Age ~71
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Also known as:
Vktor S Goldmakher, Victor S Goldmakher, Viktor S Goldmaker
Phone and address:
74 Pelham St, Newton, MA 02459
(617) 527-7168
Related to:
Hiroko Araya Schafer, 61
Connected to:
Alla Goldman, 52Alyssa Goldman, 60Annelise Goldman, 39Arce M Goldman, 51Ariane Goldman, 46Arleen P Goldman, 76Artem Goldman, 49Arthur Goldman, 64Bella G Goldman, 98Bernice T Goldman, 96

Viktor Goldmakher Phones & Addresses

  • 74 Pelham St, Newton Center, MA 02459 (617) 527-7168
  • Newton, MA
  • Warrington, PA
  • Philadelphia, PA
  • 74 Pelham St, Newton Center, MA 02459

Work

Position: Service Occupations

Publications

Us Patents

Compounds, Methods Of Screening, And In Vitro And In Vivo Uses Involving Anti-Apoptotic Genes And Anti-Apoptotic Gene Products

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US Patent:
6605426, Aug 12, 2003
Filed:
Nov 21, 2000
Appl. No.:
09/716504
Inventors:
Viktor S. Goldmakher - Newton MA
Anna Skaletskaya - Milton MA
Laura M. Bartle - Arlington MA
Assignee:
Apoptosis Technology, Inc. - Cambridge MA
International Classification:
C12Q 170
US Classification:
435 5, 435 6, 435 71, 435 721
Abstract:
Novel polypeptides having anti-apoptotic activity, and methods of screening for such novel polypeptides having anti-apoptotic activity, and polynucleotides encoding such polypeptides; Compounds that regulate or modulate apoptosis and/or anti-apoptotic activity, such as compounds having anti-apoptotic activity, and such as compounds that induce, restore, or modulate apoptosis and/or inhibit, diminish, or modulate anti-apoptotic activity, methods of screening for such compounds, and methods of using such compounds in the therapeutic treatment of diseases; Methods of treating eukaryotic cells with compounds that regulate or modulate apoptosis and/or anti-apoptotic activity; Methods of enhancing the stability, growth, and/or productivity of eukaryotic cells; Pharmaceutical compositions that regulate or modulate apoptosis and/or anti-apoptotic activity.

Compounds, Methods Of Screening, And In Vitro And In Vivo Uses Involving Anti-Apoptotic Genes And Anti-Apoptotic Gene Products

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US Patent:
6902885, Jun 7, 2005
Filed:
Jun 18, 2003
Appl. No.:
10/463756
Inventors:
Viktor S. Goldmakher - Newton MA, US
Anna Skaletskaya - Milton MA, US
Laura M. Bartle - Arlington MA, US
Assignee:
Apoptosis Technology, Inc. - Cambridge MA
International Classification:
C12Q001/70
US Classification:
435 5, 435 6, 435 71, 435 721
Abstract:
Novel polypeptides having anti-apoptotic activity, and methods of screening for such novel polypeptides having anti-apoptotic activity, and polynucleotides encoding such polypeptides; Compounds that regulate or modulate apoptosis and/or anti-apoptotic activity, such as compounds having anti-apoptotic activity, and such as compounds that induce, restore, or modulate apoptosis and/or inhibit, diminish, or modulate anti-apoptotic activity, methods of screening for such compounds, and methods of using such compounds in the therapeutic treatment of diseases; Methods of treating eukaryotic cells with compounds that regulate or modulate apoptosis and/or anti-apoptotic activity; Methods of enhancing the stability, growth, and/or productivity of eukaryotic cells; Pharmaceutical compositions that regulate or modulate apoptosis and/or anti-apoptotic activity.

Antibodies To Non-Shed Muc1 And Muc16, And Uses Thereof

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US Patent:
7202346, Apr 10, 2007
Filed:
Jul 3, 2003
Appl. No.:
10/612090
Inventors:
Gillian Payne - Waban MA, US
Thomas Chittenden - Sudbury MA, US
Viktor Goldmakher - Newton MA, US
Philip Chun - Malden MA, US
Carol A. Vater - Cambridge MA, US
Assignee:
Immunogen Inc. - Cambridge MA
International Classification:
C07K 16/00
US Classification:
5303881, 5303873, 530350, 530380, 530385, 5303871, 5303877, 4241341, 4241351, 4241411, 4241551, 4241421, 4241781, 424 851, 435 79, 435188, 4353201, 525 541
Abstract:
The present invention relates to antibodies, antibody fragments, conjugates of antibodies and antibody fragments with cytotoxic agents, and hybridomas producing the antibodies and antibody fragments, where the antibodies and antibody fragments recognize extracellular epitopes of plasma membrane proteins that are not released into the extracellular fluid, and to methods for the detection, monitoring and treatment of malignancies such as breast cancer and ovarian cancer using the antibodies, antibody fragments and conjugates.

