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Valentino J Stella

from Lawrence, KS
Age ~78
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Also known as:
Valenti J Stella, Stella Valentino
Phone and address:
1135 Campus Rd, Lawrence, KS 66044
(785) 843-8807
Related to:
C Huebner, 43Elise Stella, 37Anne Stella, 40Cathy Stella, 78M Elizabeth Stella, 77Gregory W Huebner, 44Catherine S Huebner, 43
Connected to:
Alfredo Stella, 52Amparo D Stella, 84Becky L Stella, 54Brenda S Stella, 58Christina M Stella, 46Colby A Stellabott, 53Cosimo Stella, 104Gaetano Stellacci, 78Grace E Stella, 79Jennifer Stella, 40

Valentino Stella Phones & Addresses

  • 1135 Campus Rd, Laurence, KS 66044 (785) 843-8807
  • 1324 Lawrence Ave, Laurence, KS 66049 (785) 843-8807
  • Lawrence, KS
  • La Jolla, CA

Work

Company: The university of kansas Position: University distinguished professor

Education

Degree: Doctorates, Doctor of Philosophy School / High School: The University of Kansas 1967 to 1971 Specialities: Philosophy, Chemistry

Industries

Pharmaceuticals

Public records

Vehicle Records

Valentino Stella

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Address:
1135 W Campus Rd, Lawrence, KS 66044
Phone:
(785) 843-8807
VIN:
JTJBC1BA9A2028703
Make:
LEXUS
Model:
RX 450H
Year:
2010

Resumes

Resumes

Valentino Stella Photo 1

University Distinguished Professor At The University Of Kansas

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Location:
1603 west 15Th St, Lawrence, KS 66044
Industry:
Pharmaceuticals
Work:
The University of Kansas
University Distinguished Professor
Education:
The University of Kansas 1967 - 1971
Doctorates, Doctor of Philosophy, Philosophy, Chemistry Victorian College of Pharmacy, Now Monash 1964 - 1967
Bachelors, Bachelor of Pharmacy, Pharmacy

Publications

Us Patents

Water Soluble Prodrugs Of Hindered Alcohols

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US Patent:
6451776, Sep 17, 2002
Filed:
Dec 8, 2000
Appl. No.:
09/733817
Inventors:
Valentino J. Stella - Lawrence KS
Jan J. Zygmunt - Longmont CO
Ingrid Gunda Georg - Lawrence KS
Muhammad S. Safadi - Nazareth, IL
Assignee:
University of Kansas - Lawrence KS
International Classification:
A61K 31675
US Classification:
514 81, 546 24, 546 23, 562 8, 562 15, 514283, 514119, 514 75
Abstract:
The present invention is directed to novel water-soluble prodrugs of aliphatic or aromatic hindered hydroxyl group containing pharmaceuticals.

Antiviral Phosphonomethoxy Nucleotide Analogs Having Increased Oral Bioavailability

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US Patent:
RE38333, Nov 25, 2003
Filed:
May 29, 2002
Appl. No.:
10/159888
Inventors:
Murty N. Arimilli - Fremont CA
Kenneth C. Cundy - Belmont CA
Joseph P. Dougherty - New York NY
Choung U. Kim - San Carlos CA
Reza Oliyai - Foster City CA
Valentino J. Stella - Lawrence KS
Assignee:
Gilead Sciences, Inc. - Foster City CA
International Classification:
C07F 96512
US Classification:
544243, 544244, 546 23
Abstract:
Novel compounds are provided that comprise esters of antiviral phosphonomethoxy nucleotide analogs with carbonates and/or carbamates having the structure âOC(R ) OC(O)X(R) , wherein R independently is H, C -C alkyl, aryl, alkenyl, alkynyl, alkyenylaryl, alkynylaryl, alkaryl, arylalkynyl, arylalkenyl or arylalkyl which is unsubstituted or is substituted with halo, azido, nitro or OR in which R is C -C alkyl; X is N or O; R is independently H, C -C alkyl, aryl, alkenyl, alkynyl, alkyenylaryl, alkynylaryl, alkaryl, arylalkynyl, arylalkenyl or arylalkyl which is unsubstituted or is substituted with halo, azido, nitro, âOâ, âN , âNR â, âN(R ) â or OR , R independently is âH or C -C alkyl, provided that at least one R is not H; and a is 1 or 2, with the proviso that when a is 2 and X is N, (a) two R groups can be taken together to form a carbocycle or oxygen-containing heterocycle, or (b) one R additionally can be OR. The compounds are useful as intermediates for the preparation of antiviral compounds or oligonucleotides, or are useful for administration directly to patients for antiviral therapy of prophylaxis. Embodiments are particularly useful when administered orally.

Water Soluble Prodrugs Of Hindered Alcohols

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US Patent:
6872838, Mar 29, 2005
Filed:
Jul 29, 2002
Appl. No.:
10/208647
Inventors:
Valentino J. Stella - Lawrence KS, US
Jan J. Zygmunt - Longmont CO, US
Ingrid Gunda Georg - Lawrence KS, US
Muhammad S. Safadi - Nazareth, IL
Assignee:
University of Kansas - Lawrence KS
International Classification:
C07D493/02
C07F009/06
US Classification:
549220, 558187, 558177, 549298, 549408
Abstract:
The present invention is directed to novel water-soluble prodrugs of aliphatic or aromatic hindered hydroxyl group containing pharmaceuticals.

