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Vaithianathan Palaniappan

from Andover, MA

Vaithianathan Palaniappan Phones & Addresses

  • 7 Spruce Cir, Andover, MA 01810
  • 22 Elysian Dr, Andover, MA 01810 (978) 474-0512
  • Riverside, CA
  • Waltham, MA
  • Chino Hills, CA
  • Cambridge, MA
  • Diamond Bar, CA
  • Garnerville, NY
  • 7 Spruce Cir, Andover, MA 01810 (978) 474-0512

Work

Position: Precision Production Occupations

Education

Degree: Associate degree or higher

Publications

Us Patents

Boronate Ester Compounds And Pharmaceutical Compositions Thereof

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US Patent:
20130165390, Jun 27, 2013
Filed:
Nov 2, 2012
Appl. No.:
13/667164
Inventors:
Millennium Pharmaceuticals, Inc. - Cambridge MA, US
Abu J. Ferdous - Winchester MA, US
Michael J. Kaufman - Lexington MA, US
Sonja A. Komar - Belmont MA, US
Debra L. Mazaik - Hopkinton MA, US
Quentin J. McCubbin - Belmont MA, US
Phuong M. Nguyen - Cambridge MA, US
Vaithianathan Palaniappan - Andover MA, US
Raymond D. Skwierczynski - Andover MA, US
Nobel T. Truong - Milford MA, US
Csanad M. Varga - Cambridge MA, US
Peter N. Zawaneh - Cambridge MA, US
Assignee:
MILLENNIUM PHARMACEUTICALS, INC. - Cambridge MA
International Classification:
C07K 5/06
US Classification:
514 193, 558288, 544229, 546 13
Abstract:
The present invention provides novel compounds useful as proteasome inhibitors. The invention also provides pharmaceutical compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various diseases.

Boronate Ester Compounds And Pharmaceutical Compositions Thereof

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US Patent:
20090325903, Dec 31, 2009
Filed:
Jun 16, 2009
Appl. No.:
12/485344
Inventors:
Eric L. Elliott - Brighton MA, US
Abu J. Ferdous - Winchester MA, US
Michael J. Kaufman - Lexington MA, US
Sonja A. Komar - Belmont MA, US
Debra L. Mazaik - Hopkinton MA, US
Quentin J. McCubbin - Belmont MA, US
Phuong Nguyen - Cambridge MA, US
Vaithianathan Palaniappan - Andover MA, US
Raymond D. Skwierczynski - Andover MA, US
Nobel T. Truong - Milford MA, US
Csanad M. Varga - Cambridge MA, US
Peter N. Zawaneh - Cambridge MA, US
Assignee:
Millennium Pharmaceuticals, Inc. - Cambridge MA
International Classification:
A61K 31/69
C07F 5/04
A61P 35/00
US Classification:
514 64, 558288, 544229
Abstract:
The present invention provides novel compounds useful as proteasome inhibitors. The invention also provides pharmaceutical compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various diseases.

Formulation For Anti-Alpha4Beta7 Antibody

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US Patent:
20220370617, Nov 24, 2022
Filed:
Feb 22, 2022
Appl. No.:
17/652090
Inventors:
- Cambridge MA, US
Nobel T. Truong - Milford MA, US
Csanad M. Varga - Cambridge MA, US
Vaithianathan Palaniappan - Andover MA, US
Jason Brown - Burlington MA, US
Irving H. Fox - Wellesley MA, US
Catherine Scholz - Woburn MA, US
International Classification:
A61K 47/26
A61K 9/00
A61K 9/19
C07K 16/28
A61K 39/395
A61K 47/18
Abstract:
Antibody formulations are described comprising a mixture of a non-reducing sugar, an anti-α4β7 antibody and at least one amino acid. The disclosed formulations have improved stability, reduced aggregate formation, and may retard degradation of the anti-α4β7 antibody therein or exhibit any combinations thereof. The present invention further provides a safe dosing regimen of these antibody formulations that is easy to follow, and which results in a therapeutically effective amount of the anti-α4β7 antibody in vivo.

Formulation For Anti-Alpha4Beta7 Antibody

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US Patent:
20210340261, Nov 4, 2021
Filed:
Apr 23, 2021
Appl. No.:
17/239512
Inventors:
- Cambridge MA, US
Phoung M. Nguyen - Cambridge MA, US
Csanad M. Varga - Newton MA, US
Vaithianathan Palaniappan - Andover MA, US
Jason Brown - Burlington MA, US
Irving H. Fox - Wellesley MA, US
Catherine Scholz - Woburn MA, US
Erica Helen Jenkins - Cambridgeshire, GB
Maria Rosario - Mystic CT, US
International Classification:
C07K 16/28
A61K 9/00
A61K 47/12
A61K 47/14
A61K 47/18
A61K 47/26
A61K 39/395
Abstract:
Antibody formulations are described comprising a mixture of an anti-α4β7 antibody, an antioxidant or chelator, and at least one free amino acid. The disclosed formulations may have improved stability, reduced aggregate formation, or both. The present invention further provides a safe dosing regimen of these antibody formulations that is easy to follow, and which results in a therapeutically effective amount of the anti-α4β7 antibody in vivo.

