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Uma Kuchibhotla

from Indianapolis, IN
Age ~62

Uma Kuchibhotla Phones & Addresses

  • 12604 Bent Oak Ln, Indianapolis, IN 46236 (317) 823-5909
  • 3534 Idlewood Trl, Indianapolis, IN 46214 (317) 297-7646
  • Valley Village, CA
  • Sunderland, MA
  • Dallas, TX

Work

Company: Eli lilly Position: Cso

Education

Degree: Doctorates, Doctor of Philosophy School / High School: Indian Institute of Science (Iisc) 1984 to 1991 Specialities: Philosophy

Industries

Research

Resumes

Resumes

Uma Kuchibhotla Photo 1

Uma Kuchibhotla

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Location:
Indianapolis, IN
Industry:
Research
Work:
Eli Lilly
CSO
Education:
Indian Institute of Science (Iisc) 1984 - 1991
Doctorates, Doctor of Philosophy, Philosophy

Publications

Us Patents

Heterologous G-Csf Fusion Proteins

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US Patent:
20080108560, May 8, 2008
Filed:
Feb 21, 2003
Appl. No.:
10/506455
Inventors:
John Michael Beals - Indianapolis IN, US
Uma Kuchibhotla - Indianapolis IN, US
Assignee:
ELI LILLY AND COMPANY - Indianapolis IN
International Classification:
A61K 38/00
A61P 43/00
C07H 21/04
C07K 16/00
C12N 15/00
C12N 5/04
US Classification:
514 12, 4353201, 435358, 530350, 536 231, 536 234
Abstract:
The present invention encompasses heterologous fusion 5 proteins comprising a hyperglycsoylated G-CSF analog fused to proteins such as albumin and the Fc portion of animmunoglobulin which act to extend the in vivo half-life of the protein compared to native G-CSF. These fusion proteins are particularly suited for the treatment of conditions 10 treatable by stimulation of circulating neutrophils, such as after chemotherapy regimens or in chronic congenital neutropenia.

Pegylated Abeta Fab

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US Patent:
20100015155, Jan 21, 2010
Filed:
Jan 9, 2008
Appl. No.:
12/521309
Inventors:
Kelly Renee Bales - Coatesville IN, US
Thomas Frank Bumol - Indianapolis IN, US
Chi-Kin Chow - Indianapolis IN, US
Ronald Bradley Demattos - Fishers IN, US
Ryan John Hansen - Carmel IN, US
Uma Kuchibhotla - Indianapolis IN, US
Jirong Lu - Carmel IN, US
Peter Colon McDonnell - Indianapolis IN, US
International Classification:
A61K 39/395
C07K 16/00
A61P 25/28
US Classification:
4241391, 5303879
Abstract:
A method to treat conditions associated with Aβ peptide activity both prophylactically and therapeutically is described. The method employs humanized antibody fragments that specifically bind human Aβ peptide between amino acid positions 13-28, wherein the antibody fragments are covalently attached to a polyethylene glycol (PEG) molecule.

Hyperglycosylated Polypeptides

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US Patent:
20040254351, Dec 16, 2004
Filed:
Feb 19, 2003
Appl. No.:
10/362385
Inventors:
John Beals - Indianapolis IN, US
Joe Berry - Greenwood IN, US
Marcia Jones - Franklin IN, US
Uma Kuchibhotla - Indianapolis IN, US
Radhakrishnan Rathnachalam - Carmel IN, US
International Classification:
C07K014/535
US Classification:
530/351000
Abstract:
The present invention addresses the need for better pharmaceutical agents for treating patients that have reduced circulating levels of neutrophilic granulocytes, such as after chemotherpay regimens or in chronic congenital neutropneia by providing novel biological active glycosylated G-CSF analogs.
Uma Kuchibhotla from Indianapolis, IN, age ~62 Get Report