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Vadim Mett Phones & Addresses

  • Hartford, KY
  • East Aurora, NY
  • 60 Gaylord Ct, Elma, NY 14059
  • 115 Wedgewood Rd, Newark, DE 19711 (302) 737-7847
  • 1 Shetland Ct, Newark, DE 19711 (302) 737-7847
  • 5 Hopkins Ave, Glenolden, PA 19036 (610) 583-1814
  • Buffalo, NY
  • Philadelphia, PA

Publications

Us Patents

Influenza Antigens, Vaccine Compositions, And Related Methods

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US Patent:
8124103, Feb 28, 2012
Filed:
Feb 13, 2007
Appl. No.:
11/706573
Inventors:
Vidadi Yusibov - Havertown PA, US
Vadim Mett - Newark DE, US
Assignee:
Fraunhofer USA, Inc - Plymouth MI
International Classification:
A61K 39/145
A61K 39/12
A61K 39/295
A61K 39/00
C12P 21/04
C07H 21/04
US Classification:
4242101, 4241851, 4241921, 4242041, 4242011, 435 697, 536 234, 536 2372
Abstract:
The present invention relates to the intersection of the fields of immunology and protein engineering, and particularly to antigens and vaccines useful in prevention of infection by influenza virus. Provided are recombinant protein antigens, compositions, and methods for the production and use of such antigens and vaccine compositions.

Recombinant Carrier Molecule For Expression, Delivery And Purification Of Target Polypeptides

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US Patent:
8173408, May 8, 2012
Filed:
Nov 24, 2009
Appl. No.:
12/625129
Inventors:
Vidadi Yusibov - Havertown PA, US
Vadim Mett - Newark DE, US
Konstantin Musiychuk - Newark DE, US
Assignee:
Fraunhofer USA, Inc. - Plymouth MI
International Classification:
C12P 21/06
C12N 9/00
C12N 9/24
C12N 1/20
C12N 15/00
C07H 21/04
US Classification:
435200, 435 691, 435183, 4352523, 4353201, 536 232
Abstract:
Recombinant carrier molecules having amino acid sequences from thermostable enzymes and methods of use for expression, recovery and delivery of foreign sequences (peptides and polypeptides) produced in different systems (bacteria, yeast, DNA, cell cultures such as mammalian, plant, insect cell cultures, protoplast and whole plants in vitro or in vivo are provided. The recombinant carrier molecule using sequences from lichenase B(Lic B) were also made and used as part of carrier protein to express, recover and deliver a variety of target polypeptides of interest.

Recombinant Carrier Molecule For Expression, Delivery And Purification Of Target Polypeptides

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US Patent:
8591909, Nov 26, 2013
Filed:
Apr 12, 2012
Appl. No.:
13/445492
Inventors:
Vidadi Yusibov - Havertown PA, US
Vadim Mett - Newark DE, US
Konstantin Musiychuk - Newark DE, US
Assignee:
iBio, Inc. - Newark DE
International Classification:
A61K 39/02
C12P 21/06
C12N 9/00
C12N 9/24
C12N 1/20
C12N 15/00
C07H 21/04
US Classification:
4241901, 435 691, 435183, 435200, 4352523, 4353201, 536 232
Abstract:
Recombinant carrier molecules having amino acid sequences from thermostable enzymes and methods of use for expression, recovery and delivery of foreign sequences (peptides and polypeptides) produced in different systems (bacteria, yeast, DNA, cell cultures such as mammalian, plant, insect cell cultures, protoplast and whole plants in vitro or in vivo are provided. The recombinant carrier molecule using sequences from lichenase B (Lic B) were also made and used as part of carrier protein to express, recover and deliver a variety of target polypeptides of interest.

Expression Of Foreign Sequences In Plants Using Transactivation System

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US Patent:
20050114920, May 26, 2005
Filed:
Apr 26, 2004
Appl. No.:
10/832603
Inventors:
Vidadi Yusibov - Havertown PA, US
Anna Hull - West Grove PA, US
Vadim Mett - Newark DE, US
Marina Skarjinskaia - Newark DE, US
International Classification:
A01H001/00
C12N015/82
US Classification:
800280000, 800288000, 435468000
Abstract:
A transactivation system and method for producing a foreign polypeptide of interest in cells of a host plant is disclosed. The transactivation system has two components. It has genetically transformed cells of the host plant having integrated in their nuclear genome, an inactive or silenced foreign nucleic acid sequence, which is capable of encoding, upon its activation, the foreign polypeptide of interest; and a recombinant RNA viral vector capable of infecting the cells of the host plant and encoding therein a factor for activating or facilitating the expression of inactive or silenced foreign nucleic acid sequence.