Formulation For Anti-Alpha4Beta7 Antibody

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US Patent:
20210052733, Feb 25, 2021
Filed:
Jan 15, 2020
Appl. No.:
16/743813
Inventors:
- Cambridge MA, US
Nobel T. Truong - Milford MA, US
Csanad M. Varga - Cambridge MA, US
Vaithianathan Palaniappan - Andover MA, US
Jason Brown - Burlington MA, US
Catherine Schloz - Woburn MA, US
International Classification:
A61K 47/26
A61K 9/00
A61K 9/19
C07K 16/28
A61K 39/395
A61K 47/18
Abstract:
Antibody formulations are described comprising a mixture of a non-reducing sugar, an anti-α4β7 antibody and at least one amino acid. The disclosed formulations have improved stability, reduced aggregate formation, and may retard degradation of the anti-α4β7 antibody therein or exhibit any combinations thereof. The present invention further provides a safe dosing regimen of these antibody formulations that is easy to follow, and which results in a therapeutically effective amount of the anti-α4β7 antibody in vivo.

Boronate Ester Compounds And Pharmaceutical Compositions Thereof

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US Patent:
20200392164, Dec 17, 2020
Filed:
Sep 1, 2020
Appl. No.:
17/009199
Inventors:
- Cambridge MA, US
Abu J. Ferdous - Nottingham MD, US
Michael J. Kaufman - Lexington MA, US
Debra L. Mazaik - Holliston MA, US
Quentin J. Mccubbin - Belmont MA, US
Phuong M. Nguyen - Cambridge MA, US
Vaithianathan Palaniappan - Andover MA, US
Raymond D. Skwierczynski - Andover MA, US
Nobel T. Truong - Milford MA, US
Csanad M. Varga - Newton MA, US
Peter N. Zawaneh - Brookline MA, US
International Classification:
C07F 5/04
C07K 5/078
C07F 5/02
C07K 5/06
C07C 233/83
A61K 31/198
A61K 31/454
A61K 31/69
Abstract:
The present invention provides novel compounds useful as proteasome inhibitors. The invention also provides pharmaceutical compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various diseases.

Formulation For Anti-Alpha4Beta7 Antibody

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US Patent:
20200377601, Dec 3, 2020
Filed:
Feb 11, 2020
Appl. No.:
16/787521
Inventors:
- Cambridge MA, US
Phoung M. Nguyen - Cambridge MA, US
Csanad M. Varga - Cambridge MA, US
Vaithianathan Palaniappan - Andover MA, US
Jason Brown - Burlington MA, US
Irving H. Fox - Wellesley MA, US
Catherine Scholz - Woburn MA, US
Erica Helen Jenkins - Cambridgeshire, GB
Maria Rosario - Mystic CT, US
International Classification:
C07K 16/28
A61K 9/00
A61K 47/12
A61K 47/14
A61K 47/18
A61K 47/26
A61K 39/395
Abstract:
Antibody formulations are described comprising a mixture of an anti-α4β7 antibody, an antioxidant or chelator, and at least one free amino acid. The disclosed formulations may have improved stability, reduced aggregate formation, or both. The present invention further provides a safe dosing regimen of these antibody formulations that is easy to follow, and which results in a therapeutically effective amount of the anti-α4β7 antibody in vivo.

Boronate Ester Compounds And Pharmaceutical Compositions Thereof

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US Patent:
20200247829, Aug 6, 2020
Filed:
Apr 24, 2020
Appl. No.:
16/857227
Inventors:
- Cambridge MA, US
Abu J. Ferdous - Nottingham MD, US
Michael J. Kaufman - Lexington MA, US
Debra L. Mazaik - Holliston MA, US
Quentin J. Mccubbin - Belmont MA, US
Phuong M. Nguyen - Cambridge MA, US
Vaithianathan Palaniappan - Andover MA, US
Raymond D. Skwierczynski - Andover MA, US
Nobel T. Truong - Milford MA, US
Csanad M. Varga - Newton MA, US
Peter N. Zawaneh - Brookline MA, US
International Classification:
C07F 5/04
C07K 5/06
A61K 31/69
A61K 31/454
C07F 5/02
C07K 5/078
C07C 233/83
A61K 31/198
Abstract:
The present invention provides novel compounds useful as proteasome inhibitors. The invention also provides pharmaceutical compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various diseases.
Vaithianathan Palaniappan from Andover, MA Get Report