Inventors:
Vidadi Yusibov - Havertown PA, US
Vadim Mett - Newark DE, US
Konstantin Musiychuk - Newark DE, US
Assignee:
Fraunhofer USA, Inc. - Plymouth MI
International Classification:
C12P 21/06
C12N 9/00
C12N 9/24
C12N 1/20
C12N 15/00
C07H 21/04
US Classification:
435200, 435 691, 435183, 4352523, 4353201, 536 232
Abstract:
Recombinant carrier molecules having amino acid sequences from thermostable enzymes and methods of use for expression, recovery and delivery of foreign sequences (peptides and polypeptides) produced in different systems (bacteria, yeast, DNA, cell cultures such as mammalian, plant, insect cell cultures, protoplast and whole plants in vitro or in vivo are provided. The recombinant carrier molecule using sequences from lichenase B(Lic B) were also made and used as part of carrier protein to express, recover and deliver a variety of target polypeptides of interest.