Inventors:
- San Diego CA, US
Adrian Chrastina - Chula Vista CA, US
Veronique Therese Baron - Carlsbad CA, US
Parisa Abedinpour - San Diego CA, US
International Classification:
C07C 323/61
A61K 31/122
C07C 233/25
A61K 31/167
C07C 217/60
A61K 31/137
C07C 205/36
C07C 69/92
A61K 31/235
C07C 271/46
A61K 31/325
C07C 225/30
A61K 31/135
A61K 31/136
C07C 311/51
A61K 31/18
C07C 311/16
C07C 233/23
A61K 31/165
C07C 69/63
A61K 31/222
A61K 31/573
A61K 31/58
A61K 31/56
A61K 31/4166
A61K 31/277
A61K 31/05
A61K 31/661
A61K 31/496
A61K 31/45
A61K 31/4164
C07C 50/32
Abstract:
Disclosed herein are 1,4-naphthoquinone analogs, pharmaceutical compositions that include one or more of such 1,4-naphthoquinone analogs, and methods of treating and/or ameliorating diseases and/or conditions associated with a cancer, such as prostate cancer with such 1,4-naphthoquinone analogs. Also included are combination therapies wherein a 1,4-naphthoquinone analog disclosed herein, and a hormone therapy agent are provided to a subject suffering from a condition such as cancer.