Compounds, Methods Of Screening, And In Vitro And In Vivo Uses Involving Anti-Apoptotic Genes And Anti-Apoptotic Gene Products

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US Patent:
7449450, Nov 11, 2008
Filed:
Apr 13, 2005
Appl. No.:
11/104506
Inventors:
Viktor S Goldmakher - Newton MA, US
Anna Skaletskaya - Milton MA, US
Laura M Bartle - Arlington MA, US
Assignee:
Immunogen Inc. - Waltham MA
International Classification:
A61K 31/7088
A61K 31/7125
US Classification:
514 44, 536 2372, 536 245
Abstract:
Novel polypeptides having anti-apoptotic activity, and methods of screening for such novel polypeptides having anti-apoptotic activity, and polynucleotides encoding such polypeptides; Compounds that regulate or modulate apoptosis and/or anti-apoptotic activity, such as compounds having anti-apoptotic activity, and such as compounds that induce, restore, or modulate apoptosis and/or inhibit, diminish, or modulate anti-apoptotic activity, methods of screening for such compounds, and methods of using such compounds in the therapeutic treatment of diseases; Methods of treating eukaryotic cells with compounds that regulate or modulate apoptosis and/or anti-apoptotic activity; Methods of enhancing the stability, growth, and/or productivity of eukaryotic cells; Pharmaceutical compositions that regulate or modulate apoptosis and/or anti-apoptotic activity.

Elimination Of Heterogeneous Or Mixed Cell Population In Tumors

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US Patent:
8137669, Mar 20, 2012
Filed:
Aug 5, 2008
Appl. No.:
12/186411
Inventors:
Viktor S. Goldmakher - Newton MA, US
Robert J. Lutz - Wayland MA, US
Ravi V. J. Chari - Newton MA, US
Yelena V. Kovtun - Maynard MA, US
John M. Lambert - Cambridge MA, US
Rita Steeves - Stoneham MA, US
Hans K. Erickson - Cambridge MA, US
Assignee:
Immunogen, Inc. - Waltham MA
International Classification:
A61K 39/00
US Classification:
4241331
Abstract:
Methods of killing or inhibiting tumors comprising of heterogeneous or mixed cell populations is described. The killing or inhibition of tumors is achieved by selectively targeting a unique ligand suspected of being expressed on a particular cell population to also kill a cell population lacking the unique ligand. These conjugates have therapeutic use as they are delivered to a specific cell population to kill these cells and the cytotoxic drug is released to kill non-targeted cells, thereby eliminating the tumor.

Elimination Of Heterogeneous Or Mixed Cell Population In Tumors

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US Patent:
8388960, Mar 5, 2013
Filed:
Sep 9, 2011
Appl. No.:
13/229422
Inventors:
Viktor S. Goldmakher - Newton MA, US
Robert J. Lutz - Wayland MA, US
Ravi V. J. Chari - Newton MA, US
Yelena V. Kovtun - Stow MA, US
John M. Lambert - Cambridge MA, US
Rita Steeves - Stoneham MA, US
Hans K. Erickson - Belmont MA, US
Wayne C. Widdison - Belmont MA, US
Assignee:
Immunogen Inc. - Waltham MA
International Classification:
A61K 39/00
US Classification:
4241331
Abstract:
Methods of killing or inhibiting tumors comprising of heterogeneous or mixed cell populations is described. The killing or inhibition of tumors is achieved by selectively targeting a unique ligand suspected of being expressed on a particular cell population to also kill a cell population lacking the unique ligand. These conjugates have therapeutic use as they are delivered to a specific cell population to kill these cells and the cytotoxic drug is released to kill non-targeted cells, thereby eliminating the tumor.

Folate Receptor 1 Antibodies And Immunoconjugates And Uses Thereof

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US Patent:
8557966, Oct 15, 2013
Filed:
Feb 24, 2011
Appl. No.:
13/033723
Inventors:
Olga Ab - Millis MA, US
Daniel Tavares - Natick MA, US
Lingyun Rui - Weston MA, US
Gillian Payne - Waban MA, US
Viktor S. Goldmakher - Newton MA, US
Assignee:
ImmunoGen, Inc. - Waltham MA
International Classification:
C07K 16/00
C12P 21/08
US Classification:
5303871, 5303873, 5303911, 5303917
Abstract:
Novel anti-cancer agents, including, but not limited to, antibodies and immunoconjugates, that bind to human folate receptor 1 are provided. Methods of using the agents, antibodies, or immunoconjugates, such as methods of inhibiting tumor growth are further provided.

Compounds, Methods Of Screening, And In Vitro And In Vivo Uses Involving Anti-Apoptotic Genes And Anti-Apoptotic Gene Products

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US Patent:
20030198949, Oct 23, 2003
Filed:
Jun 18, 2003
Appl. No.:
10/463808
Inventors:
Viktor Goldmakher - Newton MA, US
Anna Skaletskaya - Milton MA, US
Laura Bartle - Arlington MA, US
Assignee:
APOPTOSIS TECHNOLOGY, INC.
International Classification:
C12Q001/70
C12N007/00
A61K048/00
A61K038/16
US Classification:
435/005000, 435/235100, 514/012000, 514/044000
Abstract:
Novel polypeptides having anti-apoptotic activity, and methods of screening for such novel polypeptides having anti-apoptotic activity, and polynucleotides encoding such polypeptides; Compounds that regulate or modulate apoptosis and/or anti-apoptotic activity, such as compounds having anti-apoptotic activity, and such as compounds that induce, restore, or modulate apoptosis and/or inhibit, diminish, or modulate anti-apoptotic activity, methods of screening for such compounds, and methods of using such compounds in the therapeutic treatment of diseases; Methods of treating eukaryotic cells with compounds that regulate or modulate apoptosis and/or anti-apoptotic activity; Methods of enhancing the stability, growth, and/or productivity of eukaryotic cells; Pharmaceutical compositions that regulate or modulate apoptosis and/or anti-apoptotic activity.
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Viktor S Goldmakher from Newton Center, MA, age ~71 Get Report