Water Soluble Prodrugs Of Hindered Alcohols

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US Patent:
7244718, Jul 17, 2007
Filed:
Nov 17, 2004
Appl. No.:
10/991348
Inventors:
Valentino J. Stella - Lawrence KS, US
Jan J. Zygmunt - Longmont CO, US
Ingrid Gunda Georg - Lawrence KS, US
Muhammad S. Safadi - Nazareth, IL
Assignee:
University of Kansas - Lawrence KS
International Classification:
A61K 31/661
A61K 31/66
US Classification:
514143, 514 75, 514130, 514816
Abstract:
The present invention is directed to novel water-soluble prodrugs of aliphatic or aromatic hindered hydroxyl group containing pharmaceuticals.

Prodrugs Of 2,4-Pyrimidinediamine Compounds And Their Uses

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US Patent:
7449458, Nov 11, 2008
Filed:
Jan 19, 2006
Appl. No.:
11/337049
Inventors:
Somasekhar Bhamidipati - Foster City CA, US
Rajinder Singh - Belmont CA, US
Valentino J. Stella - Lawrence KS, US
Thomas Sun - Fremont CA, US
Assignee:
Rigel Pharmaceuticals, Inc. - South San Francisco CA
International Classification:
C07D 498/04
A61K 31/5383
US Classification:
5142305, 544105
Abstract:
The present disclosure provides prodrugs of biologically active 2,4-pyrimidinediamine compounds of structural formula shown below, compositions comprising these compounds, intermediates and methods for synthesizing these compounds, and methods for using these compounds in a variety of applications including treatment of autoimmune diseases.

Prodrugs Of 2,4-Pyrimidinediamine Compounds And Their Uses

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US Patent:
7538108, May 26, 2009
Filed:
Jun 14, 2006
Appl. No.:
11/453731
Inventors:
Rajinder Singh - Belmont CA, US
Esteban Masuda - Menlo Park CA, US
Somasekhar Bhamidipati - Foster City CA, US
Thomas Sun - Palo Alto CA, US
Valentino J. Stella - Lawrence KS, US
Assignee:
Rigel Pharmaceuticals, Inc. - South San Francisco CA
International Classification:
C07D 498/04
A61K 31/5383
US Classification:
5142305, 544105
Abstract:
The present disclosure provides prodrugs of biologically active 2,4-pyrimidinediamine compounds of structural formula shown below, compositions comprising these compounds, intermediates and methods for synthesizing these compounds, and methods of using these compounds in a variety of applications including treatment of autoimmune diseases.

Prodrugs Of 2,4 Pyrimidinediamine Compounds And Their Uses

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US Patent:
7563892, Jul 21, 2009
Filed:
Oct 5, 2006
Appl. No.:
11/539074
Inventors:
Rajinder Singh - Belmont CA, US
Somasekhar Bhamidipati - Foster City CA, US
Valentino J. Stella - Lawrence KS, US
Thomas Sun - Fremont CA, US
Assignee:
Rigel Pharmaceuticals, Inc. - South San Francisco CA
International Classification:
C07D 498/04
A61K 31/5383
US Classification:
544105, 5142305
Abstract:
The present disclosure provides the 2,4-pyrimidinediamine compound shown below, compositions comprising the compound, intermediates and methods for synthesizing the compound, and methods of using the compound in a variety of applications including treatment of autoimmune diseases.

Sulfoalkyl Ether-Alkyl Ether Cyclodextrin Derivatives

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US Patent:
7625878, Dec 1, 2009
Filed:
Apr 28, 2006
Appl. No.:
11/413597
Inventors:
Valentino J. Stella - Lawrence KS, US
Serena Tongiani - Lawrence KS, US
Assignee:
The University of Kansas - Lawrence KS
International Classification:
A61K 31/724
US Classification:
514 58, 536103
Abstract:
A sulfoalkyl ether-alkyl ether cyclodextrin (SAE-AE-CD) derivative is provided. The SAE-AE-CD possesses advantages over known SAE-CD and AE-CD derivatives as well as over the parent cyclodextrin by being more water soluble and less membrane disturbing. The SAE-AE-CD includes at least one sulfoalkyl ether group and at least one alkyl ether group even though the degree of substitution for the functional groups can be different. The SAE functional group can be present in molar excess over the AE functional group and vice versa. The total degree of substitution of the cyclodextrin, with respect to both functional groups, can be varied such that a minority or a majority of the hydroxyl moieties of the CD are derivatized. The SAE-AE-CD derivative can be used to solubilize compounds with insufficient water solubility. In some cases, they also stabilize compounds in solution against degradation or to solubilize degradation products formed during degradation.

Isbn (Books And Publications)

Stability of Drugs and Dosage Forms

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Author

Valentino J. Stella

ISBN #

0306464047

Pro-Drugs as Novel Drug Delivery Systems: A Symposium

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Author

Valentino J. Stella

ISBN #

0841202915

Lymphatic Transport of Drugs

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Author

Valentino J. Stella

ISBN #

0849363942

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Valentino J Stella from Lawrence, KS, age ~78 Get Report