Production Of Foreign Nucleic Acids And Polypeptides In Sprout Systems

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US Patent:
20060277634, Dec 7, 2006
Filed:
Feb 13, 2006
Appl. No.:
11/353905
Inventors:
Vidadi Yusibov - Havertown PA, US
Vadim Mett - Newark DE, US
Shailaja Rabindran - Newark DE, US
Moneim Shamloul - Newark DE, US
Burt Ensley - Sedona AZ, US
International Classification:
A01H 5/00
C12N 15/82
A61K 36/31
US Classification:
800288000, 800306000, 424755000
Abstract:
The present invention provides systems and methods for producing a nucleic acid or protein in transgenic sprouted seedlings or sprouted seedlings engineered to transiently express a nucleic acid or protein of interest. The sprouted seedlings of the invention are grown in a contained, regulatable environment, wherein expression of a pharmaceutically active protein is controlled by an exogenously inducible promoter or a viral promoter. The sprouted seedlings may be eaten live or preferably harvested live to preserve the maximal biological activity of the nucleic acid or protein.

Influenza Antibodies, Compositions, And Related Methods

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US Patent:
20080124272, May 29, 2008
Filed:
Feb 13, 2007
Appl. No.:
11/707257
Inventors:
Vidadi Yusibov - Havertown PA, US
Gene Palmer - New Castle DE, US
Vadim Mett - Newark DE, US
International Classification:
A61K 9/127
A61K 39/395
A61K 49/00
C07K 16/18
C12N 5/16
C07K 16/46
C07K 16/08
A61K 51/12
US Classification:
424 149, 4241411, 424450, 424 91, 435326, 435 5, 5303873, 5303881, 53038815
Abstract:
The present invention relates to the intersection of the fields of immunology and protein engineering, and particularly to antigens and vaccines useful in prevention of infection by influenza virus. Provided are recombinant protein antigens, compositions, and methods for the production and use of such antigens and vaccine compositions.

Hpv Antigens, Vaccine Compositions, And Related Methods

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US Patent:
20080279877, Nov 13, 2008
Filed:
Feb 13, 2007
Appl. No.:
11/706568
Inventors:
Vidadi Yusibov - Havertown PA, US
Vadim Mett - Newark DE, US
International Classification:
A61K 39/00
C12P 21/04
C12N 15/11
C12N 5/04
A01H 5/00
A61P 37/00
US Classification:
4241861, 4242041, 435 693, 536 2372, 435419, 800298
Abstract:
The present invention relates to the intersection of the fields of immunology and protein engineering, and particularly to antigens and vaccines useful in prevention of infection by human papilloma virus. Provided are recombinant protein antigens, compositions, and methods for the production and use of such antigens and vaccine compositions.

Compositions And Methods For Production Of Immunoglobulins

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US Patent:
20100239594, Sep 23, 2010
Filed:
Aug 3, 2006
Appl. No.:
11/498522
Inventors:
Vidadi Yusibov - Havertown PA, US
Vadim Mett - Newark DE, US
Anna Hull - West Grove PA, US
International Classification:
A61K 39/40
C12P 21/02
C12P 19/34
C12N 5/10
C12N 15/83
C07K 16/12
C07H 21/04
A61P 31/04
A01H 5/00
A01K 67/00
US Classification:
4241641, 435 696, 435 912, 435419, 4353201, 5303873, 5303895, 536 2353, 536 2433, 800298, 800 13
Abstract:
Provided are oligonucleotides for isolating human antibody cDNAs from cells or cell lines, such as hybridomas. The invention also provides cDNAs that encode at least one provided CDR of a heavy chain or a light chain of a human monoclonal antibody that binds to protective antigen; and cDNAs that encode at least one provided CDR of a heavy chain or a light chain of a human monoclonal antibody that binds to lethal factor. The invention further provides expression vectors that contain one or more cDNAs isolated according to the methods of the invention, host cells expressing one or more inventive cDNAs, and transgenic plants and animals that express one or more inventive cDNAs. In certain embodiments of the invention the expression system is a plant-based expression system. The invention further provides antibody compositions comprising one or more antibodies produced by expressing a cDNA isolated according to the methods of the invention in a suitable expression system. Additionally encompassed in the invention are kits containing one or more of provided compositions, as well as methods of production and use of provided compositions.
Vadim L Mett from Hartford, KY, age ~66 Get Report